Author

Douglas M. Cerasoli

Observed names: Cerasoli, D. M., Cerasoli, Douglas M., D M Cerasoli, D. M. Cerasoli, D.M. Cerasoli, Doug M. Cerasoli, Douglas Cerasoli, Douglas M Cerasoli, Douglas M. Cerasoli

Institution: United States Army

Observed institutions: The Wistar Institute, University of North Carolina at Chapel Hill, University of Maryland, Baltimore, St. Jude Children's Research Hospital, United States Army, Duke Medical Center, University of Delaware

OpenAlex ID: A5023315756

In Situ Studies of the Primary Immune Response to (4-Hydroxy-3-Nitrophenyl)Acetyl. V. Affinity Maturation Develops in Two Stages of Clonal Selection

1998 · Yoshimasa Takahashi, Pinaki R. Dutta, et al. · The Journal of Experimental Medicine · 342

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Recombinant human butyrylcholinesterase from milk of transgenic animals to protect against organophosphate poisoning

2007 · Yue-Jin Huang, Yue Huang, et al. · Proceedings of the National Academy of Sciences · 214

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Stoichiometric and catalytic scavengers as protection against nerve agent toxicity: A mini review

2006 · David E. Lenz, David Yeung, et al. · Toxicology · 203

Protection against soman or VX poisoning by human butyrylcholinesterase in guinea pigs and cynomolgus monkeys

2005 · David E. Lenz, Donald M. Maxwell, et al. · Chemico-Biological Interactions · 118

Stereoselective Hydrolysis of Organophosphate Nerve Agents by the Bacterial Phosphotriesterase

2010 · Ping-Chuan Tsai, Andrew Bigley, et al. · Biochemistry · 116

Relaxed Negative Selection in Germinal Centers and Impaired Affinity Maturation in bcl-xL Transgenic Mice

1999 · Yoshimasa Takahashi, Douglas M. Cerasoli, et al. · The Journal of Experimental Medicine · 110

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(07) In vitro and in vivo characterization of recombinant human butyrylcholinesterase (Protexia™) as a potential nerve agent bioscavenger

2005 · D.M. Cerasoli, E.M. Griffiths, et al. · Chemico-Biological Interactions · 88

Structure/function analyses of human serum paraoxonase (HuPON1) mutants designed from a DFPase-like homology model

2004 · David T. Yeung, Denis Josse, et al. · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · 85

Plant-derived human butyrylcholinesterase, but not an organophosphorous-compound hydrolyzing variant thereof, protects rodents against nerve agents

2010 · Brian C. Geyer, Latha Kannan, et al. · Proceedings of the National Academy of Sciences · 81

Nanoscavenger provides long-term prophylactic protection against nerve agents in rodents

2019 · Peng Zhang, Erik J. Liu, et al. · Science Translational Medicine · 75

Crystal Structures of Human Carboxylesterase 1 in Covalent Complexes with the Chemical Warfare Agents Soman and Tabun,

2007 · Christopher D. Fleming, Carol C. Edwards, et al. · Biochemistry · 72

Effect of antibody binding on protein motions studied by hydrogen-exchange labeling and two-dimensional NMR

1992 · Leland Mayne, Yvonne Paterson, et al. · Biochemistry · 70

Production of ES1 Plasma Carboxylesterase Knockout Mice for Toxicity Studies

2011 · Ellen G. Duysen, Frank Koentgen, et al. · Chemical Research in Toxicology · 66

Analysis of active‐site amino‐acid residues of human serum paraoxonase using competitive substrates

2005 · David T. Yeung, David E. Lenz, et al. · FEBS Journal · 62

Substantially improved pharmacokinetics of recombinant human butyrylcholinesterase by fusion to human serum albumin

2008 · Yue-Jin Huang, Paul M Lundy, et al. · BMC Biotechnology · 60

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Human Carboxylesterase 1 Stereoselectively Binds the Nerve Agent Cyclosarin and Spontaneously Hydrolyzes the Nerve Agent Sarin

2010 · Andrew C. Hemmert, Tamara C. Otto, et al. · Molecular Pharmacology · 56

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Balancing the stability and the catalytic specificities of OP hydrolases with enhanced V-agent activities

2008 · T.E. Reeves, M.E. Wales, et al. · Protein Engineering Design and Selection · 52

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Human paraoxonase double mutants hydrolyze V and G class organophosphorus nerve agents

2012 · Stephen D. Kirby, Joseph R. Norris, et al. · Chemico-Biological Interactions · 50

Dramatic Differences in Organophosphorus Hydrolase Activity between Human and Chimeric Recombinant Mammalian Paraoxonase-1 Enzymes

2009 · Tamara C. Otto, Christina K. Harsch, et al. · Biochemistry · 47

Direct detection of stereospecific soman hydrolysis by wild‐type human serum paraoxonase

2007 · David T. Yeung, J. Richard Smith, et al. · FEBS Journal · 43

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Butyrylcholinesterase as a therapeutic drug for protection against percutaneous VX

2010 · David E. Lenz, Edward D. Clarkson, et al. · Chemico-Biological Interactions · 41

Purification and characterization of functional human paraoxonase-1 expressed in Trichoplusia ni larvae

2010 · Tamara C. Otto, Shane A. Kasten, et al. · Chemico-Biological Interactions · 37

Low avidity recognition of a class II-restricted neo-self peptide by virus-specific T cells

1995 · Douglas M. Cerasoli, James McGrath, et al. · International Immunology · 36

Probing the activity of a non-oxime reactivator for acetylcholinesterase inhibited by organophosphorus nerve agents

2016 · C. Linn Cadieux, Haoyu Wang, et al. · Chemico-Biological Interactions · 35

In silico analyses of substrate interactions with human serum paraoxonase 1

2008 · Xin Hu, Xiaohui Jiang, et al. · Proteins Structure Function and Bioinformatics · 35

Works count: 99

Citation count: 2,910

H-index: 29

I10-index: 56