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Nirvana A. Gohar

Observed name: Gohar, Nirvana A.
ORCID: 0000-0002-6442-7762
Observed ORCID: 0000-0002-6442-7762
OpenAlex ID: A5019584271
Development of new spiro[1,3]dithiine-4,11′-indeno[1,2-b]quinoxaline derivatives as S. aureus Sortase A inhibitors and radiosterilization with molecular modeling simulation
2022 · Ahmed Ragab, Moustafa S. Abusaif, et al. · Bioorganic Chemistry · 63
In vitro cytotoxic activity of thiazole-indenoquinoxaline hybrids as apoptotic agents, design, synthesis, physicochemical and pharmacokinetic studies
2020 · Eman A. Fayed, Yousry A. Ammar, et al. · Bioorganic Chemistry · 59
Fluorinated indeno-quinoxaline bearing thiazole moieties as hypoglycaemic agents targeting α -amylase, and α -glucosidase: synthesis, molecular docking, and ADMET studies
2024 · Nirvana A. Gohar, Eman A. Fayed, et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 48
Design, synthesis, cytotoxicity and molecular modeling studies of some novel fluorinated pyrazole-based heterocycles as anticancer and apoptosis-inducing agents
2018 · Eman A. Fayed, Sally I. Eissa, et al. · Molecular Diversity · 48
Design, synthesis, and antitumor evaluation of new pyridazinone scaffolds as dual EGFR/VEGFR-2 kinase inhibitors and apoptotic cells inducers
2025 · Sara Y. Ewieda, Eman M. Ahmed, et al. · Bioorganic Chemistry · 35
Upregulation of BAX and caspase‐3, as well as downregulation of Bcl‐2 during treatment with indeno[1,2‐b]quinoxalin derivatives, mediated apoptosis in human cancer cells
2022 · Eman A. Fayed, Nirvana A. Gohar, et al. · Archiv der Pharmazie · 35
Exploring a novel thiazole derivatives hybrid with fluorinated-indenoquinoxaline as dual inhibitors targeting VEGFR2/AKT and apoptosis inducers against hepatocellular carcinoma with docking simulation
2024 · Moustafa S. Abusaif, Ahmed Ragab, et al. · Bioorganic Chemistry · 33
Novel fluorinated pyrazole-based heterocycles scaffold: cytotoxicity, in silico studies and molecular modelling targeting double mutant EGFR L858R/T790M as antiproliferative and apoptotic agents
2023 · Eman A. Fayed, Nirvana A. Gohar, et al. · Medicinal Chemistry Research · 32
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Discovery and optimization of 2-pyridones as dual h-DHFR/EGFRTK inhibitors with immunomodulatory potential; design, synthesis, anti-proliferative activity, and apoptosis inducer
2025 · Ahmed Ragab, Reham R. Raslan, et al. · European Journal of Medicinal Chemistry · 19
Novel 3‐Substituted‐2H‐Chromene Scaffold Based Fluorinated Hydrophobic Fragment as In‐Vitro Antiproliferative Agents and Apoptosis Inducers Targeting Both VEGFR‐2/BRAFV600E and h‐DHFR With Molecular Docking Simulation
2025 · Mohamed A. Salem, Moustafa S. Abusaif, et al. · Drug Development Research · 12
Novel Pyrrolidine-bearing quinoxaline inhibitors of DNA Gyrase, RNA polymerase and spike glycoprotein
2025 · Maha A. Ebrahim, Triveena M. Ramsis, et al. · Bioorganic Chemistry · 9
Unlocking Therapeutic Potential of Novel Thieno-Oxazepine Hybrids as Multi-Target Inhibitors of AChE/BChE and Evaluation Against Alzheimer’s Disease: In Vivo, In Vitro, Histopathological, and Docking Studies
2025 · Khulood H. Oudah, Mazin A. A. Najm, et al. · Pharmaceuticals · 7
Pyridazine and Pyridazinone in Medicinal Chemistry: Synthesis and Antiinflammatory Pathways Targeting TxA 2 , TNF-α, and IL-6
2025 · Soha H. Emam, Eman M. Ahmed, et al. · Mini-Reviews in Medicinal Chemistry · 5
From bench to brain: novel thieno-oxazine hybrids as potent pleiotropic anti-Alzheimer’s agents with in vivo / in vitro validation and in silico insights
2026 · Eman A. Fayed, Mazin A. A. Najm, et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 3
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Newly synthesized ethenyl pyridazines and ethenyl pyridazinones as anti-inflammatory agents with COVID-19 suppressing potential
2025 · Eman M. Ahmed, Nadia A. Khalil, et al. · Bioorganic Chemistry · 2
Insights into novel benzo[h]quinoline-based 2-thioxothiazolidin-4-one and thiazol-4-one hybrids as potential antimicrobial, and antibiofilm candidates: Design, synthesis, molecular modeling, and in-silico ADME studies
2026 · Reham R. Raslan, Sally I. Eissa, et al. · Bioorganic Chemistry · 1
A structural blueprint for antibacterial discovery: microwave- and ultrasound-assisted synthesis of pyrrolidine-fused quinoxalines as novel inhibitors of DNA gyrase and biofilm
2026 · Eman A. Fayed, Mazin A. A. Najm, et al. · RSC Advances · 1
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Cyanopyridine-based derivatives as potent anticancer agents: Integrating in silico analysis and in vitro biological targeting of the EGFR/AKT/MAPK Signaling Cascade
2026 · Shimaa M. Alhamaky, Marwa S.A. Hassan, et al. · Bioorganic Chemistry
Discovery of New Pyrazole‐Linked Pyridine Derivatives as Multi‐Target Anti‐Inflammatory Agents With Immunomodulatory Potential
2026 · Mohamed A. Salem, Reham R. Raslan, et al. · Drug Development Research
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Author response for "A Structural Blueprint for Antibacterial Discovery: Microwave- and Ultrasound-Assisted Synthesis of Pyrrolidine-Fused Quinoxalines as Novel Inhibitors of DNA Gyrase and Biofilm"
2026 · Eman A. Fayed, Mazin A. A. Najm, et al. · Publons reviews and discussion
From bench to brain: novel thieno-oxazine hybrids as potent pleiotropic anti-Alzheimer’s agents with in vivo/in vitro validation and in silico insights
2026 · Fayed, Eman A., Najm, Mazin A. A., et al. · Figshare
Schiffê¼s Base-indenoquinoxaline Hybrids as Apoptotic Inducing Agents, Design, Synthesis, in Vitro Cytotoxicity, Physicochemical and Pharmacokinetic Studies
2020 · Eman A. Fayed, Nirvana A. Gohar, et al. · Journal of Applied Pharmacy
Works count: 23
Citation count: 412
H-index: 10
I10-index: 10
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