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Eric T. Williams
Observed name:
Eric T Williams
Observed institutions:
Eli Lilly (United States),
Molecular Templates (United States),
Eisai (United Kingdom),
Eisai (United States),
The University of Texas Health Science Center at Houston
ORCID:
0000-0001-9803-4230
Observed ORCID:
0000-0001-9803-4230
OpenAlex ID:
A5019520358
Characterization of Recombinant Human Carboxylesterases: Fluorescein Diacetate as a Probe Substrate for Human Carboxylesterase 2
2011
·
Jie Wang
, Eric T. Williams
, et al.
·
Drug Metabolism and Disposition
·
130
The Biotransformation of Prasugrel, a New Thienopyridine Prodrug, by the Human Carboxylesterases 1 and 2
2008
·
Eric T. Williams
, Karen O. Jones
, et al.
·
Drug Metabolism and Disposition
·
128
CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing’s sarcoma
2019
·
Nathan T. Ross
, Felix Lohmann
, et al.
·
Nature Chemical Biology
·
93
Characterization of the Expression and Activity of Carboxylesterases 1 and 2 from the Beagle Dog, Cynomolgus Monkey, and Human
2011
·
Eric T. Williams
, James A. Bacon
, et al.
·
Drug Metabolism and Disposition
·
72
A Phase I Dose-Escalation Study to Evaluate the Safety and Tolerability of Evofosfamide in Combination with Ipilimumab in Advanced Solid Malignancies
2021
·
Aparna Hegde
, Priyamvada Jayaprakash
, et al.
·
Clinical Cancer Research
·
63
Estrogen Regulation of the Cytochrome P450 3A Subfamily in Humans
2004
·
Eric T. Williams
, Malgorzata Leyk
, et al.
·
Journal of Pharmacology and Experimental Therapeutics
·
51
Genomic analysis of the carboxylesterases: Identification and classification of novel forms
2010
·
Eric T. Williams
, He Wang
, et al.
·
Molecular Phylogenetics and Evolution
·
35
Phenotypic screen identifies calcineurin-sparing FK506 analogs as BMP potentiators for treatment of acute kidney injury
2021
·
Marie-Hélène Larraufie
, Xiaolin Gao
, et al.
·
Cell chemical biology
·
27
Investigation of the Metabolism of Rufinamide and Its Interaction with Valproate
2011
·
Eric T. Williams
, J. Eric Carlson
, et al.
·
Drug Metabolism Letters
·
24
Effect of buffer components and carrier solvents on in vitro activity of recombinant human carboxylesterases
2007
·
Eric T. Williams
, Mariam E. Ehsani
, et al.
·
Journal of Pharmacological and Toxicological Methods
·
23
Defining relationships between the known members of the cytochrome P450 3A subfamily, including five putative chimpanzee members
2004
·
Eric T. Williams
, Andrei S. Rodin
, et al.
·
Molecular Phylogenetics and Evolution
·
17
Safety and Efficacy of Engineered Toxin Body MT-3724 in Relapsed or Refractory B-cell Non-Hodgkin's Lymphomas and Diffuse Large B-cell Lymphoma
2022
·
Paul A. Hamlin
, Vasile Musteata
, et al.
·
Cancer Research Communications
·
12
MT-5111: A novel HER2 targeting engineered toxin body in clinical development.
2020
·
Roger J. Waltzman
, Asis Sarkar
, et al.
·
Journal of Clinical Oncology
·
10
Reversible Inhibition of Human Carboxylesterases by Acyl Glucuronides
2013
·
Natalie R. Inoue
, Adrian Hall
, et al.
·
Drug Metabolism and Disposition
·
9
Discovery of a brain-sparing GIRK1/4 inhibitor for pharmacological cardioversion of atrial fibrillation
2023
·
Stefan Peukert
, Hatice Belgin Gulgeze Efthymiou
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
7
The chimpanzee cytochrome P450 3A subfamily: Is our closest related species really that similar?
2007
·
Eric T. Williams
, Katherine R. Schouest
, et al.
·
Comparative Biochemistry and Physiology Part D Genomics and Proteomics
·
5
Abstract P1-18-35: MT-5111, a novel HER2 targeting engineered toxin body, under clinical development to overcome mechanisms of resistance to existing HER2 targeted therapies
2020
·
Jack P Higgins
, Asis Sarkar
, et al.
·
Cancer Research
·
4
Monotherapy Activity with the First CD20-Targeted Immunotoxin, MT-3724, in Subjects with Relapsed/Refractory (R/R) Diffuse Large B-Cell Lymphoma (DLBCL)
2019
·
Paul A. Hamlin
, Vasile Musteata
, et al.
·
Blood
·
4
Abstract CT130: Phase 1 study of the novel immunotoxin MT-5111 in patients with HER-2+tumors
2021
·
Zev A. Wainberg
, Monica M. Mita
, et al.
·
Cancer Research
·
3
Author Correction: CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing’s sarcoma
2020
·
Nathan T. Ross
, Felix Lohmann
, et al.
·
Nature Chemical Biology
·
1
PDF
Chimpanzee: A predictive model for the human cytochrome P450 3A subfamily
2006
·
Eric T. Williams
·
Digital Commons-TMC (Texas Medical Center)
·
1
4.50eP Pharmacokinetic and pharmacodynamic translation of ENTR-601-44, an investigational therapy for patients with exon 44 skip-amenable DMD
2026
·
Ridhi Parasrampuria
, Eric T. Williams
, et al.
·
Neuromuscular Disorders
Data from Safety and Efficacy of Engineered Toxin Body MT-3724 in Relapsed or Refractory B-cell Non-Hodgkin's Lymphomas and Diffuse Large B-cell Lymphoma
2023
·
Paul A. Hamlin
, Vasile Musteata
, et al.
Supplementary Tables 1-7, Figures 1-3 from Safety and Efficacy of Engineered Toxin Body MT-3724 in Relapsed or Refractory B-cell Non-Hodgkin's Lymphomas and Diffuse Large B-cell Lymphoma
2023
·
Paul A. Hamlin
, Vasile Musteata
, et al.
Data from Safety and Efficacy of Engineered Toxin Body MT-3724 in Relapsed or Refractory B-cell Non-Hodgkin's Lymphomas and Diffuse Large B-cell Lymphoma
2023
·
Paul A. Hamlin
, Vasile Musteata
, et al.
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Works count:
32
Citation count:
719
H-index:
12
I10-index:
13
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