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Hitesh J. Sanganee

Observed names: H J Sanganee, H Sanganee, H. J. SANGANEE, H. Sanganee, HITESH SANGANEE, Hitesh J Sanganee, Hitesh Sanganee, Sanganee, H.J., Sanganee, Hitesh J.
Observed institutions: Florida State University, AstraZeneca (United Kingdom), University of Michigan, Melbourn Science Park, University of Oxford, Alexion Pharmaceuticals (United States), Tianjin Medical University
OpenAlex ID: A5020130403
Screening of a library of phage-displayed peptides identifies human Bcl-2 as a taxol-binding protein 1 1Edited by I. A. Wilson
1999 · Diane J Rodi, Robert W Janes, et al. · Journal of Molecular Biology · 224
Rare variant associations with plasma protein levels in the UK Biobank
2023 · Ryan S. Dhindsa, Oliver S. Burren, et al. · Nature · 189
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An Integrated Approach to Fragment-Based Lead Generation:Philosophy, Strategy and Case Studies from AstraZenecas Drug Discovery Programmes
2007 · Jeffrey Albert, Niklas Blomberg, et al. · Current Topics in Medicinal Chemistry · 126
4-Substituted-5,5-dimethyl oxazolidin-2-ones as effective chiral auxiliaries for enolate alkylations and Michael additions
1995 · Stephen G. Davies, Hitesh J. Sanganee · Tetrahedron Asymmetry · 102
Asymmetric alkylations using SuperQuat auxiliaries—an investigation into the synthesis and stability of enolates derived from 5,5-disubstituted oxazolidin-2-ones
1999 · Steven D. Bull, Stephen G. Davies, et al. · Journal of the Chemical Society Perkin Transactions 1 · 87
One-Pot Catalytic Enantioselective Synthesis of Tetrahydropyridines via a Nitro-Mannich/Hydroamination Cascade
2012 · David M. Barber, Hitesh J. Sanganee, et al. · Organic Letters · 73
The ?SuperQuat? (R)-4-phenyl-5,5-dimethyl oxazolidin-2-one as an effective chiral auxiliary for conjugate additions: Asymmetric synthesis of (?)-Aplysillamide B
1999 · Stephen G. Davies, Hitesh J. Sanganee, et al. · Tetrahedron · 71
A Practical Procedure for the Multigram Synthesis of the SuperQuat Chiral Auxiliaries
1998 · Steven D. Bull, Stephen G. Davies, et al. · Synlett · 69
One-pot nitro-Mannich/hydroamination cascades for the direct synthesis of 2,5-disubstituted pyrroles using base and gold catalysis
2011 · David M. Barber, Hitesh Sanganee, et al. · Chemical Communications · 61
Genetic architecture of telomere length in 462,666 UK Biobank whole-genome sequences
2024 · Oliver S. Burren, Ryan S. Dhindsa, et al. · Nature Genetics · 58
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Pioneering government-sponsored drug repositioning collaborations: progress and learning
2015 · Donald E. Frail, Madeleine Brady, et al. · Nature Reviews Drug Discovery · 57
One-Pot Asymmetric Nitro-Mannich/Hydroamination Cascades for the Synthesis of Pyrrolidine Derivatives: Combining Organocatalysis and Gold Catalysis
2014 · David M. Barber, Andrej Ďuriš, et al. · ACS Catalysis · 55
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Cathepsin C Inhibitors: Property Optimization and Identification of a Clinical Candidate
2014 · Mark Furber, Anna-Karin Tiden, et al. · Journal of Medicinal Chemistry · 54
SuperQuat N-acyl-5,5-dimethyloxazolidin-2-ones for the asymmetric synthesis of α-alkyl and β-alkyl aldehydes
2003 · Steven D. Bull, Stephen G. Davies, et al. · Organic & Biomolecular Chemistry · 54
Discovery of potent CRTh2 (DP2) receptor antagonists
2006 · Timothy N. Birkinshaw, Simon J. Teague, et al. · Bioorganic & Medicinal Chemistry Letters · 42
SuperQuat, (S)-4-benzyl-5,5-dimethyl-oxazolidin-2-one for the asymmetric synthesis of α-substituted-aldehydes
2000 · Steven D Bull, Stephen G Davies, et al. · Tetrahedron Asymmetry · 42
Potent Dual Inhibitors of TORC1 and TORC2 Complexes (KU-0063794 and KU-0068650) Demonstrate In Vitro and Ex Vivo Anti-Keloid Scar Activity
2013 · Farhatullah Syed, Hitesh J. Sanganee, et al. · Journal of Investigative Dermatology · 38
Substituted indole-1-acetic acids as potent and selective CRTh2 antagonists—discovery of AZD1981
2011 · Tim Luker, Roger Bonnert, et al. · Bioorganic & Medicinal Chemistry Letters · 38
Synthesis and utility of the 3,3-dimethyl-5-substituted-2-pyrrolidinone ‘Quat’ chiral auxiliary
2002 · Stephen G. Davies, Darren J. Dixon, et al. · Tetrahedron Asymmetry · 37
Asymmetric aldol and alkylation reactions mediated by the “quat” chiral auxiliary (R)-(−)-5-methyl-3,3-dimethyl-2-pyrrolidinone
1994 · Stephen G. Davies, Gilles J.-M. Doisneau, et al. · Tetrahedron Letters · 37
Synthesis of 5-substituted-3,3-dimethyl-2-pyrrolidinones: “quat” chiral auxiliaries
1994 · Stephen G. Davies, Gilles J.-M. Doisneau, et al. · Tetrahedron Letters · 35
Activation of the Wnt Pathway through AR79, a GSK3β Inhibitor, Promotes Prostate Cancer Growth in Soft Tissue and Bone
2013 · Yuan Jiang, Jinlu Dai, et al. · Molecular Cancer Research · 32
Stereoselective functionalisation of SuperQuat enamides: asymmetric synthesis of homochiral 1,2-diols and α-benzyloxy carbonyl compounds
2008 · Caroline Aciro, Stephen G. Davies, et al. · Tetrahedron · 31
Discovery of small molecule human C5a receptor antagonists
2009 · Hitesh J. Sanganee, Andrew Baxter, et al. · Bioorganic & Medicinal Chemistry Letters · 27
Oxidative Functionalisation of SuperQuat Enamides: Asymmetric Synthesis of Homochiral 1,2 Diols
2003 · Stephen G. Davies, Min-Suk Key, et al. · Synlett · 27
Works count: 95
Citation count: 1,877
H-index: 26
I10-index: 35
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