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Author

Christophe Gonçalves

Observed names: C Goncalves, C Goncalvès, Christophe Goncalves, Goncalves, Christophe
Observed institutions: Centre National de la Recherche Scientifique, Institut Pasteur, Jewish General Hospital, Institut National de la Recherche Scientifique, Lady Davis Institute for Medical Research, University of Manitoba, McGill University
ORCID: 0000-0003-2660-1616
Observed ORCID: 0000-0003-2660-1616
OpenAlex ID: A5019238945
Phosphorylation of eIF4E promotes EMT and metastasis via translational control of SNAIL and MMP-3
2014 · N Robichaud, S V del Rincon, et al. · Oncogene · 259
Peroxisomes and cancer: The role of a metabolic specialist in a disease of aberrant metabolism
2018 · Michael S. Dahabieh, Erminia Di Pietro, et al. · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · 96
MNK1/2 inhibition limits oncogenicity and metastasis of KIT-mutant melanoma
2017 · Yao Zhan, Jun Guo, et al. · Journal of Clinical Investigation · 76
Use of allostery to identify inhibitors of calmodulin-induced activation of Bacillus anthracis edema factor
2010 · Elodie Laine, Christophe Goncalves, et al. · Proceedings of the National Academy of Sciences · 75
Inhibiting the MNK1/2-eIF4E axis impairs melanoma phenotype switching and potentiates antitumor immune responses
2021 · Fan Huang, Christophe Gonçalves, et al. · Journal of Clinical Investigation · 63
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Peroxisomes protect lymphoma cells from HDAC inhibitor-mediated apoptosis
2017 · Michael S Dahabieh, ZongYi Ha, et al. · Cell Death and Differentiation · 52
The MNK1/2–eIF4E Axis Supports Immune Suppression and Metastasis in Postpartum Breast Cancer
2021 · Qianyu Guo, Margarita Bartish, et al. · Cancer Research · 47
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Peroxisome disruption alters lipid metabolism and potentiates antitumor response with MAPK-targeted therapy in melanoma
2023 · Fan Huang, Feiyang Cai, et al. · Journal of Clinical Investigation · 46
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The role of eIF4F-driven mRNA translation in regulating the tumour microenvironment
2023 · Margarita Bartish, Madelyn J. Abraham, et al. · Nature reviews. Cancer · 39
Morbillivirus Control of the Interferon Response: Relevance of STAT2 and mda5 but Not STAT1 for Canine Distemper Virus Virulence in Ferrets
2013 · Nicholas Svitek, Ingo Gerhauser, et al. · Journal of Virology · 39
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MNK1/NODAL Signaling Promotes Invasive Progression of Breast Ductal Carcinoma In Situ
2019 · Qianyu Guo, Vivian Z. Li, et al. · Cancer Research · 36
Translation of cancer immunotherapy from the bench to the bedside
2019 · Qianyu Guo, Fan Huang, et al. · Advances in cancer research · 35
MNK2 governs the macrophage antiinflammatory phenotype
2020 · Margarita Bartish, Dongmei Tong, et al. · Proceedings of the National Academy of Sciences · 34
The Role of eIF4E in Response and Acquired Resistance to Vemurafenib in Melanoma
2015 · Yao Zhan, Michael S. Dahabieh, et al. · Journal of Investigative Dermatology · 29
Silencing PEX26 as an unconventional mode to kill drug-resistant cancer cells and forestall drug resistance
2021 · Michael S. Dahabieh, Fan Huang, et al. · Autophagy · 25
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MNK1 signaling induces an ANGPTL4-mediated gene signature to drive melanoma progression
2020 · William Yang, Elie Khoury, et al. · Oncogene · 23
A Non-Hazardous Deparaffinization Protocol Enables Quantitative Proteomics of Core Needle Biopsy-Sized Formalin-Fixed and Paraffin-Embedded (FFPE) Tissue Specimens
2022 · Georgia Mitsa, Qianyu Guo, et al. · International Journal of Molecular Sciences · 16
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Apoptotic Blocks in Primary Non-Hodgkin B Cell Lymphomas Identified by BH3 Profiling
2021 · Ryan N. Rys, Claudia M. Wever, et al. · Cancers · 15
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Phosphorylation of eIF4E in the stroma drives the production and spatial organisation of collagen type I in the mammary gland
2022 · Samuel E.J. Preston, Margarita Bartish, et al. · Matrix Biology · 14
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Tunable PhenoCycler imaging of the murine pre-clinical tumour microenvironments
2024 · Madelyn J. Abraham, Christophe Goncalves, et al. · Cell & Bioscience · 10
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Phase Ib Pharmacodynamic Study of the MNK Inhibitor Tomivosertib (eFT508) Combined With Paclitaxel in Patients With Refractory Metastatic Breast Cancer
2024 · Cristiano Ferrario, John Mackey, et al. · Clinical Cancer Research · 8
Inhibition of the MNK1/2–eIF4E Axis Augments Palbociclib-Mediated Antitumor Activity in Melanoma and Breast Cancer
2022 · Sathyen A. Prabhu, Omar Moussa, et al. · Molecular Cancer Therapeutics · 8
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Inhibiting the MNK1/2-eIF4E axis impairs melanoma phenotype switching and potentiates antitumor immune responses
2024 · Fan Huang, Christophe Gonçalves, et al. · Journal of Clinical Investigation · 6
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Blocking tumor-intrinsic MNK1 kinase restricts metabolic adaptation and diminishes liver metastasis
2024 · Samuel E. J. Preston, Michael S. Dahabieh, et al. · Science Advances · 5
Systematic proximal mapping of the classical RAD51 paralogs unravel functionally and clinically relevant interactors for genome stability
2022 · Estelle Simo Cheyou, Jacopo Boni, et al. · PLoS Genetics · 2
Works count: 109
Citation count: 1,068
H-index: 16
I10-index: 20
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