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Sachiko Okamoto

Complete sequencing and characterization of 21,243 full-length human cDNAs
2003 · Toshio Ota, Yutaka Suzuki, et al. · Nature Genetics · 937
P-TEFb-Mediated Phosphorylation of hSpt5 C-Terminal Repeats Is Critical for Processive Transcription Elongation
2006 · Tomoko Yamada, Yuki Yamaguchi, et al. · Molecular Cell · 434
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Improved Expression and Reactivity of Transduced Tumor-Specific TCRs in Human Lymphocytes by Specific Silencing of Endogenous TCR
2009 · Sachiko Okamoto, Junichi Mineno, et al. · Cancer Research · 188
Safety and persistence of WT1-specific T-cell receptor gene−transduced lymphocytes in patients with AML and MDS
2017 · Isao Tawara, Shinichi Kageyama, et al. · Blood · 179
Highly efficient genome editing for single-base substitutions using optimized ssODNs with Cas9-RNPs
2019 · Sachiko Okamoto, Yasunori Amaishi, et al. · Scientific Reports · 135
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Novel adoptive T-cell immunotherapy using a WT1-specific TCR vector encoding silencers for endogenous TCRs shows marked antileukemia reactivity and safety
2011 · Toshiki Ochi, Hiroshi Fujiwara, et al. · Blood · 124
Antitumor activity of CAR-T cells targeting the intracellular oncoprotein WT1 can be enhanced by vaccination
2018 · Yasushi Akahori, Linan Wang, et al. · Blood · 110
Direct tumor recognition by a human CD4+ T-cell subset potently mediates tumor growth inhibition and orchestrates anti-tumor immune responses
2015 · Junko Matsuzaki, Takemasa Tsuji, et al. · Scientific Reports · 84
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NY-ESO-1-specific redirected T cells with endogenous TCR knockdown mediate tumor response and cytokine release syndrome
2022 · Mikiya Ishihara, Shigehisa Kitano, et al. · Journal for ImmunoTherapy of Cancer · 74
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Hepatitis delta antigen binds to the clamp of RNA polymerase II and affects transcriptional fidelity
2007 · Yuki Yamaguchi, Takashi Mura, et al. · Genes to Cells · 59
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Efficient tumor regression by adoptively transferred CEA-specific CAR-T cells associated with symptoms of mild cytokine release syndrome
2016 · Linan Wang, Ning Ma, et al. · OncoImmunology · 51
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Rapid αβ TCR-mediated responses in γδ T cells transduced with cancer-specific TCR genes
2009 · A Hiasa, H Nishikawa, et al. · Gene Therapy · 49
Gene-Modified Human α/β-T Cells Expressing a Chimeric CD16-CD3ζ Receptor as Adoptively Transferable Effector Cells for Anticancer Monoclonal Antibody Therapy
2014 · Fumihiro Ochi, Hiroshi Fujiwara, et al. · Cancer Immunology Research · 47
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Co-Introduced Functional CCR2 Potentiates In Vivo Anti-Lung Cancer Functionality Mediated by T Cells Double Gene-Modified to Express WT1-Specific T-Cell Receptor
2013 · Hiroaki Asai, Hiroshi Fujiwara, et al. · PLoS ONE · 47
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Development of a novel redirected T-cell–based adoptive immunotherapy targeting human telomerase reverse transcriptase for adult T-cell leukemia
2013 · Yukihiro Miyazaki, Hiroshi Fujiwara, et al. · Blood · 42
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A Promising Vector for TCR Gene Therapy: Differential Effect of siRNA, 2A Peptide, and Disulfide Bond on the Introduced TCR Expression
2012 · Sachiko Okamoto, Yasunori Amaishi, et al. · Molecular Therapy — Nucleic Acids · 37
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Development of a chimeric cytokine receptor that captures IL-6 and enhances the antitumor response of CAR-T cells
2024 · Toshiaki Yoshikawa, Yusuke Ito, et al. · Cell Reports Medicine · 27
Preclinical study of a DNA vaccine targeting SARS-CoV-2
2022 · Hiroki Hayashi, Jiao Sun, et al. · Current Research in Translational Medicine · 26
CAR-Modified Vγ9Vδ2 T Cells Propagated Using a Novel Bisphosphonate Prodrug for Allogeneic Adoptive Immunotherapy
2023 · Yizheng Wang, Linan Wang, et al. · International Journal of Molecular Sciences · 25
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Development of Engineered T Cells Expressing a Chimeric CD16-CD3ζ Receptor to Improve the Clinical Efficacy of Mogamulizumab Therapy Against Adult T-Cell Leukemia
2016 · Hiroki Tanaka, Hiroshi Fujiwara, et al. · Clinical Cancer Research · 25
Development of a Unique T Cell Receptor Gene-Transferred Tax-Redirected T Cell Immunotherapy for Adult T Cell Leukemia
2020 · Koji Kawamura, Yukie Tanaka, et al. · Transplantation and Cellular Therapy · 19
Tumor Growth Suppression of Pancreatic Cancer Orthotopic Xenograft Model by CEA-Targeting CAR-T Cells
2023 · Osamu Sato, Takahiro Tsuchikawa, et al. · Cancers · 17
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Adoptive transfer of genetically modified Wilms' tumor 1–specific T cells in a novel malignant skull base meningioma model
2013 · Kenichiro Iwami, Atsushi Natsume, et al. · Neuro-Oncology · 15
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Antileukemia multifunctionality of CD4+ T cells genetically engineered by HLA class I-restricted and WT1-specific T-cell receptor gene transfer
2015 · H Fujiwara, T Ochi, et al. · Leukemia · 14
Stimulation Side-Dependent Asymmetrical Secretion of Poly I:Poly C-Induced Interferon-β from Polarized Epithelial Cell Lines
1999 · Sachiko Okamoto, Kiyo Nakanishi, et al. · Biochemical and Biophysical Research Communications · 13
Works count: 80
Citation count: 2,854
H-index: 20
I10-index: 26
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