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Aurore Morello

Observed names: A. Morello, Aurore morello
Observed institutions: Centre National de la Recherche Scientifique, Memorial Sloan Kettering Cancer Center, Université de Bordeaux, OSE Immunotherapeutics (France), Immunology from Concept and Experiments to Translation, Université Bordeaux Segalen
ORCID: 0000-0003-3202-3779
Observed ORCID: 0000-0003-3202-3779
OpenAlex ID: A5023411196
Human CAR T cells with cell-intrinsic PD-1 checkpoint blockade resist tumor-mediated inhibition
2016 · Leonid Cherkassky, Aurore Morello, et al. · Journal of Clinical Investigation · 1,110
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Mesothelin-Targeted CARs: Driving T Cells to Solid Tumors
2015 · Aurore Morello, Michel Sadelain, et al. · Cancer Discovery · 502
CAR T-cell intrinsic PD-1 checkpoint blockade: A two-in-one approach for solid tumor immunotherapy
2016 · Nan Chen, Aurore Morello, et al. · OncoImmunology · 137
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Selective SIRPα blockade reverses tumor T cell exclusion and overcomes cancer immunotherapy resistance
2020 · Vanessa Gauttier, Sabrina Pengam, et al. · Journal of Clinical Investigation · 84
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Imaging CAR T-cell kinetics in solid tumors: Translational implications
2021 · Matthew S. Skovgard, Hocine R. Hocine, et al. · Molecular Therapy — Oncolytics · 52
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Tumor-Targeted Nonablative Radiation Promotes Solid Tumor CAR T-cell Therapy Efficacy
2023 · Hue Tu Quach, Matthew S. Skovgard, et al. · Cancer Immunology Research · 35
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Functional Characterization of a Chimeric Soluble Fas Ligand Polymer with In Vivo Anti-Tumor Activity
2013 · Sophie Daburon, Christel Devaud, et al. · PLoS ONE · 28
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Tissue-resident memory CD8 T-cell responses elicited by a single injection of a multi-target COVID-19 vaccine
2020 · V. Gauttier, A. Morello, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 18
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Abstract 1753: SIRPa inhibition monotherapy leads to dramatic change in solid tumor microenvironment and prevents metastasis development
2018 · Justine Durand, Vanessa Gauttier, et al. · Cancer Research · 5
Abstract 910: A novel bifunctional anti-PD-1 IL-7 fusion protein to reinvigorate exhausted T cell and disarms Treg suppressive activity
2020 · Aurore Morello, Justine Durand, et al. · Cancer Research · 3
Enhancing Production and Cytotoxic Activity of Polymeric Soluble FasL-Based Chimeric Proteins by Concomitant Expression of Soluble FasL
2013 · Aurore Morello, Sophie Daburon, et al. · PLoS ONE · 3
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1370 Anti-PD-1/IL-7v immunocytokine favors proliferation & survival of TCF1+ stem like memory T cells and a durable in vivo efficacy in monotherapy or using combinatorial strategy
2023 · Aurore Morello, Justine Durand, et al. · Journal for ImmunoTherapy of Cancer · 2
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OA14.03 Clinical Rationale and Preclinical Evidence for Chimeric Antigen Receptor (CAR) T Cell Therapy Clinical Trial in KRAS-Mutant Lung Cancer
2019 · J. Minehart, T. Eguchi, et al. · Journal of Thoracic Oncology · 2
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Abstract 1684: Selective SIRPa blockade potentiates dendritic cell antigen cross-presentation and triggers memory T-cell antitumor responses
2018 · Vanessa Gauttier, Sabrina Pengam, et al. · Cancer Research · 2
MA04.11 Mechanistic Insights into CAR T-Cell Efficacy in the Treatment of Heterogenous Antigen Expressing Lung Adenocarcinoma
2017 · Aurore Morello, Masha Zeltsman, et al. · Journal of Thoracic Oncology · 2
A Phase 1 dose-escalation study to evaluate safety, pharmacokinetics, and pharmacodynamics of OSE-279, an anti-PD-1 monoclonal antibody in patients with advanced solid tumours
2026 · Marie Robert, Nuria Kotecki, et al. · European Journal of Cancer · 1
1366 Anti-PD-1/IL-7v bispecific antibody promotes TCF1+ stem like T cells expansion and long-lasting in vivo efficacy
2022 · Aurore Morello, Margaux Seite, et al. · Journal for ImmunoTherapy of Cancer · 1
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826 IL7R TME expression correlates with immunotherapy response and is associated with T-cell stemness with decreased apoptosis
2022 · Nicolas Poirier, Isabelle Girault, et al. · Journal for ImmunoTherapy of Cancer · 1
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794 Long-term anti-tumor preclinical efficacy of an optimized anti PD-1/IL-7 bifunctional antibody sustaining activation of progenitor stem-like CD8 TILs and disarming Treg suppressive activity
2021 · Aurore morello, Margaux Seite, et al. · Journal for ImmunoTherapy of Cancer · 1
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OA02.06 Converting Tumor-Mediated PD-L1 Inhibition into CAR T-Cell Costimulation to Potentiate Thoracic Cancers Immunotherapy
2017 · Aurore Morello, Nan Chen, et al. · Journal of Thoracic Oncology · 1
Mesothelin-targeted T Cells Gene-Engineered with 4-1BB Costimulation Overcome Tumor-Mediated Immunoinhibition and Eradicate Established Solid Tumors
2014 · Leonid Cherkassky, Jonathan Villena-Vargas, et al. · Journal of the American College of Surgeons · 1
CLEC-1 promotes early IFN response in cDC1s and favors immune dysregulation during sepsis in mice
2026 · Thomas Teja Ogor, Esther Porée, et al. · iScience
Novel agonist monoclonal antibody targeting GPCR to decrease neutrophil accumulation and initiate resolution of chronic inflammation 2310040
2026 · Charles-Antoine Coupet, Charlène Trilleaud, et al. · The Journal of Immunology
Emerging GPCR Agonist-Based Therapies to Trigger the Resolution of Inflammation
2026 · Vanessa Gauttier, Charles-Antoine Coupet, et al. · Current topics in microbiology and immunology
Supplementary Table S1 from Tumor-Targeted Nonablative Radiation Promotes Solid Tumor CAR T-cell Therapy Efficacy
2025 · Hue Tu Quach, Matthew S. Skovgard, et al.
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Works count: 50
Citation count: 1,991
H-index: 8
I10-index: 8
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