Product
Help
Pricing
About
Jobs
Log in
Get started
Author
Add to collection
Nichole K. Escalante
Observed names:
N K Escalante,
N.K. Escalante,
Nichole E. Escalante,
Nichole Escalante,
Nichole K Escalante
Institution:
Zymeworks (Canada)
Observed institutions:
Simon Fraser University,
University of Toronto,
Zymeworks (Canada),
Stanford Blood Center,
Stanford Medicine,
Stanford University
show all 6
ORCID:
0000-0003-4037-1634
Observed ORCID:
0000-0003-4037-1634
OpenAlex ID:
A5023182167
Works
28
Awards
3
Lymph node colonization induces tumor-immune tolerance to promote distant metastasis
2022
·
Nathan E. Reticker-Flynn
, Weiruo Zhang
, et al.
·
Cell
·
411
Structure of the IFNγ receptor complex guides design of biased agonists
2019
·
Juan L. Mendoza
, Nichole K. Escalante
, et al.
·
Nature
·
150
The heme-regulated inhibitor is a cytosolic sensor of protein misfolding that controls innate immune signaling
2019
·
Mena Abdel-Nour
, Leticia A. M. Carneiro
, et al.
·
Science
·
127
NKT Cell–Deficient Mice Harbor an Altered Microbiota That Fuels Intestinal Inflammation during Chemically Induced Colitis
2016
·
Thirumahal Selvanantham
, Qiaochu Lin
, et al.
·
The Journal of Immunology
·
122
Circulating NOD1 Activators and Hematopoietic NOD1 Contribute to Metabolic Inflammation and Insulin Resistance
2017
·
Kenny L. Chan
, Theresa H. Tam
, et al.
·
Cell Reports
·
94
PDF
The common mouse protozoaTritrichomonas murisalters mucosal T cell homeostasis and colitis susceptibility
2016
·
Nichole K. Escalante
, Paul Lemire
, et al.
·
The Journal of Experimental Medicine
·
93
PDF
CD3bright signals on γδ T cells identify IL‐17A‐producing Vγ6Vδ1+ T cells
2014
·
C Paget
, M T Chow
, et al.
·
Immunology and Cell Biology
·
83
PDF
CD155 on Human Vascular Endothelial Cells Attenuates the Acquisition of Effector Functions in CD8 T Cells
2011
·
Nichole K. Escalante
, Anna von Rossum
, et al.
·
Arteriosclerosis Thrombosis and Vascular Biology
·
44
Nod1 and Nod2 Enhance TLR-Mediated Invariant NKT Cell Activation during Bacterial Infection
2013
·
Thirumahal Selvanantham
, Nichole K Escalante
, et al.
·
The Journal of Immunology
·
40
Discrete TCR Binding Kinetics Control Invariant NKT Cell Selection and Central Priming
2016
·
Mayra Cruz Tleugabulova
, Nichole K Escalante
, et al.
·
The Journal of Immunology
·
36
Inflammatory Cytokines Determine the Susceptibility of Human CD8 T Cells to Fas-mediated Activation-induced Cell Death through Modulation of FasL and c-FLIPS Expression
2011
·
Anna von Rossum
, Randall Krall
, et al.
·
Journal of Biological Chemistry
·
25
PDF
Abstract 2633: Zanidatamab zovodotin (ZW49) induces hallmarks of immunogenic cell death and is active in patient-derived xenograft models of gastric cancer
2023
·
Stuart D. Barnscher
, Andrea Hernández Rojas
, et al.
·
Cancer Research
·
14
Abstract 6719: TriTCE Co-Stim: A next generation trispecific T cell engager platform with integrated CD28 costimulation, engineered to improve responses in the treatment of solid tumors
2024
·
Lisa Newhook
, Purva Bhojane
, et al.
·
Cancer Research
·
3
Abstract 5121: TriTCE Co-stim, next generation costimulatory trispecific T cell engagers for the treatment of solid tumors
2023
·
Lisa Newhook
, Purva P. Bhojane
, et al.
·
Cancer Research
·
3
Abstract 6716: DLL3 TriTCE Co-Stim: A next generation trispecific T cell engager with integrated CD28 costimulation for the treatment of DLL3-expressing cancers
2024
·
Peter Repenning
, Desmond Lau
, et al.
·
Cancer Research
·
2
Abstract 2935: ZW270, a conditionally masked IL-12 cytokine fusion protein displaying potent anti-tumor activity absent systemic toxicity
2023
·
Maya C. Poffenberger
, Jennifer L. Bishop
, et al.
·
Cancer Research
·
2
Abstract 2926: PROTECTTM, a novel trispecific antibody masking platform with integrated immune modulation displays unique activity and differentiated modes of action
2023
·
Anna von Rossum
, Genevieve Desjardins
, et al.
·
Cancer Research
·
2
1185 Optimization of purine-based TLR7 agonists as payloads for immune-stimulating antibody conjugates (ISACs)
2022
·
Graham Garnett
, Katina Mak
, et al.
·
Journal for ImmunoTherapy of Cancer
·
2
PDF
Abstract 7318: ZW209, a DLL3 targeted trispecific T cell engager with integrated CD28 co-stimulation, demonstrates safety and potent preclinical efficacy in models of small cell lung cancer
2025
·
Desmond Lau
, Peter Repenning
, et al.
·
Cancer Research
·
1
810 Engineering targeted IL-7 delivery to enhance anti-tumor T cell fitness and persistence
2026
·
Desmond Lau
, Scott Lien
, et al.
·
Journal for ImmunoTherapy of Cancer
PDF
1196 TriTCE Co-stim: a differentiated T cell engager platform with conditional cis CD28 co-stimulation is transferable to diverse targeting strategies
2025
·
Chayne L Piscitelli
, Diego Perez Escanda
, et al.
·
Journal for ImmunoTherapy of Cancer
PDF
853 Design of a next generation tumor targeted masked IL-12Fc for enhanced tolerability and localized anti-tumor activity
2025
·
Nichole Escalante
, Sifa Arrafi
, et al.
·
Journal for ImmunoTherapy of Cancer
PDF
1372 TriTCE Co-Stim: a novel trispecific T cell engager platform, with integrated CD28 costimulation, engineered to widen the therapeutic window for treatment of poorly infiltrated tumors
2023
·
Lisa Newhook
, Purva Bhojane
, et al.
·
Journal for ImmunoTherapy of Cancer
PDF
1396 TriTCE CPI: a novel trispecifc T cell engager platform with integrated PD-1/PD-L1 checkpoint inhibition engineered for the treatment of immunosuppressed tumors
2023
·
Meghan M Verstraete
, Maya Poffenberger
, et al.
·
Journal for ImmunoTherapy of Cancer
PDF
Regulation of Mucosal T cell Activation and Inflammation by NLRC3 and Tritrichomonas muris
2017
·
Nichole K. Escalante
·
TSpace (University of Toronto)
PDF
Show more works
View as search
Works count:
28
Citation count:
1,254
H-index:
12
I10-index:
12
Year
Topic
Type
