Author

Federica Orvieto

Observed name: F. Orvieto

Observed institutions: University of Siena, Merck & Co., Inc., Rahway, NJ, USA (United States), IRBM

OpenAlex ID: A5023173760

Discovery of Raltegravir, a Potent, Selective Orally Bioavailable HIV-Integrase Inhibitor for the Treatment of HIV-AIDS Infection

2008 · Vincenzo Summa, Alessia Petrocchi, et al. · Journal of Medicinal Chemistry · 653

Omomyc Reveals New Mechanisms To Inhibit the MYC Oncogene

2019 · Mark J. Demma, Claudio Mapelli, et al. · Molecular and Cellular Biology · 93

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Tetrazole thioacetanilides: Potent non-nucleoside inhibitors of WT HIV reverse transcriptase and its K103N mutant

2006 · Ester Muraglia, Olaf D. Kinzel, et al. · Bioorganic & Medicinal Chemistry Letters · 90

Dihydroxypyrimidine-4-carboxamides as Novel Potent and Selective HIV Integrase Inhibitors

2007 · Paola Pace, M. Emilia Di Francesco, et al. · Journal of Medicinal Chemistry · 80

Discovery and Synthesis of HIV Integrase Inhibitors: Development of Potent and Orally Bioavailable N-Methyl Pyrimidones

2007 · Cristina Gardelli, Emanuela Nizi, et al. · Journal of Medicinal Chemistry · 67

Identification of substituted pyrazolo[1,5-a]quinazolin-5(4H)-one as potent poly(ADP-ribose)polymerase-1 (PARP-1) inhibitors

2009 · Federica Orvieto, Danila Branca, et al. · Bioorganic & Medicinal Chemistry Letters · 56

Design and Synthesis of Bicyclic Pyrimidinones as Potent and Orally Bioavailable HIV-1 Integrase Inhibitors

2008 · Ester Muraglia, Olaf Kinzel, et al. · Journal of Medicinal Chemistry · 53

A spectroscopic and molecular dynamics study on the aggregation process of a long-acting lipidated therapeutic peptide: the case of semaglutide

2020 · M. Venanzi, M. Savioli, et al. · Soft Matter · 40

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Novel, potent phenethylamide inhibitors of the hepatitis C virus (HCV) NS3 protease: probing the role of P2 aryloxyprolines with hybrid structures

2003 · Federica Orvieto, Uwe Koch, et al. · Bioorganic & Medicinal Chemistry Letters · 30

Oligomerization, albumin binding and catabolism of therapeutic peptides in the subcutaneous compartment: An investigation on lipidated GLP-1 analogs

2022 · Mariana Gallo, Domitilla Vanni, et al. · Journal of Pharmaceutical and Biomedical Analysis · 26

Multiple Synthetic Routes to the Mini-Protein Omomyc and Coiled-Coil Domain Truncations

2019 · Zachary Z. Brown, Claudio Mapelli, et al. · The Journal of Organic Chemistry · 23

Identification and SAR of novel pyrrolo[1,2-a]pyrazin-1(2H)-one derivatives as inhibitors of poly(ADP-ribose) polymerase-1 (PARP-1)

2009 · Giovanna Pescatore, Danila Branca, et al. · Bioorganic & Medicinal Chemistry Letters · 21

Identification of aminoethyl pyrrolo dihydroisoquinolinones as novel poly(ADP-ribose) polymerase-1 inhibitors

2009 · Danila Branca, Mauro Cerretani, et al. · Bioorganic & Medicinal Chemistry Letters · 19

Polypharmacy through Phage Display: Selection of Glucagon and GLP-1 Receptor Co-agonists from a Phage-Displayed Peptide Library

2018 · Anna Demartis, Armin Lahm, et al. · Scientific Reports · 13

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Discovery of MK-1462: GLP-1 and Glucagon Receptor Dual Agonist for the Treatment of Obesity and Diabetes

2022 · Anandan Palani, Andrea R. Nawrocki, et al. · ACS Medicinal Chemistry Letters · 11

The synthesis of tetrahydropyridopyrimidones as a new scaffold for HIV-1 integrase inhibitors

2007 · Olaf D. Kinzel, Edith Monteagudo, et al. · Tetrahedron Letters · 11

An Expedient Synthesis of 14,14-Dimethyl-3,7-diazatricyclo[8.3.11,10.03.8]tetradec-7-en-4-one-12α-yl Cinnamate, an Unusual Heterocyclic Compound Resembling the A/B/C Core of Taxanes

1999 · Federica Orvieto, Maurizio Botta, et al. · Synthetic Communications · 4

Discovery of Insulin/GLP-1/Glucagon Triagonists for the Treatment of Diabetes and Obesity

2022 · Chunhui Huang, Anandan Palani, et al. · ACS Medicinal Chemistry Letters · 3

Cyclic Peptide Inhibitors of the MLH1-MSH3 Interaction as a Potential Therapeutic Strategy for Huntington's Disease

2026 · Tasir S Haque, Federica Orvieto, et al. · ChemRxiv · 1

Novel, Potent Phenethylamide Inhibitors of the Hepatitis C Virus (HCV) NS3 Protease: Probing the Role of P2 Aryloxyprolines with Hybrid Structures.

2003 · Federica Orvieto, Uwe Koch, et al. · ChemInform · 1

Cyclic Peptide Inhibitors of the MLH1-MSH3 Interaction as a Potential Therapeutic Strategy for Huntington's Disease

2026 · Tasir S Haque, Federica Orvieto, et al. · ChemRxiv

ChemInform Abstract: An Expedient Synthesis of 14,14‐Dimethyl‐3,7‐diazatricyclo [8.3.11,10.03,8]tetradec‐7‐en‐4‐one‐12α‐yl Cinnamate, an Unusual Heterocyclic Compound Resembling the A/B/C Core of Taxanes.

1999 · Federica Orvieto, Maurizio Botta, et al. · ChemInform

Works count: 22

Citation count: 1,295

H-index: 13

I10-index: 16