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Yin Gu

CpG-induced tyrosine phosphorylation occurs via a TLR9-independent mechanism and is required for cytokine secretion
2006 · Miguel A. Sanjuan, Navin Rao, et al. · The Journal of Cell Biology · 135
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Targeting the CXCR4 pathway using a novel anti-CXCR4 IgG1 antibody (PF-06747143) in chronic lymphocytic leukemia
2017 · Manoj K. Kashyap, Carlos I. Amaya-Chanaga, et al. · Journal of Hematology & Oncology · 67
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A novel CXCR4 antagonist IgG1 antibody (PF-06747143) for the treatment of hematologic malignancies
2017 · Shu-Hui Liu, Yin Gu, et al. · Blood Advances · 56
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Identification of a Potent and Selective Noncovalent Cathepsin S Inhibitor
2004 · Robin L. Thurmond, Siquan Sun, et al. · Journal of Pharmacology and Experimental Therapeutics · 54
Survival Benefit of Traditional Chinese Herbal Medicine (a Herbal Formula for Invigorating Spleen) for Patients With Advanced Gastric Cancer
2012 · Yan Xu, Ai Guang Zhao, et al. · Integrative Cancer Therapies · 47
Antitumor Efficacy of the Dual PI3K/mTOR Inhibitor PF-04691502 in a Human Xenograft Tumor Model Derived from Colorectal Cancer Stem Cells Harboring a PIK3CA Mutation
2013 · Douglas D. Fang, Cathy C. Zhang, et al. · PLoS ONE · 44
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Anti-Inflammatory Activity in Vitro and in Vivo of the Protein Farnesyltransferase Inhibitor Tipifarnib
2006 · Xiaohua Xue, Kuei-Tai A. Lai, et al. · Journal of Pharmacology and Experimental Therapeutics · 39
Discovery and SAR studies of a novel series of noncovalent cathepsin S inhibitors
2005 · Darin J. Gustin, Clark A. Sehon, et al. · Bioorganic & Medicinal Chemistry Letters · 38
Targeting primary acute myeloid leukemia with a new CXCR4 antagonist IgG1 antibody (PF-06747143)
2017 · Yanyan Zhang, Erika Saavedra, et al. · Scientific Reports · 37
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How aging of the global population is changing oncology
2021 · Yin Fei Gu, Frank P Lin, et al. · ecancermedicalscience · 33
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Pyrazole-based cathepsin S inhibitors with improved cellular potency
2007 · Jianmei Wei, Barbara A. Pio, et al. · Bioorganic & Medicinal Chemistry Letters · 24
Combined gemcitabine and CHK1 inhibitor treatment induces apoptosis resistance in cancer stem cell-like cells enriched with tumor spheroids from a non-small cell lung cancer cell line
2013 · Douglas D. Fang, Joan Cao, et al. · Frontiers of Medicine · 22
Pyrazole-based cathepsin S inhibitors with arylalkynes as P1 binding elements
2009 · Michael K. Ameriks, Frank U. Axe, et al. · Bioorganic & Medicinal Chemistry Letters · 22
Diazinones as P2 replacements for pyrazole-based cathepsin S inhibitors
2010 · Michael K. Ameriks, Scott D. Bembenek, et al. · Bioorganic & Medicinal Chemistry Letters · 20
Pyrazole-based arylalkyne cathepsin S inhibitors. Part II: Optimization of cellular potency
2009 · Michael K. Ameriks, Hui Cai, et al. · Bioorganic & Medicinal Chemistry Letters · 14
Needle‐Plug/Piston‐Based Modular Mesoscopic Design Paradigm Coupled With Microfluidic Device for Point‐of‐Care Pooled Testing
2024 · Baobao Lin, Bao Li, et al. · Advanced Science · 12
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The SAR of 4-substituted (6,6-bicyclic) piperidine cathepsin S inhibitors
2006 · Cheryl A. Grice, Kevin Tays, et al. · Bioorganic & Medicinal Chemistry Letters · 12
TRIM52 positively mediates NF-κB to promote the growth of human benign prostatic hyperplasia cells through affecting TRAF2 ubiquitination
2020 · Jianming Sun, Peng Liu, et al. · Life Sciences · 11
A Novel CXCR4 Antagonist IgG1 Antibody (PF-06747143) for the Treatment of Hematological Malignancies
2014 · Flavia Pernasetti, Shu-Hui Liu, et al. · Blood · 9
A fully integrated microfluidic cartridge for rapid and ultrasensitive nucleic acid detection from oropharyngeal swabs
2025 · Bao Li, Baobao Lin, et al. · Lab on a Chip · 7
In Situ Colorimetric LAMP Based on One-Step Modified Filter Paper to Screen Human Papillomavirus (HPV)16/18 from Clinical Samples
2024 · Tingting Jiao, Peng Sun, et al. · Langmuir · 5
CpG-induced tyrosine phosphorylation occurs via a TLR9-independent mechanism and is required for cytokine secretion
2006 · Miguel A. Sanjuan, Navin Rao, et al. · The Journal of Experimental Medicine · 5
Comparative assessment of the transduction efficiency and safety associated with the delivery of AAV9-GFP vector via lumbar puncture to cynomolgus macaques with and without anti-AAV9 pre-existing antibodies
2024 · Ghiabe H. Guibinga, Janet Do, et al. · Molecular Therapy — Methods & Clinical Development · 3
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Abstract 4483: Establishing patient-derived colorectal cancer stem cell models with a PIK3CA mutation for the development of inhibitory drugs as targeted therapies
2010 · Douglas D. Fang, Yin Gu, et al. · Cancer Research · 1
Roles of Phosphorylated p210bcr/abl and Hsp90 Protein in Apoptosis Induced by Berbamine in K562 Cells.
2006 · Xiaohong Zhang, Jianrong Sun, et al. · Blood · 1
Works count: 43
Citation count: 718
H-index: 14
I10-index: 18
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