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De Huang
Institution:
University of Science and Technology of China
Observed institutions:
University of Science and Technology of China,
Duke University,
Chinese Academy of Sciences,
Duke Medical Center
ORCID:
0009-0000-6781-9932
Observed ORCID:
0009-0000-6781-9932
OpenAlex ID:
A5023270772
HIF-1-Mediated Suppression of Acyl-CoA Dehydrogenases and Fatty Acid Oxidation Is Critical for Cancer Progression
2014
·
De Huang
, Tingting Li
, et al.
·
Cell Reports
·
352
Cancer-cell-derived GABA promotes β-catenin-mediated tumour growth and immunosuppression
2022
·
De Huang
, Yan Wang
, et al.
·
Nature Cell Biology
·
319
Lin28/let-7 axis regulates aerobic glycolysis and cancer progression via PDK1
2014
·
Xiaoyu Ma
, Chenchen Li
, et al.
·
Nature Communications
·
180
PDF
Hepatocellular carcinoma redirects to ketolysis for progression under nutrition deprivation stress
2016
·
De Huang
, Tingting Li
, et al.
·
Cell Research
·
171
PDF
Polo-like kinase 1 coordinates biosynthesis during cell cycle progression by directly activating pentose phosphate pathway
2017
·
Xiaoyu Ma
, Lin Wang
, et al.
·
Nature Communications
·
140
PDF
miR‐290/371‐Mbd2‐Myc circuit regulates glycolytic metabolism to promote pluripotency
2015
·
Yang Cao
, Wen‐Ting Guo
, et al.
·
The EMBO Journal
·
95
PDF
GABAergic signaling beyond synapses: an emerging target for cancer therapy
2022
·
De Huang
, Peter B. Alexander
, et al.
·
Trends in Cell Biology
·
76
Hypoxia and cancer cell metabolism
2014
·
De Huang
, Chenchen Li
, et al.
·
Acta Biochimica et Biophysica Sinica
·
71
Menin enhances c-Myc-mediated transcription to promote cancer progression
2017
·
Gongwei Wu
, Mengqiu Yuan
, et al.
·
Nature Communications
·
67
PDF
Myc-mediated SDHA acetylation triggers epigenetic regulation of gene expression and tumorigenesis
2020
·
Shi-Ting Li
, De Huang
, et al.
·
Nature Metabolism
·
64
Switching off IMMP2L signaling drives senescence via simultaneous metabolic alteration and blockage of cell death
2018
·
Lifeng Yuan
, Linhui Zhai
, et al.
·
Cell Research
·
57
PDF
Breaking NGF–TrkA immunosuppression in melanoma sensitizes immunotherapy for durable memory T cell protection
2024
·
Tao Yin
, Guoping Wang
, et al.
·
Nature Immunology
·
55
PDF
Lin28 enhances de novo fatty acid synthesis to promote cancer progression via SREBP‐1
2019
·
Yang Zhang
, Chenchen Li
, et al.
·
EMBO Reports
·
35
PDF
Synthetic lethality between HER2 and transaldolase in intrinsically resistant HER2-positive breast cancers
2018
·
Yi Ding
, Chang Gong
, et al.
·
Nature Communications
·
33
PDF
Branched‐Chain Amino Acid Accumulation Fuels the Senescence‐Associated Secretory Phenotype
2023
·
Yaosi Liang
, Christopher Pan
, et al.
·
Advanced Science
·
32
PDF
Therapy-induced senescent tumor cells in cancer relapse
2023
·
Ke-Xin Song
, Jun-Xian Wang
, et al.
·
Journal of the National Cancer Center
·
28
Aberrant cytoplasmic expression of UHRF1 restrains the MHC-I-mediated anti-tumor immune response
2024
·
Lianmei Tan
, Tao Yin
, et al.
·
Nature Communications
·
19
PDF
Antagonizing the irreversible thrombomodulin-initiated proteolytic signaling alleviates age-related liver fibrosis via senescent cell killing
2023
·
Christopher C. Pan
, Raquel Maeso-Díaz
, et al.
·
Cell Research
·
19
PDF
Parkin coordinates mitochondrial lipid remodeling to execute mitophagy
2022
·
Chao‐Chieh Lin
, Jin Yan
, et al.
·
EMBO Reports
·
19
PDF
Nuclear‐Localized BCKDK Facilitates Homologous Recombination Repair to Support Breast Cancer Progression and Therapy Resistance
2025
·
Haiying Liu
, Jiaqian Feng
, et al.
·
Advanced Science
·
5
Correction: Author Correction: Menin enhances c-Myc-mediated transcription to promote cancer progression
2018
·
Gongwei Wu
, Mengqiu Yuan
, et al.
·
Nature Communications
·
5
PDF
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Works count:
22
Citation count:
1,839
H-index:
19
I10-index:
19
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