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Mercedes Segovia

Targeting TMEM176B Enhances Antitumor Immunity and Augments the Efficacy of Immune Checkpoint Blockers by Unleashing Inflammasome Activation
2019 · Mercedes Segovia, Sofia Russo, et al. · Cancer Cell · 160
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Fragmentation of extracellular ribosomes and tRNAs shapes the extracellular RNAome
2020 · Juan Pablo Tosar, Mercedes Segovia, et al. · Nucleic Acids Research · 107
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Autologous Dendritic Cells Prolong Allograft Survival Through Tmem176b-Dependent Antigen Cross-Presentation
2014 · M. Segovia, C. Louvet, et al. · American Journal of Transplantation · 88
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Ivermectin reduces in vivo coronavirus infection in a mouse experimental model
2021 · A. P. Arévalo, R. Pagotto, et al. · Scientific Reports · 73
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Cell Therapy With Autologous Tolerogenic Dendritic Cells Induces Allograft Tolerance Through Interferon-Gamma and Epstein-Barr Virus-Induced Gene 3
2011 · M. Hill, P. Thebault, et al. · American Journal of Transplantation · 70
Tolerogenic dendritic cells and negative vaccination in transplantation: from rodents to clinical trials
2012 · Aurélie Moreau, Emilie Varey, et al. · Frontiers in Immunology · 62
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Comparative Study of the Immunoregulatory Capacity of In Vitro Generated Tolerogenic Dendritic Cells, Suppressor Macrophages, and Myeloid-Derived Suppressor Cells
2016 · Laura Carretero-Iglesia, Laurence Bouchet-Delbos, et al. · Transplantation · 41
Generation and in vivo evaluation of IL10-treated dendritic cells in a nonhuman primate model of AAV-based gene transfer
2014 · Aurélie Moreau, Céline Vandamme, et al. · Molecular Therapy — Methods & Clinical Development · 28
PD-1/PD-L1 blockade abrogates a dysfunctional innate-adaptive immune axis in critical β-coronavirus disease
2022 · Maite Duhalde Vega, Daniela Olivera, et al. · Science Advances · 26
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The Paradoxical Roles of Inflammation during PD-1 Blockade in Cancer
2020 · Marcelo Hill, Mercedes Segovia, et al. · Trends in Immunology · 26
Preparation of Mouse Bone Marrow-Derived Dendritic Cells with Immunoregulatory Properties
2010 · Mercedes Segovia, Maria Cristina Cuturi, et al. · Methods in molecular biology · 26
The intracellular cation channel TMEM176B as a dual immunoregulator
2022 · Marcelo Hill, Sofía Russo, et al. · Frontiers in Cell and Developmental Biology · 23
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Role of inflammasome activation in tumor immunity triggered by immune checkpoint blockers
2020 · M Segovia, S Russo, et al. · Clinical & Experimental Immunology · 17
Penicillin Binding Proteins as Danger Signals: Meningococcal Penicillin Binding Protein 2 Activates Dendritic Cells through Toll-Like Receptor 4
2011 · Marcelo Hill, Ala-Eddine Deghmane, et al. · PLoS ONE · 15
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Ribonuclease activity undermines immune sensing of naked extracellular RNA
2025 · Mauricio Castellano, Valentina Blanco, et al. · Cell Genomics · 13
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Formulating a TMEM176B Blocker in Chitosan Nanoparticles Uncouples its Paradoxical Roles in Innate and Adaptive Antitumoral Immunity
2022 · Sabina Victoria, Analía Castro, et al. · International Journal of Biological Macromolecules · 11
Immune-driven gene expression loss following intramuscular AAV delivery to non-human primates is only transient
2025 · Malo Journou, Marie Devaux, et al. · Molecular Therapy — Methods & Clinical Development · 6
What is the Role of Antigen-Processing Mechanisms in Autologous Tolerogenic Dendritic Cell Therapy in Organ Transplantation?
2011 · Marcelo Hill, Mercedes Segovia, et al. · Immunotherapy · 3
Activation of the Immunoregulatory Cation Channel TMEM176B by a Nitroalkene Derivative of Salicylate Prolongs Graft Survival
2025 · Germán Galliussi, Javier Noboa, et al. · Transplantation · 1
Loss-of-function variant of the immunoregulator TMEM176B is associated with progression to ESKD in SLE
2026 · Daniela Olivera, Jonathan Campos-Guzmán, et al. · Lupus Science & Medicine
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Reverse Phase HPLC Methodology for the Determination of Bay K8644
2024 · Pablo Miranda, Analía Castro, et al. · Journal of Chromatographic Science
Abstract 1412: Immune and metabolic control of Th17 cells by TMEM176B: Potential implication in cancer immunotherapy
2024 · Sofia Russo, Mateo Malcuori, et al. · Cancer Research
Abstract 5116: Inflammasome unleashing during anti-PD-1 therapy modulates CD8+ T cell exhaustion through Th17 cells
2023 · Sofia Russo, Mateo Malcuori, et al. · Cancer Research
A Critical Role for Graft Passenger Leukocytes in Donor-Specific Allograft Tolerance Induced by Autologous Tolerogenic Dendritic Cells
2012 · M. Segovia, P. Thebault, et al. · Transplantation
T.1. IFN-γ and Graft-derived Donor Antigens are Critical for Autologous DC-induced Tolerance: A Role for Double Negative Treg and EBI3
2009 · Marcelo Hill, Pamela Thebault, et al. · Clinical Immunology
Works count: 25
Citation count: 796
H-index: 14
I10-index: 16
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