Author

Dirk Kropeit

Observed names: D Kropeit, D. Kropeit

Institution: AiCuris (Germany)

Observed institutions: AiCuris (Germany), Stadt Mannheim

ORCID: 0000-0003-0356-2052

Observed ORCID: 0000-0003-0356-2052

OpenAlex ID: A5020698210

Pharmacokinetics and Safety of Letermovir Coadministered With Cyclosporine A or Tacrolimus in Healthy Subjects

2017 · Dirk Kropeit, Oliver von Richter, et al. · Clinical Pharmacology in Drug Development · 84

Discovery, Chemistry, and Preclinical Development of Pritelivir, a Novel Treatment Option for Acyclovir-Resistant Herpes Simplex Virus Infections

2022 · Alexander Birkmann, Susanne Bonsmann, et al. · Journal of Medicinal Chemistry · 60

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Pharmacokinetics and safety of letermovir, a novel anti‐human cytomegalovirus drug, in patients with renal impairment

2017 · Dirk Kropeit, Jürgen Scheuenpflug, et al. · British Journal of Clinical Pharmacology · 37

Intravenous Hydroxypropyl β‐Cyclodextrin Formulation of Letermovir: A Phase I, Randomized, Single‐Ascending, and Multiple‐Dose Trial

2017 · K Erb‐Zohar, D Kropeit, et al. · Clinical and Translational Science · 31

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Pharmacokinetics and safety of the anti‐human cytomegalovirus drug letermovir in subjects with hepatic impairment

2017 · Dirk Kropeit, David McCormick, et al. · British Journal of Clinical Pharmacology · 30

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Lacosamide cardiac safety: a thorough QT/QTc trial in healthy volunteers

2015 · D. Kropeit, M. Johnson, et al. · Acta Neurologica Scandinavica · 29

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Absorption, Metabolism, Distribution, and Excretion of Letermovir

2021 · Karsten Menzel, Prajakti Kothare, et al. · Current Drug Metabolism · 20

Pharmacokinetics-Pharmacodynamics of the Helicase-Primase Inhibitor Pritelivir following Treatment of Wild-Type or Pritelivir-Resistant Virus Infection in a Murine Herpes Simplex Virus 1 Infection Model

2014 · Subhajit Biswas, Soumi Sukla, et al. · Antimicrobial Agents and Chemotherapy · 20

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First‐in‐Human, Single‐ and Multiple‐Ascending‐Dose, Food‐Effect, and Absolute Bioavailability Trials to Assess the Pharmacokinetics, Safety, and Tolerability of Pritelivir, a Nonnucleoside Helicase‐Primase Inhibitor Against Herpes Simplex Virus in Healthy Subjects

2023 · Dirk Kropeit, Susanne Bonsmann, et al. · Clinical Pharmacology in Drug Development · 18

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Pharmacokinetics and Safety of Letermovir and Midazolam Coadministration in Healthy Subjects

2021 · Dirk Kropeit, David McCormick, et al. · Clinical Pharmacology in Drug Development · 12

Mass Balance and Metabolite Profile after Single and Multiple Oral Doses of Pritelivir in Healthy Subjects

2024 · Susanne Bonsmann, David McCormick, et al. · Clinical Pharmacology in Drug Development · 10

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FRI-199-First in Human, single ascending dose clinical trial of AIC649 in patients with chronic hepatitis

2019 · Ibironke Addy, Alen Jambrecina, et al. · Journal of Hepatology · 10

The Effect of Oral Letermovir Administration on the Pharmacokinetics of a Single Oral Dose of P‐Glycoprotein Substrate Digoxin in Healthy Volunteers

2021 · Jürgen Scheuenpflug, Dirk Kropeit, et al. · Clinical Pharmacology in Drug Development · 7

Low drug-interaction potential of Lacosamide

2005 · D. Kropeit, B. Koch, et al. · Journal of Pain · 6

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Evaluation of the Clinical Drug‐Drug Interaction Potential of Pritelivir on Transporters and CYP450 Enzymes Using a Cocktail Approach

2024 · Michiel de Vries, Susanne Bonsmann, et al. · Clinical Pharmacology in Drug Development · 5

Safety and Human Pharmacokinetics of AIC316, a Potent Helicase-Primase Inhibitor of Herpes Simplex Virus (HSV)

2011 · Alexander Birkmann, Dirk Kropeit, et al. · Antiviral Research · 5

(851)

2006 · D. Kropeit, U. Scharfenecker, et al. · Journal of Pain · 5

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Overview on Clinical Trials and Resistance Breaking Activity of the Anti-Cytomegalovirus Compound AIC246

2010 · Holger Zimmermann, Susanne Stoelben, et al. · Antiviral Research · 2

Effect of Renal and Hepatic Impairment on the Pharmacokinetics of Pritelivir and Its Metabolites

2024 · Katharina Erb‐Zohar, Susanne Bonsmann, et al. · Clinical Pharmacology in Drug Development · 1

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(850)

2006 · B. Schiltmeyer, D. Kropeit, et al. · Journal of Pain · 1

Safety and Pharmacokinetics in Healthy Volunteers Following Single and Multiple Ascending Doses of AIC468, a Novel Antisense Oligonucleotide Targeting BK-Virus Transcripts

2026 · D. Kropeit · American Journal of Transplantation

P-113. Interim Results of the First-in-human Phase 1 Trial of AIC468: A Novel Antisense Oligonucleotide that Targets BK-Virus Transcripts

2026 · Susanne Bonsmann, Ashish Soman, et al. · Open Forum Infectious Diseases

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P3.446 Excellent Efficacy of PRITELIVIR (AIC316) in Suppression of Genital Herpes, a Novel Drug Against Herpes Simplex Virus (HSV) Type 1 and 2

2013 · A Birkmann, D McCormick, et al. · Sexually Transmitted Infections

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2.P.243 Self-reported physical activity in healthy children is correlated with cardiovascular risk factors

1997 · U. Querfeld, D. Kropeit, et al. · Atherosclerosis

Works count: 24

Citation count: 393

H-index: 10

I10-index: 12