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Xuguang Tai
Observed names:
X G Tai,
Xu-Guang Tai,
Xu‐Guang Tai
Institutions:
National Institutes of Health,
National Cancer Institute
Observed institutions:
National Institutes of Health,
National Cancer Institute,
National Cancer Institute,
National Cancer Institute,
Center for Cancer Research,
The University of Osaka
show all 6
ORCID:
0000-0001-5322-7127
Observed ORCID:
0000-0001-5322-7127
OpenAlex ID:
A5022645169
CD28 costimulation of developing thymocytes induces Foxp3 expression and regulatory T cell differentiation independently of interleukin 2
2005
·
Xuguang Tai
, Michelle Cowan
, et al.
·
Nature Immunology
·
614
Glutamine-dependent α-ketoglutarate production regulates the balance between T helper 1 cell and regulatory T cell generation
2015
·
Dorota Klysz
, Xuguang Tai
, et al.
·
Science Signaling
·
520
Response to RAG-Mediated V(D)J Cleavage by NBS1 and γ-H2AX
2000
·
Hua Tang Chen
, Avinash Bhandoola
, et al.
·
Science
·
318
Basis of CTLA-4 function in regulatory and conventional CD4+ T cells
2012
·
Xuguang Tai
, François Van Laethem
, et al.
·
Blood
·
251
PDF
Foxp3 Transcription Factor Is Proapoptotic and Lethal to Developing Regulatory T Cells unless Counterbalanced by Cytokine Survival Signals
2013
·
Xuguang Tai
, Batu Erman
, et al.
·
Immunity
·
219
PDF
Clonal deletion and the fate of autoreactive thymocytes that survive negative selection
2012
·
Leonid A Pobezinsky
, Georgi S Angelov
, et al.
·
Nature Immunology
·
179
PDF
Deletion of CD4 and CD8 Coreceptors Permits Generation of αβT Cells that Recognize Antigens Independently of the MHC
2007
·
François Van Laethem
, Sophia D. Sarafova
, et al.
·
Immunity
·
173
PDF
Non-CD28 Costimulatory Molecules Present in T Cell Rafts Induce T Cell Costimulation by Enhancing the Association of TCR with Rafts
2000
·
Yumi Yashiro-Ohtani
, Xu-Yu Zhou
, et al.
·
The Journal of Immunology
·
151
PDF
IL-7 signaling must be intermittent, not continuous, during CD8+ T cell homeostasis to promote cell survival instead of cell death
2012
·
Motoko Y Kimura
, Leonid A Pobezinsky
, et al.
·
Nature Immunology
·
143
Administration of recombinant interleukin 12 prevents outgrowth of tumor cells metastasizing spontaneously to lung and lymph nodes.
1995
·
J Mu
, J P Zou
, et al.
·
PubMed
·
133
Lck Availability during Thymic Selection Determines the Recognition Specificity of the T Cell Repertoire
2013
·
François Van Laethem
, Anastasia N. Tikhonova
, et al.
·
Cell
·
112
PDF
Conditional deletion of cytokine receptor chains reveals that IL-7 and IL-15 specify CD8 cytotoxic lineage fate in the thymus
2012
·
Tom M. McCaughtry
, Ruth Etzensperger
, et al.
·
The Journal of Experimental Medicine
·
92
Induction of autoimmune disease in CTLA-4 −/− mice depends on a specific CD28 motif that is required for in vivo costimulation
2007
·
Xuguang Tai
, Francois Van Laethem
, et al.
·
Proceedings of the National Academy of Sciences
·
91
Peripheral Expression of Self-MHC-II Influences the Reactivity and Self-Tolerance of Mature CD4+ T Cells
2002
·
Avinash Bhandoola
, Xuguang Tai
, et al.
·
Immunity
·
90
PDF
Molecular mechanisms underlying IFN-γ-mediated tumor growth inhibition induced during tumor growth inhibition induced during tumor immunotherapy with rIL-12
1996
·
Wen-Gong Yu
, Noriniko Yamamoto
, et al.
·
International Immunology
·
88
A role for CD9 molecules in T cell activation.
1996
·
X G Tai
, Y Yashiro
, et al.
·
The Journal of Experimental Medicine
·
85
PDF
IL-12 produced by antigen-presenting cells induces IL-2-independent proliferation of T helper cell clones
1996
·
S Maruo
, K Toyo-oka
, et al.
·
The Journal of Immunology
·
63
Activated T Cells Secrete an Alternatively Spliced Form of Common γ-Chain that Inhibits Cytokine Signaling and Exacerbates Inflammation
2014
·
Changwan Hong
, Megan A. Luckey
, et al.
·
Immunity
·
60
PDF
Expression of an inducible type of nitric oxide (NO) synthase in the thymus and involvement of NO in deletion of TCR-stimulated double-positive thymocytes
1997
·
X G Tai
, K Toyo-oka
, et al.
·
The Journal of Immunology
·
58
A fundamental difference in the capacity to induce proliferation of naive T cells between CD28 and other co-stimulatory molecules
1998
·
Yumi Yashiro
, Xu-Guang Tai
, et al.
·
European Journal of Immunology
·
56
PDF
How autoreactive thymocytes differentiate into regulatory versus effector CD4+ T cells after avoiding clonal deletion
2023
·
Xuguang Tai
, Alyssa Indart
, et al.
·
Nature Immunology
·
54
PDF
Immune quiescence in the oral mucosa is maintained by a uniquely large population of highly activated Foxp3+ regulatory T cells
2018
·
Joo-Young Park
, Hyunsoo Chung
, et al.
·
Mucosal Immunology
·
52
PDF
CD9-mediated costimulation of TCR-triggered naive T cells leads to activation followed by apoptosis
1997
·
X G Tai
, K Toyooka
, et al.
·
The Journal of Immunology
·
51
The General Transcription Factor TAF7 Is Essential for Embryonic Development but Not Essential for the Survival or Differentiation of Mature T Cells
2012
·
Anne Gegonne
, Xuguang Tai
, et al.
·
Molecular and Cellular Biology
·
48
Identification of lineage-specifying cytokines that signal all CD8+-cytotoxic-lineage-fate 'decisions' in the thymus
2017
·
Ruth Etzensperger
, Tejas Kadakia
, et al.
·
Nature Immunology
·
46
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Works count:
60
Citation count:
4,353
H-index:
32
I10-index:
48
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