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Sylvain Arnould

Multiplex Genome-Edited T-cell Manufacturing Platform for “Off-the-Shelf” Adoptive T-cell Immunotherapies
2015 · Laurent Poirot, Brian Philip, et al. · Cancer Research · 602
Genome-edited, donor-derived allogeneic anti-CD19 chimeric antigen receptor T cells in paediatric and adult B-cell acute lymphoblastic leukaemia: results of two phase 1 studies
2020 · Reuben Benjamin, Reuben Benjamin, et al. · The Lancet · 369
A combinatorial approach to create artificial homing endonucleases cleaving chosen sequences
2006 · Julianne Smith, Sylvestre Grizot, et al. · Nucleic Acids Research · 329
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Engineering of Large Numbers of Highly Specific Homing Endonucleases that Induce Recombination on Novel DNA Targets
2005 · Sylvain Arnould, Patrick Chames, et al. · Journal of Molecular Biology · 191
Molecular basis of xeroderma pigmentosum group C DNA recognition by engineered meganucleases
2008 · Pilar Redondo, Jesús Prieto, et al. · Nature · 153
Engineered I-CreI Derivatives Cleaving Sequences from the Human XPC Gene can Induce Highly Efficient Gene Correction in Mammalian Cells
2007 · Sylvain Arnould, Christophe Perez, et al. · Journal of Molecular Biology · 141
The I-CreI meganuclease and its engineered derivatives: applications from cell modification to gene therapy
2010 · S. Arnould, C. Delenda, et al. · Protein Engineering Design and Selection · 112
Meganuclease-mediated Inhibition of HSV1 Infection in Cultured Cells
2011 · Stéphanie Grosse, Nicolas Huot, et al. · Molecular Therapy · 70
The domain structure of protoporphyrinogen oxidase, the molecular target of diphenyl ether-type herbicides
1998 · Sylvain Arnould, Jean-Michel Camadro · Proceedings of the National Academy of Sciences · 39
A TALEN-Exon Skipping Design for a Bethlem Myopathy Model in Zebrafish
2015 · Zlatko Radev, Jean-Michel Hermel, et al. · PLoS ONE · 30
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The C-terminal loop of the homing endonuclease I-CreI is essential for site recognition, DNA binding and cleavage
2007 · Jesús Prieto, Pilar Redondo, et al. · Nucleic Acids Research · 29
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Acylation stabilizes a protease-resistant conformation of protoporphyrinogen oxidase, the molecular target of diphenyl ether-type herbicides
1999 · Sylvain Arnould, Masayuki Takahashi, et al. · Proceedings of the National Academy of Sciences · 23
Kinetics of Protoporphyrinogen Oxidase Inhibition by Diphenyleneiodonium Derivatives
1997 · Sylvain Arnould, Jean-Luc Berthon, et al. · Biochemistry · 19
Monitoring of Nutrients, Metabolites, IgG Titer, and Cell Densities in 10 L Bioreactors Using Raman Spectroscopy and PLS Regression Models
2025 · Morandise Rubini, Julien Boyer, et al. · Pharmaceutics · 11
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Stability of Recombinant Yeast Protoporphyrinogen Oxidase: Effects of Diphenyl Ether-Type Herbicides and Diphenyleneiodonium
1998 · Sylvain Arnould, Masayuki Takahashi, et al. · Biochemistry · 11
Optimizing CAR-T treatment: A T2EVOLVE guide to raw and starting material selection
2024 · Sergio Navarro, Carole Moukheiber, et al. · Molecular Therapy · 9
In Vivo Proof of Concept of Activity and Safety of UCART19, an Allogeneic “Off-the-Shelf” Adoptive T-Cell Immunotherapy Against CD19+ B-Cell Leukemias
2014 · Agnes Gouble, Brian Philip, et al. · Blood · 9
Characteristics of Protoporphyrinogen Oxidase
1999 · Jean-Michel Camadro, Sylvain Arnould, et al. · Springer eBooks · 6
Embedding patient engagement in the R&D process of a life sciences company through co-creation with a patient expert R&D board: a case study
2024 · Estelle Jobson, Marta Garcia, et al. · Research Involvement and Engagement · 4
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Multiplex Genome Editing As a Platform for “Off-the-Shelf” Adoptive CAR T-Cell Immunotherapies
2014 · Sophie Derniame, Hong Zhan, et al. · Blood · 4
UCART19, an allogeneic “off-the-shelf” adoptive T-cell immunotherapy against CD19+ B-cell leukemias.
2015 · Julianne Smith, Laurent Poirot, et al. · Journal of Clinical Oncology · 1
717. UCART19, an Allogeneic “Off-the-Shelf” Adoptive T-Cell Immunotherapy Against CD19+ B-Cell Leukemias
2015 · Laurent Poirot, Brian Philip, et al. · Molecular Therapy · 1
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Treatment of B cells malignancies with anti-CD19 CAR+, TCR-, CD52- allogeneic T cells
2013 · Cécile Schiffer Mannioui, Laëtitia Lemaire, et al. · Journal for ImmunoTherapy of Cancer · 1
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Bio-applications Derived from Site-Directed Genome Modification Technologies
2012 · Christophe Delenda, Sébastien Paris, et al. · Topics in current genetics · 1
Supplementary Figures 1 - 5, Tables 1 - 3 from Multiplex Genome-Edited T-cell Manufacturing Platform for “Off-the-Shelf” Adoptive T-cell Immunotherapies
2023 · Laurent Poirot, Brian Philip, et al.
Works count: 48
Citation count: 2,165
H-index: 13
I10-index: 15
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