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Madeline N. Hayes

Observed names: Hayes, Madeline, Hayes, Madeline N., M.N. Hayes, Madeline Hayes, Madeline N Hayes
Observed institutions: Harvard University, Oregon Health & Science University, University of Toronto, Great Ormond Street Hospital, Hospital for Sick Children, Massachusetts General Hospital, Harvard Stem Cell Institute, OHSU Knight Cancer Institute
ORCID: 0000-0002-0089-8995
Observed ORCID: 0000-0002-0089-8995
OpenAlex ID: A5022828739
Visualizing Engrafted Human Cancer and Therapy Responses in Immunodeficient Zebrafish
2019 · Chuan Yan, Dalton C. Brunson, et al. · Cell · 246
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ptk7 mutant zebrafish models of congenital and idiopathic scoliosis implicate dysregulated Wnt signalling in disease
2014 · Madeline Hayes, Xiaochong Gao, et al. · Nature Communications · 172
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Wnt5a secretion stimulated by the extracellular calcium-sensing receptor inhibits defective Wnt signaling in colon cancer cells
2007 · R. John MacLeod, Madeline Hayes, et al. · American Journal of Physiology-Gastrointestinal and Liver Physiology · 148
Ptk7 promotes non-canonical Wnt/PCP-mediated morphogenesis and inhibits Wnt/β-catenin-dependent cell fate decisions during vertebrate development
2013 · Madeline Hayes, Mizue Naito, et al. · Development · 113
Nedd4‐1 binds and ubiquitylates activated FGFR1 to control its endocytosis and function
2011 · Avinash Persaud, Philipp Alberts, et al. · The EMBO Journal · 94
Imaging tumour cell heterogeneity following cell transplantation into optically clear immune-deficient zebrafish
2016 · Qin Tang, John C. Moore, et al. · Nature Communications · 87
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Insights into pediatric rhabdomyosarcoma research: Challenges and goals
2019 · Marielle E. Yohe, Christine M. Heske, et al. · Pediatric Blood & Cancer · 78
Vangl2/RhoA Signaling Pathway Regulates Stem Cell Self-Renewal Programs and Growth in Rhabdomyosarcoma
2018 · Madeline N. Hayes, Karin McCarthy, et al. · Cell stem cell · 75
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tp53 deficiency causes a wide tumor spectrum and increases embryonal rhabdomyosarcoma metastasis in zebrafish
2018 · Myron S Ignatius, Madeline N Hayes, et al. · eLife · 74
Myogenic regulatory transcription factors regulate growth in rhabdomyosarcoma
2017 · Inês M Tenente, Madeline N Hayes, et al. · eLife · 73
Single-cell analysis and functional characterization uncover the stem cell hierarchies and developmental origins of rhabdomyosarcoma
2022 · Yun Wei, Qian Qin, et al. · Nature Cancer · 67
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The NOTCH1/SNAIL1/MEF2C Pathway Regulates Growth and Self-Renewal in Embryonal Rhabdomyosarcoma
2017 · Myron S. Ignatius, Madeline N. Hayes, et al. · Cell Reports · 63
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Depletion of plasma membrane PtdIns(4,5)P2 reveals essential roles for phosphoinositides in flagellar biogenesis
2008 · Ho-Chun Wei, Janet Rollins, et al. · Journal of Cell Science · 51
Discovering novel oncogenic pathways and new therapies using zebrafish models of sarcoma
2017 · M.N. Hayes, D.M. Langenau · Methods in cell biology · 16
A syngeneic spontaneous zebrafish model of tp53-deficient, EGFRvIII, and PI3KCAH1047R-driven glioblastoma reveals inhibitory roles for inflammation during tumor initiation and relapse in vivo
2024 · Alex Weiss, Cassandra D'Amata, et al. · eLife · 12
SHP2 Inhibition with TNO155 Increases Efficacy and Overcomes Resistance of ALK Inhibitors in Neuroblastoma
2023 · Ivette Valencia-Sama, Lynn Kee, et al. · Cancer Research Communications · 10
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Defining function of wild-type and three patient-specific TP53 mutations in a zebrafish model of embryonal rhabdomyosarcoma
2023 · Jiangfei Chen, Kunal Baxi, et al. · eLife · 9
Modeling human brain tumors in flies, worms, and zebrafish: From proof of principle to novel therapeutic targets
2020 · Uswa Shahzad, Michael S Taccone, et al. · Neuro-Oncology · 9
In Vivo Imaging of Cancer in Zebrafish
2016 · Myron S. Ignatius, Madeline Hayes, et al. · Advances in experimental medicine and biology · 9
Fluid shear stress activates a targetable mechano-metastatic cascade to promote medulloblastoma metastasis
2025 · Hyun-Kee Min, Hongyu Zhao, et al. · Nature Biomedical Engineering · 8
DNA damage response deficiency enhances neuroblastoma progression and sensitivity to combination PARP and ATR inhibition
2025 · Madeline N. Hayes, Sarah Cohen-Gogo, et al. · Cell Reports · 8
Author response: tp53 deficiency causes a wide tumor spectrum and increases embryonal rhabdomyosarcoma metastasis in zebrafish
2018 · Myron S Ignatius, Madeline N Hayes, et al. · 1
Ptk7 promotes non-canonical Wnt/PCP-mediated morphogenesis and inhibits Wnt/β-catenin-dependent cell fate decisions during vertebrate development
2013 · Madeline Hayes, Mizue Naito, et al. · Development · 1
Abstract PR004: Characterization of patient-specific CHEK2 genetic variants in high-risk neuroblastoma
2026 · Xueting (Ting) Xiong, Meagan Beffort, et al. · Cancer Research
Efficacy of RMC-6236 (Daraxonrasib) and novel combination strategies targeting resistance in RAS pathway-driven neuroblastoma
2026 · Ivette Valencia-Sama, Lynn Kee, et al. · bioRxiv (Cold Spring Harbor Laboratory)
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Works count: 95
Citation count: 1,424
H-index: 14
I10-index: 16
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