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Jamie R. Bhagwan

Observed names: Jamie Bhagwan, Jamie R Bhagwan, Jamie Ronald Bhagwan
Institution: Cambridge College
ORCID: 0000-0002-3333-730X
Observed ORCID: 0000-0002-3333-730X
OpenAlex ID: A5023427665
CRISPR/Cas9 editing in human pluripotent stem cell-cardiomyocytes highlights arrhythmias, hypocontractility, and energy depletion as potential therapeutic targets for hypertrophic cardiomyopathy
2018 · Diogo Mosqueira, Ingra Mannhardt, et al. · European Heart Journal · 244
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Isogenic Pairs of hiPSC-CMs with Hypertrophic Cardiomyopathy/LVNC-Associated ACTC1 E99K Mutation Unveil Differential Functional Deficits
2018 · James G.W. Smith, Thomas Owen, et al. · Stem Cell Reports · 75
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Isogenic models of hypertrophic cardiomyopathy unveil differential phenotypes and mechanism-driven therapeutics
2020 · Jamie R. Bhagwan, Diogo Mosqueira, et al. · Journal of Molecular and Cellular Cardiology · 64
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Modeling Hypertrophic Cardiomyopathy: Mechanistic Insights and Pharmacological Intervention
2019 · Diogo Mosqueira, James G.W. Smith, et al. · Trends in Molecular Medicine · 55
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Variable expression and silencing of CRISPR-Cas9 targeted transgenes identifies the AAVS1 locus as not an entirely safe harbour
2019 · Jamie R. Bhagwan, Emma Collins, et al. · F1000Research · 44
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Simplified Footprint-Free Cas9/CRISPR Editing of Cardiac-Associated Genes in Human Pluripotent Stem Cells
2018 · Alexander Kondrashov, Minh Duc Hoang, et al. · Stem Cells and Development · 28
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Chamber-specific contractile responses of atrial and ventricular hiPSC-cardiomyocytes to GPCR and ion channel targeting compounds: A microphysiological system for cardiac drug development
2024 · Bettina Lickiss, Jan Hunker, et al. · Journal of Pharmacological and Toxicological Methods · 11
Human iPSCs: atrial versus ventricular cardiomyocytes and their functional and pharmacological differences
2026 · Steven David Broadbent, Jamie Ronald Bhagwan, et al. · Biochemical Society Transactions · 1
Modeling atrial fibrillation in vitro: A human iPSC-derived disease platform for therapeutic screening
2026 · Bettina Lickiss, Jan Hunker, et al. · Journal of Pharmacological and Toxicological Methods
SmartHeart: An innovative high throughput assay to generate and assess cardiac micro tissues from hiPSCs answering to the current challenges of drug discovery
2025 · Ahmed Khedher, Patricia Davidson, et al. · Journal of Pharmacological and Toxicological Methods
Analyzing atrial human iPSC-cardiomyocyte responses to GPCR and ion channel modulators: Introducing a chamber-specific cell model for preclinical testing
2025 · Bettina Lickiss, Peter Linder, et al. · Journal of Pharmacological and Toxicological Methods
Contractility-based pharmacological characterization of hiPSC-derived atrial and ventricular cardiomyocytes assessed on the FLEXcyte 96
2025 · Bettina Lickiss, Peter Linder, et al. · Journal of Pharmacological and Toxicological Methods
CRISPR-Cas9 gene targeting of human induced pluripotent stem cells to generate a palette of optical reporter cell lines towards investigating hypertrophic cardiomyopathy
2018 · Jamie R. Bhagwan · Nottingham ePrints (University of Nottingham)
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Works count: 13
Citation count: 522
H-index: 7
I10-index: 7
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