Author

Vahri Beaumont

Observed names: V Beaumont, V. Beaumont

Observed institutions: University of California, Los Angeles, MRC Laboratory of Molecular Biology, CHDI Foundation, University of Bristol, MSD (UK) Limited (United Kingdom), Medical Research Council, University of California, Berkeley

ORCID: 0000-0002-6488-2175

Observed ORCID: 0000-0002-6488-2175

OpenAlex ID: A5023270752

Characterization of Neurophysiological and Behavioral Changes, MRI Brain Volumetry and 1H MRS in zQ175 Knock-In Mouse Model of Huntington's Disease

2012 · Taneli Heikkinen, Kimmo Lehtimäki, et al. · PLoS ONE · 272

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Unravelling and Exploiting Astrocyte Dysfunction in Huntington’s Disease

2017 · Baljit S. Khakh, Vahri Beaumont, et al. · Trends in Neurosciences · 235

Enhancement of synaptic transmission by cyclic AMP modulation of presynaptic Ih channels

2000 · Vahri Beaumont, Robert S. Zucker · Nature Neuroscience · 226

Behavioral and Neurochemical Alterations in Mice Deficient in Anaplastic Lymphoma Kinase Suggest Therapeutic Potential for Psychiatric Indications

2007 · James G Bilsland, Alan Wheeldon, et al. · Neuropsychopharmacology · 189

HDAC4 Reduction: A Novel Therapeutic Strategy to Target Cytoplasmic Huntingtin and Ameliorate Neurodegeneration

2013 · Michal Mielcarek, Christian Landles, et al. · PLoS Biology · 172

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Design, Synthesis, and Biological Evaluation of Potent and Selective Class IIa Histone Deacetylase (HDAC) Inhibitors as a Potential Therapy for Huntington’s Disease

2013 · Roland W. Bürli, Christopher A. Luckhurst, et al. · Journal of Medicinal Chemistry · 150

Striatal Pre- and Postsynaptic Profile of Adenosine A2A Receptor Antagonists

2011 · Marco Orru, Jana Bakešová, et al. · PLoS ONE · 132

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Phosphodiesterase 10A Inhibition Improves Cortico-Basal Ganglia Function in Huntington’s Disease Models

2016 · Vahri Beaumont, Sheng Zhong, et al. · Neuron · 121

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Phosphorylation and Local Presynaptic Protein Synthesis in Calcium- and Calcineurin-Dependent Induction of Crayfish Long-Term Facilitation

2001 · Vahri Beaumont, Ning Zhong, et al. · Neuron · 94

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Roles for Mitochondrial and Reverse Mode Na+/Ca2+Exchange and the Plasmalemma Ca2+ATPase in Post-Tetanic Potentiation at Crayfish Neuromuscular Junctions

2001 · Ning Zhong, Vahri Beaumont, et al. · Journal of Neuroscience · 84

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Somatostatin Receptor Desensitization in NG108-15 Cells

1998 · Vahri Beaumont, Mark B. Hepworth, et al. · Journal of Biological Chemistry · 78

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Expansion of calcium microdomains regulates fast exocytosis at a ribbon synapse

2005 · Vahri Beaumont, Artur Llobet, et al. · Proceedings of the National Academy of Sciences · 74

Real-Time Measurement of Exocytosis and Endocytosis Using Interference of Light

2003 · Artur Llobet, Vahri Beaumont, et al. · Neuron · 70

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Temporal Synaptic Tagging by Ih Activation and Actin

2002 · Vahri Beaumont, Ning Zhong, et al. · Neuron · 69

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The novel KMO inhibitor CHDI-340246 leads to a restoration of electrophysiological alterations in mouse models of Huntington's disease

2016 · Vahri Beaumont, Ladislav Mrzljak, et al. · Experimental Neurology · 60

Evaluation of 5-(Trifluoromethyl)-1,2,4-oxadiazole-Based Class IIa HDAC Inhibitors for Huntington’s Disease

2021 · Andrew J. Stott, Michel C. Maillard, et al. · ACS Medicinal Chemistry Letters · 48

Development and characterization of a CNS-penetrant benzhydryl hydroxamic acid class IIa histone deacetylase inhibitor

2018 · Christopher A. Luckhurst, Omar Aziz, et al. · Bioorganic & Medicinal Chemistry Letters · 47

Oral Administration of the Pimelic Diphenylamide HDAC Inhibitor HDACi 4b Is Unsuitable for Chronic Inhibition of HDAC Activity in the CNS In Vivo

2012 · Maria Beconi, Omar Aziz, et al. · PLoS ONE · 42

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Evidence for an enhancement of excitatory transmission in adult CNS by Wnt signaling pathway modulation

2007 · Vahri Beaumont, Sally-Anne Thompson, et al. · Molecular and Cellular Neuroscience · 42

Visualizing membrane trafficking using total internal reflection fluorescence microscopy

2003 · V. Beaumont · Biochemical Society Transactions · 36

Developing HDAC4-Selective Protein Degraders To Investigate the Role of HDAC4 in Huntington’s Disease Pathology

2022 · Natsuko Macabuag, William Esmieu, et al. · Journal of Medicinal Chemistry · 33

Efficacy of Selective PDE4D Negative Allosteric Modulators in the Object Retrieval Task in Female Cynomolgus Monkeys (Macaca fascicularis)

2014 · Jane S. Sutcliffe, Vahri Beaumont, et al. · PLoS ONE · 31

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HDAC4 Does Not Act as a Protein Deacetylase in the Postnatal Murine Brain In Vivo

2013 · Michal Mielcarek, Tamara Seredenina, et al. · PLoS ONE · 30

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HDinHD: A Rich Data Portal for Huntington’s Disease Research

2021 · Jeff Aaronson, Vahri Beaumont, et al. · Journal of Huntington s Disease · 27

2018 · Fernando E. Padovan-Neto, Lauren Jurkowski, et al. · Nitric Oxide · 27

Works count: 41

Citation count: 2,495

H-index: 25

I10-index: 31