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Themis Thoudam

Oxidative stress and calcium dysregulation by palmitate in type 2 diabetes
2017 · Luong Dai Ly, Shanhua Xu, et al. · Experimental & Molecular Medicine · 378
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Split-TurboID enables contact-dependent proximity labeling in cells
2020 · Kelvin F. Cho, Tess C. Branon, et al. · Proceedings of the National Academy of Sciences · 355
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PDK4 Augments ER–Mitochondria Contact to Dampen Skeletal Muscle Insulin Signaling During Obesity
2018 · Themis Thoudam, Chae-Myeong Ha, et al. · Diabetes · 207
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Role of the Pyruvate Dehydrogenase Complex in Metabolic Remodeling: Differential Pyruvate Dehydrogenase Complex Functions in Metabolism
2018 · Sungmi Park, Jae-Han Jeon, et al. · Diabetes & Metabolism Journal · 184
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The Role of Pyruvate Metabolism in Mitochondrial Quality Control and Inflammation
2023 · Min-Ji Kim, Hoyul Lee, et al. · Molecules and Cells · 96
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ApoE4-dependent lysosomal cholesterol accumulation impairs mitochondrial homeostasis and oxidative phosphorylation in human astrocytes
2023 · Hyein Lee, Sukhee Cho, et al. · Cell Reports · 93
Cell-to-cell and organ-to-organ crosstalk in the pathogenesis of alcohol-associated liver disease
2024 · Hui Gao, Yanchao Jiang, et al. · eGastroenterology · 90
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Role of Mitochondria-Associated Endoplasmic Reticulum Membrane in Inflammation-Mediated Metabolic Diseases
2016 · Themis Thoudam, Jae-Han Jeon, et al. · Mediators of Inflammation · 87
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Inhibition of pyruvate dehydrogenase kinase 4 ameliorates kidney ischemia-reperfusion injury by reducing succinate accumulation during ischemia and preserving mitochondrial function during reperfusion
2023 · Chang Joo Oh, Min-Ji Kim, et al. · Kidney International · 82
Low-Dose Persistent Organic Pollutants Impair Insulin Secretory Function of Pancreatic β-Cells: Human and In Vitro Evidence
2017 · Yu-Mi Lee, Chae-Myeong Ha, et al. · Diabetes · 74
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Serum Metabolomic Profiling Identifies Key Metabolic Signatures Associated With Pathogenesis of Alcoholic Liver Disease in Humans
2019 · Zhihong Yang, Praveen Kusumanchi, et al. · Hepatology Communications · 73
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Enhanced Ca2+-channeling complex formation at the ER-mitochondria interface underlies the pathogenesis of alcohol-associated liver disease
2023 · Themis Thoudam, Dipanjan Chanda, et al. · Nature Communications · 68
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Loss of metabolic flexibility as a result of overexpression of pyruvate dehydrogenase kinases in muscle, liver and the immune system: Therapeutic targets in metabolic diseases
2020 · Jae‐Han Jeon, Themis Thoudam, et al. · Journal of Diabetes Investigation · 60
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Noncanonical PDK4 action alters mitochondrial dynamics to affect the cellular respiratory status
2022 · Themis Thoudam, Dipanjan Chanda, et al. · Proceedings of the National Academy of Sciences · 51
Pyruvate dehydrogenase kinase 4 promotes ubiquitin–proteasome system‐dependent muscle atrophy
2022 · Ibotombi Singh Sinam, Dipanjan Chanda, et al. · Journal of Cachexia Sarcopenia and Muscle · 41
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Mitochondrial quality control in alcohol-associated liver disease
2024 · Themis Thoudam, Hui Gao, et al. · Hepatology Communications · 34
Inhibition of Pyruvate Dehydrogenase Kinase 4 in CD4+ T Cells Ameliorates Intestinal Inflammation
2022 · Hoyul Lee, Jae Han Jeon, et al. · Cellular and Molecular Gastroenterology and Hepatology · 31
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Alcohol-induced gut microbial reorganization and associated overproduction of phenylacetylglutamine promotes cardiovascular disease
2024 · Zhen Li, Min Gu, et al. · Nature Communications · 26
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Inhibitory Regulation of FOXO1 in PPARδ Expression Drives Mitochondrial Dysfunction and Insulin Resistance
2024 · Soyoung Park, Hye-Na Cha, et al. · Diabetes · 18
Upregulation of the ERRγ–VDAC1 axis underlies the molecular pathogenesis of pancreatitis
2023 · Dipanjan Chanda, Themis Thoudam, et al. · Proceedings of the National Academy of Sciences · 16
Gossypetin Prevents the Progression of Nonalcoholic Steatohepatitis by Regulating Oxidative Stress and AMP-Activated Protein Kinase
2023 · Eunji Oh, Jae Lee, et al. · Molecular Pharmacology · 12
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Silencing FAF2 mitigates alcohol-induced hepatic steatosis by modulating lipolysis and PCSK9 pathway
2025 · Nazmul Huda, Praveen Kusumanchi, et al. · Hepatology Communications · 9
Inhibition of the mitochondrial permeability transition pore as a promising target for protecting auditory function in cisplatin-induced hearing loss
2024 · Ye-Ri Kim, Sujin Jun, et al. · Biomedicine & Pharmacotherapy · 7
LncRNA H19 promoted alcohol-associated liver disease through dysregulation of alternative splicing and methionine metabolism
2024 · Zhihong Yang, Yanchao Jiang, et al. · Hepatology · 6
Unique urine and serum metabolomic signature in patients with excessive alcohol use: An exploratory study
2024 · Zhihong Yang, Hui Gao, et al. · Alcoholism Clinical and Experimental Research · 6
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Works count: 36
Citation count: 2,117
H-index: 18
I10-index: 21
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