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Sofia Francia

Site-specific DICER and DROSHA RNA products control the DNA-damage response
2012 · Sofia Francia, Flavia Michelini, et al. · Nature · 553
Damage-induced lncRNAs control the DNA damage response through interaction with DDRNAs at individual double-strand breaks
2017 · Flavia Michelini, Sethuramasundaram Pitchiaya, et al. · Nature Cell Biology · 400
DICER, DROSHA and DNA damage response RNAs are necessary for the secondary recruitment of DNA damage response factors
2016 · Sofia Francia, Matteo Cabrini, et al. · Journal of Cell Science · 145
A damaged genome’s transcriptional landscape through multilayered expression profiling around in situ-mapped DNA double-strand breaks
2017 · Fabio Iannelli, Alessandro Galbiati, et al. · Nature Communications · 133
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From “Cellular” RNA to “Smart” RNA: Multiple Roles of RNA in Genome Stability and Beyond
2018 · Flavia Michelini, Ameya P. Jalihal, et al. · Chemical Reviews · 89
MRE11-RAD50-NBS1 Complex Is Sufficient to Promote Transcription by RNA Polymerase II at Double-Strand Breaks by Melting DNA Ends
2021 · Sheetal Sharma, Roopesh Anand, et al. · Cell Reports · 74
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Pharmacological boost of DNA damage response and repair by enhanced biogenesis of DNA damage response RNAs
2019 · Ubaldo Gioia, Sofia Francia, et al. · Scientific Reports · 71
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DNA Damage Triggers a New Phase in Neurodegeneration
2020 · Fabio Pessina, Ubaldo Gioia, et al. · Trends in Genetics · 62
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Telomere and Telomerase Modulation by the Mammalian Rad9/Rad1/Hus1 DNA-Damage-Checkpoint Complex
2006 · Sofia Francia, Robert S. Weiss, et al. · Current Biology · 53
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Transcriptional and post-transcriptional regulation of the ionizing radiation response by ATM and p53
2017 · Ishwarya Venkata Narayanan, Michelle T. Paulsen, et al. · Scientific Reports · 50
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Post-Translational Modifications Modulate Proteinopathies of TDP-43, FUS and hnRNP-A/B in Amyotrophic Lateral Sclerosis
2021 · Stefania Farina, Francesca Esposito, et al. · Frontiers in Molecular Biosciences · 45
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Express or repress? The transcriptional dilemma of damaged chromatin
2017 · Ilaria Capozzo, Fabio Iannelli, et al. · FEBS Journal · 36
A missense MT-ND5 mutation in differentiated Parkinson Disease cytoplasmic hybrid induces ROS-dependent DNA Damage Response amplified by DROSHA
2017 · Daniela Pignataro, Sofia Francia, et al. · Scientific Reports · 27
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Non-Coding RNA: Sequence-Specific Guide for Chromatin Modification and DNA Damage Signaling
2015 · Sofia Francia · Frontiers in Genetics · 26
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DROSHA is recruited to DNA damage sites by the MRN complex to promote non-homologous end joining
2021 · Matteo Cabrini, Marco Roncador, et al. · Journal of Cell Science · 23
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DNA damage response defects induced by the formation of TDP-43 and mutant FUS cytoplasmic inclusions and their pharmacological rescue
2025 · Stefania Modafferi, Stefania Farina, et al. · Cell Death and Differentiation · 16
RNase A treatment and reconstitution with DNA damage response RNA in living cells as a tool to study the role of non-coding RNA in the formation of DNA damage response foci
2019 · Flavia Michelini, Francesca Rossiello, et al. · Nature Protocols · 16
Need telomere maintenance? Call 911
2007 · Sofia Francia, Robert S Weiss, et al. · Cell Division · 14
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TGS1 impacts snRNA 3′-end processing, ameliorates survival motor neuron-dependent neurological phenotypes in vivo and prevents neurodegeneration
2022 · Lu Chen, Caitlin M Roake, et al. · Nucleic Acids Research · 12
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DROSHA, DICER, and damage-induced long ncRNA control BMI1-dependent transcriptional repression at DNA double-strand break
2025 · Francesca Esposito, Ilaria Capozzo, et al. · Cell Reports · 8
Traffic light at DSB –transit regulation between gene transcription and DNA repair
2024 · Stefania Modafferi, Francesca Esposito, et al. · FEBS Letters · 5
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A Role for Human DNA Polymerase λ in Alternative Lengthening of Telomeres
2021 · Elisa Mentegari, Federica Bertoletti, et al. · International Journal of Molecular Sciences · 4
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DNA double-strand break response at a glance
2026 · Francesca Esposito, Sofia Francia · Journal of Cell Science · 3
DROSHA and DICER RNA products control BMI1-dependent transcriptional repression at DNA damage sites
2022 · Sofia Francia, Ilaria Capozzo, et al. · Research Square · 1
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Proteasomal-dependent CHK1 degradation leads to DNA damage accumulation in ALS cellular model systems
2026 · Stefania Modafferi, Valentina Silenzi, et al. · Cell Death and Disease
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Works count: 28
Citation count: 1,866
H-index: 16
I10-index: 19
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