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Eric Tu
Institution:
AstraZeneca (United States)
Observed institutions:
AstraZeneca (United Kingdom),
National Institutes of Health,
The University of Melbourne,
National Institute of Dental and Craniofacial Research,
AstraZeneca (United States)
ORCID:
0009-0007-6174-8556
Observed ORCID:
0009-0007-6174-8556
OpenAlex ID:
A5022849360
Regulatory T cells in cardiovascular diseases
2015
·
Xiao Meng
, Jianmin Yang
, et al.
·
Nature Reviews Cardiology
·
404
High Glucose Intake Exacerbates Autoimmunity through Reactive-Oxygen-Species-Mediated TGF-β Cytokine Activation
2019
·
Dunfang Zhang
, Wenwen Jin
, et al.
·
Immunity
·
275
PDF
The mucosal immune system in the oral cavity—an orchestra of T cell diversity
2014
·
Rui-Qing Wu
, Dun-Fang Zhang
, et al.
·
International Journal of Oral Science
·
171
PDF
Anti–PD-L1 and anti-CD73 combination therapy promotes T cell response to EGFR-mutated NSCLC
2022
·
Eric Tu
, Kelly McGlinchey
, et al.
·
JCI Insight
·
117
PDF
T Cell Receptor-Regulated TGF-β Type I Receptor Expression Determines T Cell Quiescence and Activation
2018
·
Eric Tu
, Cheryl P.Z. Chia
, et al.
·
Immunity
·
100
The DNA-binding inhibitor Id3 regulates IL-9 production in CD4+ T cells
2015
·
Hiroko Nakatsukasa
, Dunfang Zhang
, et al.
·
Nature Immunology
·
80
TGFβ in T cell biology and tumor immunity: Angel or devil?
2014
·
Eric Tu
, Pei Zhi Cheryl Chia
, et al.
·
Cytokine & Growth Factor Reviews
·
61
Antitumor activity of AZD0754, a dnTGFβRII-armored, STEAP2-targeted CAR-T cell therapy, in prostate cancer
2023
·
Peter Zanvit
, Dewald van Dyk
, et al.
·
Journal of Clinical Investigation
·
59
PDF
Phase I study of C-CAR031, a GPC3-specific TGFβRIIDN armored autologous CAR-T, in patients with advanced hepatocellular carcinoma (HCC).
2024
·
Qi Zhang
, Qihan Fu
, et al.
·
Journal of Clinical Oncology
·
56
Extracellular Vesicles from Apoptotic Cells Promote TGFβ Production in Macrophages and Suppress Experimental Colitis
2019
·
Hua Chen
, Shimpei Kasagi
, et al.
·
Scientific Reports
·
55
PDF
Manipulating Regulatory T Cells: A Promising Strategy to Treat Autoimmunity
2015
·
Dunfang Zhang
, Eric Tu
, et al.
·
Immunotherapy
·
40
PARP-1 regulates expression of TGF-β receptors in T cells
2013
·
Pin Zhang
, Hiroko Nakatsukasa
, et al.
·
Blood
·
39
Phase I study of a recombinant attenuated oncolytic virus, MEDI5395 (NDV–GM-CSF), administered systemically in combination with durvalumab in patients with advanced solid tumors
2024
·
Diwakar Davar
, Benedito A Carneiro
, et al.
·
Journal for ImmunoTherapy of Cancer
·
30
PDF
Autoimmune Gastritis and Pernicious Anemia
2013
·
Ian R. van Driel
, Eric Tu
, et al.
·
Elsevier eBooks
·
28
Both IFN ‐γ and IL ‐17 are required for the development of severe autoimmune gastritis
2012
·
Eric Tu
, Desmond K.Y. Ang
, et al.
·
European Journal of Immunology
·
27
Pathogenic T cells persist after reversal of autoimmune disease by immunosuppression with regulatory T cells
2013
·
Eric Tu
, Dorothée Bourges
, et al.
·
European Journal of Immunology
·
14
PDF
A Convenient Model of Severe, High Incidence Autoimmune Gastritis Caused by Polyclonal Effector T Cells and without Perturbation of Regulatory T Cells
2011
·
Eric Tu
, Desmond K. Y. Ang
, et al.
·
PLoS ONE
·
5
PDF
IPH5201, an Anti-CD39 mAb, as Monotherapy or in Combination with Durvalumab in Advanced Solid Tumors
2025
·
John Powderly
, Martina Imbimbo
, et al.
·
Cancer Research Communications
·
4
PDF
GPC3-specific dnTGFβRII-armoured CAR T cells for hepatocellular carcinoma
2026
·
Qi Zhang
, Qihan Fu
, et al.
·
Nature
·
3
IL-12 encoding oNDV synergizes with CAR-T cells in orthotopic models of non-small cell lung cancer
2024
·
Amanda Rosewell Shaw
, Daisuke Morita
, et al.
·
Molecular Therapy Oncology
·
3
Abstract LB085: Antitumor activity of AZD0754, a dnTGFbRII armored STEAP2 targeted CAR-T therapy, in preclinical models of prostate cancer
2023
·
Dewald van Dyk
, Peter Zanvit
, et al.
·
Cancer Research
·
2
Abstract 2837: Synthetic TGFb blockade preserves effector function and maintains stemness of GPC3 CAR-T against hepatocellular carcinoma
2022
·
Nina J. Chu
, Michael G. Overstreet
, et al.
·
Cancer Research
·
2
Abstract 3793: Advancing GPC3-positive solid tumor therapy with AZD9793, a novel CD8-guided T cell engager with potent pre-clinical efficacy and superior therapeutic index over GPC3 x CD3 formats
2025
·
Cristina Bergamaschi
, Cerys Lovatt
, et al.
·
Cancer Research
·
1
1058 Development of AZD9793 for GPC3+ solid tumor treatment: a next generation CD8-guided T cell engager with superior therapeutic index versus conventional formats
2024
·
Cristina Bergamaschi
, Upneet K Sokhi
, et al.
·
Regular and Young Investigator Award Abstracts
·
1
339 Quantitative assessment of CAR-T cell therapy targets using computational pathology
2022
·
Nathalie Harder
, Markus Schick
, et al.
·
Regular and Young Investigator Award Abstracts
·
1
PDF
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Works count:
48
Citation count:
1,579
H-index:
15
I10-index:
16
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