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Judith Hauptmann
Observed name:
Hauptmann, Judith
Institution:
Silence Therapeutics (Germany)
Observed institutions:
Silence Therapeutics (Germany),
Jena University Hospital,
University of Regensburg,
Friedrich Schiller University Jena
ORCID:
0000-0001-9098-6763
Observed ORCID:
0000-0001-9098-6763
OpenAlex ID:
A5023200347
Turning catalytically inactive human Argonaute proteins into active slicer enzymes
2013
·
Judith Hauptmann
, Anne Dueck
, et al.
·
Nature Structural & Molecular Biology
·
115
Biochemical isolation of Argonaute protein complexes by Ago-APP
2015
·
Judith Hauptmann
, Daniel Schraivogel
, et al.
·
Proceedings of the National Academy of Sciences
·
91
Phosphorylation of Argonaute proteins affects mRNA binding and is essential for microRNA‐guided gene silencing in vivo
2017
·
Miguel Quévillon Huberdeau
, Daniela M Zeitler
, et al.
·
The EMBO Journal
·
88
The Slicer Activity of ARGONAUTE1 is Required Specifically for the Phasing, Not Production, of Trans-Acting Short Interfering RNAs in Arabidopsis
2016
·
Laura Arribas-Hernández
, Antonin Marchais
, et al.
·
The Plant Cell
·
84
Pre-clinical assessment of SLN360, a novel siRNA targeting LPA, developed to address elevated lipoprotein (a) in cardiovascular disease
2022
·
David A. Rider
, Mona Eisermann
, et al.
·
Atherosclerosis
·
62
Argonaute Family Protein Expression in Normal Tissue and Cancer Entities
2016
·
Daniel Völler
, Lisa Linck
, et al.
·
PLoS ONE
·
48
PDF
The Arabidopsis THO/TREX component TEX1 functionally interacts with MOS11 and modulates mRNA export and alternative splicing events
2016
·
Brian B. Sørensen
, Hans F. Ehrnsberger
, et al.
·
Plant Molecular Biology
·
42
Generation of catalytic human Ago4 identifies structural elements important for RNA cleavage
2014
·
Judith Hauptmann
, Lukas Kater
, et al.
·
RNA
·
33
PDF
Ciliated sensory hair cell formation and function require the F-BAR protein syndapin I and the WH2 domain-based actin nucleator Cobl
2012
·
Susann Schüler
, Judith Hauptmann
, et al.
·
Journal of Cell Science
·
32
Argonaute Regulation: Two Roads to the Same Destination
2013
·
Judith Hauptmann
, Gunter Meister
·
Developmental Cell
·
23
PDF
Preclinical Toxicological Assessment of A Novel siRNA, SLN360, Targeting Elevated Lipoprotein (a) in Cardiovascular Disease
2022
·
David Rider
, Simon Chivers
, et al.
·
Toxicological Sciences
·
14
PDF
The beauty of symmetry: siRNA phosphorodithioate modifications reduce stereocomplexity, ease analysis, and can improve in vivo potency
2024
·
Sophie Schöllkopf
, Stefan Rathjen
, et al.
·
Molecular Therapy — Nucleic Acids
·
8
Engineering miRNA features into siRNAs: Guide-strand bulges are compatible with gene repression
2022
·
Judith Hauptmann
, Vivien Hehne
, et al.
·
Molecular Therapy — Nucleic Acids
·
5
PDF
Peptide-Based Isolation of Argonaute Protein Complexes Using Ago-APP
2017
·
Judith Hauptmann
, Gunter Meister
·
Methods in molecular biology
·
3
Abstract 14720: Pre-clinical Safety Assessment of SLN360, a Novel Short Interfering Ribonucleic Acid Targeting LPA
2020
·
David Rider
, Daniel Swerdlow
, et al.
·
Circulation
·
2
Ciliated sensory hair cell formation and function require the F-BAR protein syndapin I and the WH2 domain-based actin nucleator Cobl
2013
·
Susann Schüler
, Judith Hauptmann
, et al.
·
Journal of Cell Science
·
1
Understanding the biological limits of hybridization-dependent siRNA off-target interactions
2026
·
Luca Penso-Dolfin
, Judith Hauptmann
, et al.
·
Molecular Therapy — Nucleic Acids
Arabidopsis THO/TREX成分TEX1は,機能的にMOS11と相互作用して,mRNA核外輸送および代替スプライシングイベントを調節する
2017
·
Bothner Brian
, F Ehrnsberger Hans
, et al.
·
Plant Molecular Biology
Human Argonaute proteins: Analysis of endonucleolytic activity and endogenous phosphorylation sites
2016
·
Hauptmann, Judith
·
University of Regensburg Publication Server (University of Regensburg)
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Works count:
19
Citation count:
651
H-index:
11
I10-index:
11
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