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Hiroki Tsumoto

Identification of Cell-Active Lysine Specific Demethylase 1-Selective Inhibitors
2009 · Rie Ueda, Takayoshi Suzuki, et al. · Journal of the American Chemical Society · 189
Design, Synthesis, Enzyme-Inhibitory Activity, and Effect on Human Cancer Cells of a Novel Series of Jumonji Domain-Containing Protein 2 Histone Demethylase Inhibitors
2010 · Shohei Hamada, Takayoshi Suzuki, et al. · Journal of Medicinal Chemistry · 162
Rapid Discovery of Highly Potent and Selective Inhibitors of Histone Deacetylase 8 Using Click Chemistry to Generate Candidate Libraries
2012 · Takayoshi Suzuki, Yosuke Ota, et al. · Journal of Medicinal Chemistry · 159
Synthesis and activity of N-oxalylglycine and its derivatives as Jumonji C-domain-containing histone lysine demethylase inhibitors
2009 · Shohei Hamada, Tae-Dong Kim, et al. · Bioorganic & Medicinal Chemistry Letters · 125
Photoinduced Nitric Oxide Release from a Hindered Nitrobenzene Derivative by Two-Photon Excitation
2009 · Kazuhiro Hishikawa, Hidehiko Nakagawa, et al. · Journal of the American Chemical Society · 105
Integrin β4 and vinculin contained in exosomes are potential markers for progression of prostate cancer associated with taxane-resistance
2015 · KYOJIRO KAWAKAMI, YASUNORI FUJITA, et al. · International Journal of Oncology · 99
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Short‐chain fatty acid receptor GPR41‐mediated activation of sympathetic neurons involves synapsin 2b phosphorylation
2012 · Daisuke Inoue, Ikuo Kimura, et al. · FEBS Letters · 99
S-nitrosylation regulates mitochondrial quality control via activation of parkin
2013 · Kentaro Ozawa, Akira T. Komatsubara, et al. · Scientific Reports · 95
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Differentiation of Sialyl Linkage Isomers by One-Pot Sialic Acid Derivatization for Mass Spectrometry-Based Glycan Profiling
2017 · Takashi Nishikaze, Hiroki Tsumoto, et al. · Analytical Chemistry · 94
Lysine‐Specific Demethylase 1‐Selective Inactivators: Protein‐Targeted Drug Delivery Mechanism
2013 · Daisuke Ogasawara, Yukihiro Itoh, et al. · Angewandte Chemie International Edition · 79
An Unexpected Example of Protein‐Templated Click Chemistry
2010 · Takayoshi Suzuki, Yosuke Ota, et al. · Angewandte Chemie International Edition · 77
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Design, Synthesis, and Biological Activity of Boronic Acid-Based Histone Deacetylase Inhibitors
2009 · Nobuaki Suzuki, Takayoshi Suzuki, et al. · Journal of Medicinal Chemistry · 77
Potent mechanism-based sirtuin-2-selective inhibition by an in situ-generated occupant of the substrate-binding site, “selectivity pocket” and NAD + -binding site
2017 · Paolo Mellini, Yukihiro Itoh, et al. · Chemical Science · 74
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Inhibition of Human Sirtuins by in Situ Generation of an Acetylated Lysine−ADP−Ribose Conjugate
2009 · Tomomi Asaba, Takayoshi Suzuki, et al. · Journal of the American Chemical Society · 62
Excess APP O -glycosylation by GalNAc-T6 decreases Aβ production
2016 · Keiko Akasaka-Manya, Masaki Kawamura, et al. · The Journal of Biochemistry · 48
Identification of a cell-active non-peptide sirtuin inhibitor containing N-thioacetyl lysine
2009 · Takayoshi Suzuki, Tomomi Asaba, et al. · Bioorganic & Medicinal Chemistry Letters · 45
DJ-1 is indispensable for the S-nitrosylation of Parkin, which maintains function of mitochondria
2020 · Kentaro Ozawa, Hiroki Tsumoto, et al. · Scientific Reports · 42
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Heat Resistant Characteristics of Major Royal Jelly Protein 1 (MRJP1) Oligomer
2015 · Takanori Moriyama, Aimi Ito, et al. · PLoS ONE · 41
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Alternative photoinduced release of HNO or NO from an acyl nitroso compound, depending on environmental polarity
2010 · Kazuya Matsuo, Hidehiko Nakagawa, et al. · Chemical Communications · 38
Design, synthesis, enzyme inhibition, and tumor cell growth inhibition of 2-anilinobenzamide derivatives as SIRT1 inhibitors
2009 · Takayoshi Suzuki, Keiko Imai, et al. · Bioorganic & Medicinal Chemistry · 38
Crystal structures of fukutin-related protein (FKRP), a ribitol-phosphate transferase related to muscular dystrophy
2020 · Naoyuki Kuwabara, Rieko Imae, et al. · Nature Communications · 35
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Contribution of the exosome-associated form of secreted endoplasmic reticulum aminopeptidase 1 to exosome-mediated macrophage activation
2018 · Yoshikuni Goto, Yuko Ogawa, et al. · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · 35
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Identification of SNAIL1 Peptide-Based Irreversible Lysine-Specific Demethylase 1-Selective Inactivators
2015 · Yukihiro Itoh, Keisuke Aihara, et al. · Journal of Medicinal Chemistry · 34
Change in N-Glycosylation of Plasma Proteins in Japanese Semisupercentenarians
2015 · Yuri Miura, Noritaka Hashii, et al. · PLoS ONE · 31
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CDP-glycerol inhibits the synthesis of the functional O-mannosyl glycan of α-dystroglycan
2018 · Rieko Imae, Hiroshi Manya, et al. · Journal of Biological Chemistry · 30
Works count: 82
Citation count: 2,540
H-index: 27
I10-index: 54
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