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Ieva Drulyte

Observed names: Drulyte I, Drulyte, I., Drulyte, Ieva, I. Drulyte
ORCID: 0000-0003-1117-7699
Observed ORCID: 0000-0003-1117-7699
OpenAlex ID: A5022757209
Oral Estrogen Receptor PROTAC Vepdegestrant (ARV-471) Is Highly Efficacious as Monotherapy and in Combination with CDK4/6 or PI3K/mTOR Pathway Inhibitors in Preclinical ER+ Breast Cancer Models
2024 · Sheryl M. Gough, John J. Flanagan, et al. · Clinical Cancer Research · 229
Approaches to altering particle distributions in cryo-electron microscopy sample preparation
2018 · Ieva Drulyte, Rachel M. Johnson, et al. · Acta Crystallographica Section D Structural Biology · 152
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Sialoglycan binding triggers spike opening in a human coronavirus
2023 · Matti F. Pronker, Robert Creutznacher, et al. · Nature · 83
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Evolving cryo-EM structural approaches for GPCR drug discovery
2021 · Xin Zhang, Rachel M. Johnson, et al. · Structure · 81
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The trispecific DARPin ensovibep inhibits diverse SARS-CoV-2 variants
2022 · Sylvia Rothenberger, Daniel L. Hurdiss, et al. · Nature Biotechnology · 77
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An ACE2-blocking antibody confers broad neutralization and protection against Omicron and other SARS-CoV-2 variants of concern
2022 · Wenjuan Du, Daniel L. Hurdiss, et al. · Science Immunology · 57
Structural insights into the cross-neutralization of SARS-CoV and SARS-CoV-2 by the human monoclonal antibody 47D11
2021 · Juliette Fedry, Daniel L. Hurdiss, et al. · Science Advances · 54
Cryo-EM structure of coronavirus-HKU1 haemagglutinin esterase reveals architectural changes arising from prolonged circulation in humans
2020 · Daniel L. Hurdiss, Ieva Drulyte, et al. · Nature Communications · 38
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Highly potent anti-SARS-CoV-2 multivalent DARPin therapeutic candidates
2020 · Marcel Walser, Sylvia Rothenberger, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 31
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Direct cell extraction of membrane proteins for structure–function analysis
2023 · Ieva Drulyte, Aspen Rene Gutgsell, et al. · Scientific Reports · 26
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A broad-spectrum macrocyclic peptide inhibitor of the SARS-CoV-2 spike protein
2023 · Vito Thijssen, Daniel L. Hurdiss, et al. · Proceedings of the National Academy of Sciences · 23
Computational design of therapeutic antibodies with improved developability: efficient traversal of binder landscapes and rescue of escape mutations
2025 · Frédéric A. Dreyer, Constantin Schneider, et al. · mAbs · 21
Tomo Live : an on-the-fly reconstruction pipeline to judge data quality for cryo-electron tomography workflows
2024 · Maxime Comet, Patricia M. Dijkman, et al. · Acta Crystallographica Section D Structural Biology · 21
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Neutralizing antibodies reveal cryptic vulnerabilities and interdomain crosstalk in the porcine deltacoronavirus spike protein
2024 · Wenjuan Du, Oliver Debski-Antoniak, et al. · Nature Communications · 20
Structural basis for the inhibition of βFXIIa by garadacimab
2024 · Ieva Drulyte, Rajesh Ghai, et al. · Structure · 17
Crystal structure of the putative cyclase IdmH from the indanomycin nonribosomal peptide synthase/polyketide synthase
2019 · Ieva Drulyte, Jana Obajdin, et al. · IUCrJ · 14
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A bivalent spike-targeting nanobody with anti-sarbecovirus activity
2025 · Iris C. Swart, Oliver J. Debski-Antoniak, et al. · Journal of Nanobiotechnology · 5
Integrative structure of norovirus NS3 suggests a role in RNA transport
2026 · Meryl Haas, Tino Hoeksma, et al. · Nature Communications · 4
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Cryo-Electron Microscopy-Based Epitope Mapping
2025 · Ieva Drulyte, Daniel L. Hurdiss · Methods in molecular biology · 4
Thermo Scientific™ Glacios Cryo-TEM: A Versatile 200 kV Tool for Structure-Based Drug Discovery
2021 · Ieva Drulyte, Xin Zhang, et al. · Microscopy and Microanalysis · 2
Data from Oral Estrogen Receptor PROTAC Vepdegestrant (ARV-471) Is Highly Efficacious as Monotherapy and in Combination with CDK4/6 or PI3K/mTOR Pathway Inhibitors in Preclinical ER+ Breast Cancer Models
2024 · Sheryl M. Gough, John J. Flanagan, et al. · 1
PF 06882961 bound to the glucagon-like peptide-1 receptor (GLP-1R)
2021 · M.J. Belousoff, R.M. Johnson, et al. · Worldwide Protein Data Bank · 1
Spike and host glycan determinants of HKU1 airway tropism
2026 · Robert Creutznacher, Louisa E. Wallace, et al. · bioRxiv (Cold Spring Harbor Laboratory)
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Discovery of membrane channel modulators via DNA encoded library screening using native like membrane protein nanoparticles
2026 · Francesco V. Reddavide, Trine L. Toft-Bertelsen, et al. · Scientific Reports
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The gH/gL/gO Complex of Elephant Endotheliotropic Herpesvirus 1A Functions as a Receptor-Binding Complex
2025 · Oliver Debski-Antoniak, Lukas Ermers, et al. · bioRxiv (Cold Spring Harbor Laboratory)
Works count: 43
Citation count: 961
H-index: 15
I10-index: 16
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