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Helena Cirule

Acute anti‐hyperglycaemic effects of an unripe apple preparation containing phlorizin in healthy volunteers: a preliminary study
2014 · Elina Makarova, Paweł Górnaś, et al. · Journal of the Science of Food and Agriculture · 118
Suppression of intestinal microbiota-dependent production of pro-atherogenic trimethylamine N-oxide by shifting L-carnitine microbial degradation
2014 · Janis Kuka, Edgars Liepinsh, et al. · Life Sciences · 97
Comparative pharmacological activity of optical isomers of phenibut
2008 · Maija Dambrova, Liga Zvejniece, et al. · European Journal of Pharmacology · 77
Mildronate decreases carnitine availability and up-regulates glucose uptake and related gene expression in the mouse heart
2008 · Edgars Liepinsh, Reinis Vilskersts, et al. · Life Sciences · 69
The heart is better protected against myocardial infarction in the fed state compared to the fasted state
2013 · Edgars Liepinsh, Marina Makrecka, et al. · Metabolism · 67
Protective effects of mildronate in an experimental model of type 2 diabetes in Goto‐Kakizaki rats
2009 · Edgars Liepinsh, Reinis Vilskersts, et al. · British Journal of Pharmacology · 67
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Long-chain acylcarnitine content determines the pattern of energy metabolism in cardiac mitochondria
2014 · Marina Makrecka, Janis Kuka, et al. · Molecular and Cellular Biochemistry · 61
Activated peroxisomal fatty acid metabolism improves cardiac recovery in ischemia-reperfusion
2013 · Edgars Liepinsh, Elina Skapare, et al. · Naunyn-Schmiedeberg s Archives of Pharmacology · 53
The Cardioprotective Effect of Mildronate is Diminished After Co-Treatment With l -Carnitine
2011 · Janis Kuka, Reinis Vilskersts, et al. · Journal of Cardiovascular Pharmacology and Therapeutics · 53
Microbiota-Derived Metabolite Trimethylamine N-Oxide Protects Mitochondrial Energy Metabolism and Cardiac Functionality in a Rat Model of Right Ventricle Heart Failure
2021 · Melita Videja, Reinis Vilskersts, et al. · Frontiers in Cell and Developmental Biology · 50
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Inhibition of L‐carnitine biosynthesis and transport by methyl‐γ‐butyrobetaine decreases fatty acid oxidation and protects against myocardial infarction
2014 · E Liepinsh, M Makrecka‐Kuka, et al. · British Journal of Pharmacology · 44
Anti-diabetic effects of mildronate alone or in combination with metformin in obese Zucker rats
2011 · Edgars Liepinsh, Elina Skapare, et al. · European Journal of Pharmacology · 32
Effects of Long‐Term Mildronate Treatment on Cardiac and Liver Functions in Rats
2009 · Edgars Liepinsh, Janis Kuka, et al. · Basic & Clinical Pharmacology & Toxicology · 31
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Empagliflozin Protects Cardiac Mitochondrial Fatty Acid Metabolism in a Mouse Model of Diet-Induced Lipid Overload
2020 · Marina Makrecka-Kuka, Stanislava Korzh, et al. · Cardiovascular Drugs and Therapy · 29
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Myocardial Infarct Size-Limiting and Anti-Arrhythmic Effects of Mildronate Orotate in the Rat Heart
2009 · Reinis Vilskersts, Edgars Liepinsh, et al. · Cardiovascular Drugs and Therapy · 28
Effect of inhibiting carnitine biosynthesis on male rat sexual performance
2008 · Maija Dambrova, Helena Cirule, et al. · Physiology & Behavior · 28
Vasodilating and antiarrhythmic activity of heteryl lactones
1999 · Ludmila Leite, Daina Jansone, et al. · European Journal of Medicinal Chemistry · 28
Antibiotic class with potent in vivo activity targeting lipopolysaccharide synthesis in Gram-negative bacteria
2024 · Douglas L. Huseby, Sha Cao, et al. · Proceedings of the National Academy of Sciences · 26
Methyl-γ-butyrobetaine decreases levels of acylcarnitines and attenuates the development of atherosclerosis
2015 · Reinis Vilskersts, Janis Kuka, et al. · Vascular Pharmacology · 24
Selective inhibition of OCTN2 is more effective than inhibition of gamma-butyrobetaine dioxygenase to decrease the availability of l-carnitine and to reduce myocardial infarct size
2014 · Edgars Liepinsh, Marina Makrecka, et al. · Pharmacological Research · 24
Mitochondrial Function in the Kidney and Heart, but Not the Brain, is Mainly Altered in an Experimental Model of Endotoxaemia
2019 · Marina Makrecka-Kuka, Stanislava Korzh, et al. · Shock · 23
Administration of L-carnitine and mildronate improves endothelial function and decreases mortality in hypertensive Dahl rats
2011 · Reinis Vilskersts, Janis Kuka, et al. · Pharmacological Reports · 23
Carnitine and γ‐Butyrobetaine Stimulate Elimination of Meldonium due to Competition for OCTN2‐mediated Transport
2016 · Edgars Liepinsh, Elina Makarova, et al. · Basic & Clinical Pharmacology & Toxicology · 22
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Protective Effects of Meldonium in Experimental Models of Cardiovascular Complications with a Potential Application in COVID-19
2021 · Reinis Vilskersts, Dana Kigitovica, et al. · International Journal of Molecular Sciences · 21
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Loop diuretics decrease the renal elimination rate and increase the plasma levels of trimethylamine‐N‐oxide
2018 · G. Latkovskis, E. Makarova, et al. · British Journal of Clinical Pharmacology · 19
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Works count: 40
Citation count: 1,188
H-index: 22
I10-index: 27
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