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Lukas Dillinger
Observed names:
L Dillinger,
L. Dillinger
Observed institution:
X4 Pharmaceuticals, Inc. (United States)
OpenAlex ID:
A5022827775
Dysregulated stem cell niches and altered lymphocyte recirculation cause B and T cell lymphopenia in WHIM syndrome
2022
·
Sandra Zehentmeier
, Vivian Y. Lim
, et al.
·
Science Immunology
·
25
In vitro potency and pharmacokinetics of APG777, a novel anti–IL-13 mAb
2025
·
Eric Zhu
, Holly Prentice
, et al.
·
Journal of Allergy and Clinical Immunology Global
·
3
Apg777, Anti-il-13 Monoclonal Antibody, Demonstrates Extended Half-life and Sustained Inhibition of Type 2 Inflammatory Biomarkers
2024
·
X. Lim
, E. Winter
, et al.
·
Annals of Allergy Asthma & Immunology
·
3
Prophylactic Administration of the Monoclonal Antibody Adintrevimab Protects against SARS-CoV-2 in Hamster and Non-Human Primate Models of COVID-19
2022
·
Elizabeth E. Zumbrun
, Chengzi I. Kaku
, et al.
·
Antimicrobial Agents and Chemotherapy
·
2
The Combination of APG777 (anti-IL-13) and APG333 (anti-TSLP) Inhibits Central and Local Drivers of Obstructive Airway Disease
2025
·
K. Barth
, G. Wickman
, et al.
·
American Journal of Respiratory and Critical Care Medicine
·
1
Preclinical Potency, Affinity, and Pharmacokinetics of APG990, a Half-Life Extended Antibody Against OX40L
2025
·
Grant Wickman
, Byong Ha Kang
, et al.
·
SKIN The Journal of Cutaneous Medicine
·
1
Zumilokibart (APG777), a half-life extended monoclonal antibody, improves IL-13–driven airway pathology in preclinical asthma models
2026
·
Kristie Barth
, Kimberly Barker
, et al.
·
European Respiratory Journal
0517 Zumilokibart (APG777), a half-life-extended monoclonal antibody, provides rapid and sustained inhibition of type 2 biomarkers in moderate-to-severe atopic dermatitis
2026
·
E. Guttman-Yassky
, M. Gooderham
, et al.
·
Journal of Investigative Dermatology
0553 Zumilokibart (APG777) induces rapid and robust normalization of the lesional and non-lesional atopic dermatitis skin phenotype
2026
·
J. Fiedler
, J. Zhou
, et al.
·
Journal of Investigative Dermatology
PDF
CXCR4 antagonism restores dendritic cell migration and activation in a WHIM syndrome mouse model
2026
·
Alexie Ouchakoff
, Mathilde Puel
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
220 A Combination of APG777 (anti-IL-13) and APG990 (anti-OX40L) Improves Inflammatory and Barrier Disruption Pathologies of Atopic Dermatitis
2025
·
Brittany Mihelich
, Kristie Barth
, et al.
·
Journal of Investigative Dermatology
PDF
264 APG777, a half-life-extended mAb targeting IL-13, demonstrates rapid and sustained inhibition of serum TARC levels in patients with moderate to severe atopic dermatitis
2025
·
Emma Guttman-Yassky
, Sai Thankamony
, et al.
·
Journal of Investigative Dermatology
PDF
62478 The Combination of APG777 (Anti-IL-13) and APG990 (Anti-OX40L) Provides Broad Suppression of Inflammatory Cytokines
2025
·
Grant Wickman
, Kristie Barth
, et al.
·
Journal of the American Academy of Dermatology
The Combination of APG777 (anti-IL-13) and APG333 (anti-TSLP) Improves Type 2 Inflammatory Suppression Compared to Single Agents
2025
·
Kristie Barth
, Grant Wickman
, et al.
·
Journal of Allergy and Clinical Immunology
Preclinical and Pharmacokinetic Characterization of APG333: A Fully Human Monoclonal Antibody that Binds TSLP with High Affinity and Potently Inhibits Downstream Signaling
2025
·
Jessica Meinke
, Jacob Milligan
, et al.
·
Journal of Allergy and Clinical Immunology
PDF
711 - Prolonged half-life and sustained inhibition of key inflammatory biomarkers: a phase 1 study of APG777, a high-affinity humanized IgG1 monoclonal antibody targeting IL-13
2024
·
Xiu Qin Lim
, Erica Winter
, et al.
·
British Journal of Dermatology
758 APG777, a high-affinity humanized IgG1 monoclonal antibody targeting IL-13, demonstrates prolonged half-life and pSTAT6 inhibition in non-human primates
2024
·
E. Zhu
, J. Oh
, et al.
·
Journal of Investigative Dermatology
LB945 Prolonged half-life and sustained inhibition of key inflammatory biomarkers: a phase 1 study of APG777, a high-affinity humanized IgG1 monoclonal antibody targeting IL-13
2024
·
X.Q. Lim
, E. Winter
, et al.
·
Journal of Investigative Dermatology
PDF
APG808, A Fully Human Monoclonal IgG1 Antibody, Binds to IL-4Rα With High Affinity and Blocks IL-13 and IL-4 Mediated Signalling in Multiple In Vitro Assays
2024
·
L. Dillinger
, R. Dabora
, et al.
·
American Journal of Respiratory and Critical Care Medicine
APG808, A High-Affinity Fully Human IgG1 Monoclonal Antibody Targeting IL-4Rα, Demonstrates Prolonged Half-Life in Non-Human Primates
2024
·
L. Dillinger
, R. Dabora
, et al.
·
American Journal of Respiratory and Critical Care Medicine
Abstract 6093: Mavorixafor enhances efficacy of Bruton tyrosine kinase inhibitors by overcoming the protective effect of bone marrow stroma on tumor cells in Waldenström’s macroglobulinemia
2022
·
Chi Nguyen
, Halenya Monticelli
, et al.
·
Cancer Research
AB1108 Handling of de novo arthritis in adults by general practitioners: a survey in a french cohort
2017
·
S Lecauchois
, S Gentile
, et al.
·
Annals of the Rheumatic Diseases
PDF
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Works count:
22
Citation count:
35
H-index:
3
I10-index:
1
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