Author

Aline Eggenschwiler

Observed name: A. Eggenschwiler

Institution: Molecular Partners (Switzerland)

Observed institutions: University of Zurich, Molecular Partners (Switzerland)

ORCID: 0009-0000-3859-1035

Observed ORCID: 0009-0000-3859-1035

OpenAlex ID: A5021989993

Cullin3-KLHL15 ubiquitin ligase mediates CtIP protein turnover to fine-tune DNA-end resection

2016 · Lorenza P. Ferretti, Sarah-Felicitas Himmels, et al. · Nature Communications · 70

The CD33xCD123xCD70 Multispecific CD3-Engaging DARPin MP0533 Induces Selective T Cell–Mediated Killing of AML Leukemic Stem Cells

2024 · Matteo Bianchi, Christian Reichen, et al. · Cancer Immunology Research · 17

MP0533: A Multispecific Darpin CD3 Engager Targeting CD33, CD123, and CD70 for the Treatment of AML and MDS Designed to Selectively Target Leukemic Stem Cells

2022 · Matteo Bianchi, Christian Reichen, et al. · Blood · 5

Abstract 1890: A solution to T-cell engager toxicity: An anti-CD3 Prodrug DARPin (CD3-PDD) shows no toxicity, but potent anti-tumor activity in a humanized mouse model

2021 · Andreas Bosshart, Julia Katharina Ahlskog, et al. · Cancer Research · 3

MP0621 (cKit x CD16a x CD47), a Multi-Specific Switch-Darpin with Conditional Blockade of CD47 Targeting Hematopoietic Stem Cells: Preclinical Evaluation of a Next-Generation Conditioning Agent for Stem Cell Transplantation

2024 · Alexander Link, Teresa Maria Frasconi, et al. · Blood · 1

Avidity-Engineered CD3 Engaging DARPin ® Targeting Three Tumor Associated Antigens Induce Strong and Specific T Cell Dependent Killing of AML Cells with Potential for Improved Safety

2021 · Matteo Bianchi, Nina Reschke, et al. · Blood · 1

1072 MP0632, a logic-gated conditional Switch-DARPin T cell engager with CD2 co-stimulation enabling selective activity against solid tumors co-expressing MSLN and EpCAM

2026 · Stephan Wullschleger, Matteo Bianchi, et al. · Journal for ImmunoTherapy of Cancer

Abstract 7197: Molecular characteristics of MP0712, a clinical stage 212Pb-based Radio-DARPin candidate for targeted anti-DLL3 radiotherapy of small cell lung cancer (SCLC)

2026 · Stefanie Riesenberg, Amal Saidi, et al. · Cancer Research

Abstract 1624: Logic-gated switch-DARPin T cell engager with CD2 co-stimulation for improved safety and efficacy in MSLN and EpCAM co-expressing ovarian cancer

2026 · Matteo Bianchi, Sarah Jetzer, et al. · Cancer Research

Data from The CD33xCD123xCD70 Multispecific CD3-Engaging DARPin MP0533 Induces Selective T Cell–Mediated Killing of AML Leukemic Stem Cells

2024 · Matteo Bianchi, Christian Reichen, et al.

Supplementary Figure S12 from The CD33xCD123xCD70 Multispecific CD3-Engaging DARPin MP0533 Induces Selective T Cell–Mediated Killing of AML Leukemic Stem Cells

2024 · Matteo Bianchi, Christian Reichen, et al.

Supplementary Figure S1 from The CD33xCD123xCD70 Multispecific CD3-Engaging DARPin MP0533 Induces Selective T Cell–Mediated Killing of AML Leukemic Stem Cells

2024 · Matteo Bianchi, Christian Reichen, et al.

Supplementary Figure S16 from The CD33xCD123xCD70 Multispecific CD3-Engaging DARPin MP0533 Induces Selective T Cell–Mediated Killing of AML Leukemic Stem Cells

2024 · Matteo Bianchi, Christian Reichen, et al.

Supplementary Figure S2 from The CD33xCD123xCD70 Multispecific CD3-Engaging DARPin MP0533 Induces Selective T Cell–Mediated Killing of AML Leukemic Stem Cells

2024 · Matteo Bianchi, Christian Reichen, et al.

Supplementary Figure S15 from The CD33xCD123xCD70 Multispecific CD3-Engaging DARPin MP0533 Induces Selective T Cell–Mediated Killing of AML Leukemic Stem Cells

2024 · Matteo Bianchi, Christian Reichen, et al.

Supplementary Figure S3 from The CD33xCD123xCD70 Multispecific CD3-Engaging DARPin MP0533 Induces Selective T Cell–Mediated Killing of AML Leukemic Stem Cells

2024 · Matteo Bianchi, Christian Reichen, et al.

Supplementary Figure S5 from The CD33xCD123xCD70 Multispecific CD3-Engaging DARPin MP0533 Induces Selective T Cell–Mediated Killing of AML Leukemic Stem Cells

2024 · Matteo Bianchi, Christian Reichen, et al.

Supplementary Figure S13 from The CD33xCD123xCD70 Multispecific CD3-Engaging DARPin MP0533 Induces Selective T Cell–Mediated Killing of AML Leukemic Stem Cells

2024 · Matteo Bianchi, Christian Reichen, et al.

Supplementary Figure S17 from The CD33xCD123xCD70 Multispecific CD3-Engaging DARPin MP0533 Induces Selective T Cell–Mediated Killing of AML Leukemic Stem Cells

2024 · Matteo Bianchi, Christian Reichen, et al.

Supplementary Figure S10 from The CD33xCD123xCD70 Multispecific CD3-Engaging DARPin MP0533 Induces Selective T Cell–Mediated Killing of AML Leukemic Stem Cells

2024 · Matteo Bianchi, Christian Reichen, et al.

Supplementary Figure S14 from The CD33xCD123xCD70 Multispecific CD3-Engaging DARPin MP0533 Induces Selective T Cell–Mediated Killing of AML Leukemic Stem Cells

2024 · Matteo Bianchi, Christian Reichen, et al.

Supplementary Figure S4 from The CD33xCD123xCD70 Multispecific CD3-Engaging DARPin MP0533 Induces Selective T Cell–Mediated Killing of AML Leukemic Stem Cells

2024 · Matteo Bianchi, Christian Reichen, et al.

Supplementary Figure S4 from The CD33xCD123xCD70 Multispecific CD3-Engaging DARPin MP0533 Induces Selective T Cell–Mediated Killing of AML Leukemic Stem Cells

2024 · Matteo Bianchi, Christian Reichen, et al.

Supplementary Figure S18 from The CD33xCD123xCD70 Multispecific CD3-Engaging DARPin MP0533 Induces Selective T Cell–Mediated Killing of AML Leukemic Stem Cells

2024 · Matteo Bianchi, Christian Reichen, et al.

Supplementary Table S9 from The CD33xCD123xCD70 Multispecific CD3-Engaging DARPin MP0533 Induces Selective T Cell–Mediated Killing of AML Leukemic Stem Cells

2024 · Matteo Bianchi, Christian Reichen, et al.

Works count: 41

Citation count: 97

H-index: 3

I10-index: 2