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Julie Lotharius

Pathogenesis of parkinson's disease: dopamine, vesicles and α-synuclein
2002 · Julie Lotharius, Patrik Brundin · Nature reviews. Neuroscience · 1,325
Oxidative stress and inflammation in Parkinson's disease: is there a causal link?
2005 · Andreas Hald, Julie Lotharius · Experimental Neurology · 513
Distinct Mechanisms Underlie Neurotoxin-Mediated Cell Death in Cultured Dopaminergic Neurons
1999 · Julie Lotharius, Laura L. Dugan, et al. · Journal of Neuroscience · 405
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A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria
2015 · Margaret A. Phillips, Julie Lotharius, et al. · Science Translational Medicine · 394
Effect of Mutant α-Synuclein on Dopamine Homeostasis in a New Human Mesencephalic Cell Line
2002 · Julie Lotharius, Sebastian Barg, et al. · Journal of Biological Chemistry · 369
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Fullerene-based antioxidants and neurodegenerative disorders
2001 · L.L. Dugan, E.G. Lovett, et al. · Parkinsonism & Related Disorders · 339
The Parkinsonism-inducing Drug 1-Methyl-4-phenylpyridinium Triggers Intracellular Dopamine Oxidation
2000 · Julie Lotharius, Karen L. O'Malley · Journal of Biological Chemistry · 308
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Progressive Degeneration of Human Mesencephalic Neuron-Derived Cells Triggered by Dopamine-Dependent Oxidative Stress Is Dependent on the Mixed-Lineage Kinase Pathway
2005 · Julie Lotharius, Jeppe Falsig, et al. · Journal of Neuroscience · 283
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Impaired dopamine storage resulting from alpha-synuclein mutations may contribute to the pathogenesis of Parkinson's disease
2002 · J. Lotharius, Patrik Brundin · Human Molecular Genetics · 273
Efficacy of small‐molecule glycogen synthase kinase‐3 inhibitors in the postnatal rat model of tau hyperphosphorylation
2007 · M‐L Selenica, H S Jensen, et al. · British Journal of Pharmacology · 138
Safety, tolerability, pharmacokinetics, and activity of the novel long-acting antimalarial DSM265: a two-part first-in-human phase 1a/1b randomised study
2017 · James S McCarthy, Julie Lotharius, et al. · The Lancet Infectious Diseases · 127
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Requirement of a dopaminergic neuronal phenotype for toxicity of low concentrations of 1-methyl-4-phenylpyridinium to human cells
2009 · Stefan Schildknecht, Dominik Pöltl, et al. · Toxicology and Applied Pharmacology · 119
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Vesicular monoamine transporter 2 regulates the sensitivity of rat dopaminergic neurons to disturbed cytosolic dopamine levels
2007 · Sandra Vergo, Jens Leander Johansen, et al. · Brain Research · 93
Evidence for Dysfunction of the Nigrostriatal Pathway in the R6/1 Line of Transgenic Huntington's Disease Mice
2002 · Å. Petersén, Z. Puschban, et al. · Neurobiology of Disease · 91
Specific Modulation of Astrocyte Inflammation by Inhibition of Mixed Lineage Kinases with CEP-1347
2004 · Jeppe Falsig, Peter Pörzgen, et al. · The Journal of Immunology · 71
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Challenges in Antimalarial Drug Discovery
2011 · Jeremy N Burrows, Didier Leroy, et al. · Future Medicinal Chemistry · 67
Targeted expression of BCL-2 attenuates MPP+ but not 6-OHDA induced cell death in dopaminergic neurons
2003 · K O'Malley, Jian Liu, et al. · Neurobiology of Disease · 57
HIF prolyl hydroxylase inhibition increases cell viability and potentiates dopamine release in dopaminergic cells
2010 · Jens Leander Johansen, Thomas Nikolaj Sager, et al. · Journal of Neurochemistry · 51
Repositioning: the fast track to new anti-malarial medicines?
2014 · Julie Lotharius, Francisco Javier Gamo-Benito, et al. · Malaria Journal · 45
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Role of mitochondrial dysfunction and dopamine-dependent oxidative stress in amphetamine-induced toxicity
2001 · Julie Lotharius, Karen L. O'Malley · Annals of Neurology · 43
Inflammation in parkinson’s disease: Causative or epiphenomenal?
2007 · Andreas Hald, Johan van Beek, et al. · Sub-cellular biochemistry/Subcellular biochemistry · 37
In Vitro and In Vivo Activity of Solithromycin (CEM-101) against Plasmodium Species
2011 · Sergio Wittlin, Eric Ekland, et al. · Antimicrobial Agents and Chemotherapy · 22
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A Randomized, Double-Blind, Placebo-Controlled Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Single Enantiomer (+)-Mefloquine Compared with Racemic Mefloquine in Healthy Persons
2010 · Robert Tansley, Julie Lotharius, et al. · American Journal of Tropical Medicine and Hygiene · 22
In vitro and in vivo characterization of the antimalarial lead compound SSJ-183 in Plasmodium models
2013 · Sergio Wittlin, Sarah Schleiferböck, et al. · Drug Design Development and Therapy · 14
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[Free radicals and ailing proteins--the culprits behind Parkinson disease?].
2003 · Ruben Smith, Julie Lotharius, et al. · PubMed · 1
Works count: 26
Citation count: 5,207
H-index: 22
I10-index: 24
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