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Klaus Strebhardt

Observed names: K STREBHARDT, K Strebhardt, K. Strebhardt, Klaus I Strebhardt, Klaus M. Strebhardt, Klaus STREBHARDT, Klaus Strebhardt,, Strebhardt Klaus, Strebhardt, K., Strebhardt, Klaus
Observed institutions: Goethe University Frankfurt, Mount Sinai Hospital, German Cancer Research Center, University of Toronto, Lunenfeld-Tanenbaum Research Institute, Princess Margaret Cancer Centre, University Hospital Frankfurt, Krankenhaus Nordwest, Georg Speyer Haus, Deutsches Konsortium für Translationale Krebsforschung, Nara Institute of Science and Technology
ORCID: 0000-0003-2173-9763
Observed ORCID: 0000-0003-2173-9763
OpenAlex ID: A5019378375
Paul Ehrlich's magic bullet concept: 100 years of progress
2008 · Klaus Strebhardt, Axel Ullrich · Nature reviews. Cancer · 1,457
Targeting polo-like kinase 1 for cancer therapy
2006 · Klaus Strebhardt, Axel Ullrich · Nature reviews. Cancer · 842
Eph Receptors and Ligands Comprise Two Major Specificity Subclasses and Are Reciprocally Compartmentalized during Embryogenesis
1996 · Nicholas W Gale, Sacha J Holland, et al. · Neuron · 839
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Multifaceted polo-like kinases: drug targets and antitargets for cancer therapy
2010 · Klaus Strebhardt · Nature Reviews Drug Discovery · 654
Polo-like kinases and oncogenesis
2005 · Frank Eckerdt, Juping Yuan, et al. · Oncogene · 365
Effect of RNA Silencing of Polo-Like Kinase-1 (PLK1) on Apoptosis and Spindle Formation in Human Cancer Cells
2002 · B. Spankuch-Schmitt, J. Bereiter-Hahn, et al. · JNCI Journal of the National Cancer Institute · 328
Prognostic significance of polo-like kinase (PLK) expression in non-small cell lung cancer
1997 · Georg Wolf, Robert Elez, et al. · Oncogene · 323
Induction and down-regulation of PLK, a humanserine/threonine kinase expressed in proliferating cells andtumors.
1994 · U Holtrich, G Wolf, et al. · Proceedings of the National Academy of Sciences · 275
Caspase-8: The double-edged sword
2020 · Ranadip Mandal, Joan Compte Barrón, et al. · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · 253
Inhibition of Polo-like Kinase 1 by Blocking Polo-Box Domain-Dependent Protein-Protein Interactions
2008 · Wolfgang Reindl, Juping Yuan, et al. · Chemistry & Biology · 232
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Prognostic significance of polo-like kinase (PLK) expression in squamous cell carcinomas of the head and neck.
1999 · R Knecht, R Elez, et al. · PubMed · 231
Trastuzumab-modified nanoparticles: Optimisation of preparation and uptake in cancer cells
2006 · Isabel Steinhauser, Birgit Spänkuch, et al. · Biomaterials · 216
Highly Specific HER2-mediated Cellular Uptake of Antibody-modified Nanoparticles in Tumour Cells
2004 · Heidrun Wartlick, Kerstin Michaelis, et al. · Journal of drug targeting · 211
The polo‐like protein kinases Fnk and Snk associate with a Ca2+‐ and integrin‐binding protein and are regulated dynamically with synaptic plasticity
1999 · Gunther Kauselmann, Markus Weiler, et al. · The EMBO Journal · 204
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Cyclin B1 depletion inhibits proliferation and induces apoptosis in human tumor cells
2004 · Juping Yuan, Ruilan Yan, et al. · Oncogene · 203
PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor
1998 · Björn Hock, Beatrix Böhme, et al. · Proceedings of the National Academy of Sciences · 198
Identification of high risk breast-cancer patients by gene expression profiling
2002 · André Ahr, Thomas Karn, et al. · The Lancet · 187
Expression of polo‐like kinase (PLK1) in thin melanomas: a novel marker of metastatic disease
2002 · Lucas Kneisel, Klaus Strebhardt, et al. · Journal of Cutaneous Pathology · 158
Disseminated tumor cells in the bone marrow of patients with ductal carcinoma in situ
2011 · Nicole Sänger, Katharina E. Effenberger, et al. · International Journal of Cancer · 153
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Downregulation of human polo-like kinase activity by antisense oligonucleotides induces growth inhibition in cancer cells
2002 · Birgit Spänkuch-Schmitt, Georg Wolf, et al. · Oncogene · 147
Silencing of the HER2/neu Gene by siRNA Inhibits Proliferation and Induces Apoptosis in HER2/neu-Overexpressing Breast Cancer Cells
2004 · Timo Faltus, Juping Yuan, et al. · Neoplasia · 139
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Targeting CDK1 and MEK/ERK Overcomes Apoptotic Resistance in BRAF-Mutant Human Colorectal Cancer
2017 · Peng Zhang, Hisato Kawakami, et al. · Molecular Cancer Research · 134
Stable gene silencing of cyclin B1 in tumor cells increases susceptibility to taxol and leads to growth arrest in vivo
2005 · J Yuan, A Krämer, et al. · Oncogene · 128
Targeting CDK9 for Anti-Cancer Therapeutics
2021 · Ranadip Mandal, Sven Becker, et al. · Cancers · 127
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Tumour cell delivery of antisense oligonuclceotides by human serum albumin nanoparticles
2004 · Heidrun Wartlick, Birgit Spänkuch-Schmitt, et al. · Journal of Controlled Release · 123
Works count: 202
Citation count: 13,430
H-index: 61
I10-index: 130
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