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Simon Thomas

Observed names: S Thomas, S. Thomas, Thomas, Simon
ORCID: 0000-0002-9979-081X
Observed ORCID: 0000-0002-9979-081X
OpenAlex ID: A5021669399
Application of a Generic Physiologically Based Pharmacokinetic Model to the Estimation of Xenobiotic Levels in Rat Plasma
2005 · F.A. Brightman, D.E. Leahy, et al. · Drug Metabolism and Disposition · 67
Simulation Modelling of Human Intestinal Absorption using Caco-2 Permeability and Kinetic Solubility Data for Early Drug Discovery
2008 · Simon Thomas, Frances Brightman, et al. · Journal of Pharmaceutical Sciences · 59
Application of a Generic Physiologically Based Pharmacokinetic Model to the Estimation of Xenobiotic Levels in Human Plasma
2005 · F.A. Brightman, D.E. Leahy, et al. · Drug Metabolism and Disposition · 53
SCREENED: A Multistage Model of Thyroid Gland Function for Screening Endocrine-Disrupting Chemicals in a Biologically Sex-Specific Manner
2020 · Lorenzo Moroni, Fulvio Barbaro, et al. · International Journal of Molecular Sciences · 24
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The novel fungal CYP51 inhibitor VT-1598 displays classic dose-dependent antifungal activity in murine models of invasive aspergillosis
2019 · E P Garvey, A D Sharp, et al. · Medical Mycology · 20
Physiologically-based Simulation Modelling for the Reduction of Animal Use in the Discovery of Novel Pharmaceuticals
2009 · Simon Thomas · Alternatives to Laboratory Animals · 17
Challenges in the prediction and modeling of oral absorption and bioavailability.
2010 · Paul D Metcalfe, Simon Thomas · PubMed · 11
A physiome interoperability roadmap for personalized drug development
2016 · Simon Thomas, Katherine Wolstencroft, et al. · Interface Focus · 8
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Clinical relevance of predictive physiologically based pharmacokinetic methods
2008 · Simon Thomas · Expert Opinion on Drug Discovery · 5
In SilicoModels of Drug Metabolism and Drug Interactions
2012 · Richard J. Dimelow, Paul D. Metcalfe, et al. · Encyclopedia of Drug Metabolism and Interactions · 4
Physiologically-based Pharmacokinetic Modelling for the Reduction of Animal Use in the Discovery of Novel Pharmaceuticals
2010 · Simon Thomas · Alternatives to Laboratory Animals · 3
Causes and management of drug‐induced angioedema
2006 · Isam Salih, Simon Thomas · Prescriber · 3
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Prediction of Phosphoglycoprotein (P‐gp)‐Mediated Disposition in Early Drug Discovery
2014 · Simon Thomas, Richard J. Dimelow · Methods and principles in medicinal chemistry · 2
Chapter 7. The Characteristics, Validation and Applications of In silico and In vitro Models of Drug Transporters
2016 · Pradeep Sharma, Mohammed I. Atari, et al. · Royal Society of Chemistry eBooks · 1
Filtering toxicity from the pipeline: The role of high content toxicology in early identification of toxic liabilities
2011 · S. Thomas, P. Metcalfe, et al. · Toxicology Letters · 1
Microphysiological Flow Batteries For Dynamic EDC Screening Of mESC-derived Thyroid Organoids
2026 · Anna M. Kip, Daniel J. Carvalho, et al. · SSRN Electronic Journal
Chapter 9. Mechanistic Modelling to Predict Transporter-mediated Drug Disposition and Drug–Drug Interactions
2016 · Rui Li, Krishna K. Machavaram, et al. · Royal Society of Chemistry eBooks
An in silico model to predict renal clearance of xenobiotics in humans
2015 · M. Atari, S. Thomas · Toxicology Letters
Works count: 19
Citation count: 278
H-index: 8
I10-index: 7
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