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Matthias Gehringer
Observed names:
Gehringer, M.,
Gehringer, Matthias,
M Gehringer,
M. Gehringer
Institution:
University of Tübingen
Observed institutions:
École Nationale Supérieure de Chimie de Montpellier,
Centre National de la Recherche Scientifique,
ETH Zurich,
Institut Charles Gerhardt Montpellier,
Institute of Pharmaceutical Sciences,
University of Tübingen
show all 6
ORCID:
0000-0003-0163-3419
Observed ORCID:
0000-0003-0163-3419
OpenAlex ID:
A5021605039
Emerging and Re-Emerging Warheads for Targeted Covalent Inhibitors: Applications in Medicinal Chemistry and Chemical Biology
2018
·
Matthias Gehringer
, Stefan A. Laufer
·
Journal of Medicinal Chemistry
·
774
Emerging and Re-emerging Warheads for Targeted Covalent Inhibitors: An Update
2024
·
Laura Hillebrand
, Xiaojun Julia Liang
, et al.
·
Journal of Medicinal Chemistry
·
226
Selective JAK3 Inhibitors with a Covalent Reversible Binding Mode Targeting a New Induced Fit Binding Pocket
2016
·
Michael Forster
, Apirat Chaikuad
, et al.
·
Cell chemical biology
·
133
PDF
Inhibitors of c-Jun N-Terminal Kinases: An Update
2014
·
Pierre Koch
, Matthias Gehringer
, et al.
·
Journal of Medicinal Chemistry
·
103
The Macrolide Toxin Mycolactone Promotes Bim-Dependent Apoptosis in Buruli Ulcer through Inhibition of mTOR
2017
·
Raphael Bieri
, Nicole Scherr
, et al.
·
ACS Chemical Biology
·
84
Development, Optimization, and Structure–Activity Relationships of Covalent-Reversible JAK3 Inhibitors Based on a Tricyclic Imidazo[5,4-d]pyrrolo[2,3-b]pyridine Scaffold
2018
·
Michael Forster
, Apirat Chaikuad
, et al.
·
Journal of Medicinal Chemistry
·
64
Demystifying Functional Parameters for Irreversible Enzyme Inhibitors
2024
·
David E. Heppner
, Blessing C. Ogboo
, et al.
·
Journal of Medicinal Chemistry
·
62
PDF
c-JunN-terminal kinase inhibitors: a patent review (2010 – 2014)
2015
·
Matthias Gehringer
, Felix Muth
, et al.
·
Expert Opinion on Therapeutic Patents
·
57
Silica-supported l-proline organocatalysts for asymmetric aldolisation
2009
·
Alexandra Zamboulis
, Nicolas J. Rahier
, et al.
·
Tetrahedron Asymmetry
·
49
Developing Small‐Molecule Inhibitors of HECT‐Type Ubiquitin Ligases for Therapeutic Applications: Challenges and Opportunities
2018
·
Dan Chen
, Matthias Gehringer
, et al.
·
ChemBioChem
·
43
PDF
Recent advances in JAK3 inhibition: Isoform selectivity by covalent cysteine targeting
2017
·
Michael Forster
, Matthias Gehringer
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
43
Covalent Inhibitors: Back on track?
2020
·
Matthias Gehringer
·
Future Medicinal Chemistry
·
40
The chemistry and biology of mycolactones
2017
·
Matthias Gehringer
, Karl-Heinz Altmann
·
Beilstein Journal of Organic Chemistry
·
38
PDF
Design and Synthesis of Tricyclic JAK3 Inhibitors with Picomolar Affinities as Novel Molecular Probes
2014
·
Matthias Gehringer
, Ellen Pfaffenrot
, et al.
·
ChemMedChem
·
38
Development of the First Covalent Monopolar Spindle Kinase 1 (MPS1/TTK) Inhibitor
2022
·
Ricardo A. M. Serafim
, André da Silva Santiago
, et al.
·
Journal of Medicinal Chemistry
·
35
Covalent chemical probes for protein kinases
2023
·
Ricardo A.M. Serafim
, Lisa Haarer
, et al.
·
Current Research in Chemical Biology
·
34
Click Chemistry: Novel Applications in Cell Biology and Drug Discovery
2017
·
Matthias Gehringer
, Stefan A. Laufer
·
Angewandte Chemie International Edition
·
34
Novel Hinge‐Binding Motifs for Janus Kinase 3 Inhibitors: A Comprehensive Structure–Activity Relationship Study on Tofacitinib Bioisosteres
2014
·
Matthias Gehringer
, Michael Forster
, et al.
·
ChemMedChem
·
33
Development of Highly Potent and Selective Covalent FGFR4 Inhibitors Based on S N Ar Electrophiles
2024
·
Moritz Schwarz
, Maksym Kurkunov
, et al.
·
Journal of Medicinal Chemistry
·
32
PDF
Chemical Probes for Understudied Kinases: Challenges and Opportunities
2021
·
Ricardo A. M. Serafim
, Jonathan M. Elkins
, et al.
·
Journal of Medicinal Chemistry
·
32
PDF
Gefitinib-Tamoxifen Hybrid Ligands as Potent Agents against Triple-Negative Breast Cancer
2022
·
Carine M. Abdelmalek
, Zexi Hu
, et al.
·
Journal of Medicinal Chemistry
·
31
Discovery of a Novel Class of Covalent Dual Inhibitors Targeting the Protein Kinases BMX and BTK
2020
·
Michael Forster
, Xiaojun Julia Liang
, et al.
·
International Journal of Molecular Sciences
·
31
Discovery of a Potent and Highly Isoform-Selective Inhibitor of the Neglected Ribosomal Protein S6 Kinase Beta 2 (S6K2)
2021
·
Stefan Gerstenecker
, Lisa Haarer
, et al.
·
Cancers
·
28
PDF
Nocathioamides, Uncovered by a Tunable Metabologenomic Approach, Define a Novel Class of Chimeric Lanthipeptides
2021
·
Hamada Saad
, Saefuddin Aziz
, et al.
·
Angewandte Chemie International Edition
·
27
PDF
Covalent Kinase Inhibitors: An Overview
2020
·
Matthias Gehringer
·
Topics in medicinal chemistry
·
25
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Works count:
86
Citation count:
2,379
H-index:
25
I10-index:
36
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