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Dale J. Calleja

Observed names: Dale Calleja, Dale J Calleja
ORCID: 0000-0002-8306-0900
Observed ORCID: 0000-0002-8306-0900
OpenAlex ID: A5023712205
TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS
2020 · Chien-Hsiung Yu, Sophia Davidson, et al. · Cell · 1,005
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TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells
2020 · Katherine R. Balka, Cynthia Louis, et al. · Cell Reports · 487
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Mechanism and inhibition of the papain‐like protease, PLpro, of SARS‐CoV‐2
2020 · Theresa Klemm, Gregor Ebert, et al. · The EMBO Journal · 485
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Stressing out the mitochondria: Mechanistic insights into NLRP3 inflammasome activation
2018 · Monica Yabal, Dale J Calleja, et al. · Journal of Leukocyte Biology · 109
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Inhibitors of SARS-CoV-2 PLpro
2022 · Dale J. Calleja, Guillaume Lessene, et al. · Frontiers in Chemistry · 84
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Protein kinase R is an innate immune sensor of proteotoxic stress via accumulation of cytoplasmic IL-24
2022 · Sophia Davidson, Chien-Hsiung Yu, et al. · Science Immunology · 64
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Understanding SOCS protein specificity
2018 · Edmond M. Linossi, Dale J. Calleja, et al. · Growth Factors · 53
Insights Into Drug Repurposing, as Well as Specificity and Compound Properties of Piperidine-Based SARS-CoV-2 PLpro Inhibitors
2022 · Dale J. Calleja, Nathan Kuchel, et al. · Frontiers in Chemistry · 43
A novel PLpro inhibitor improves outcomes in a pre-clinical model of long COVID
2025 · Stefanie M. Bader, Dale J. Calleja, et al. · Nature Communications · 39
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Discovery of an exosite on the SOCS2-SH2 domain that enhances SH2 binding to phosphorylated ligands
2021 · Edmond M. Linossi, Kunlun Li, et al. · Nature Communications · 25
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NLRP1 variant M1184V decreases inflammasome activation in the context of DPP9 inhibition and asthma severity
2020 · Jonas Moecking, Pawat Laohamonthonkul, et al. · Journal of Allergy and Clinical Immunology · 25
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Mutational profiling of SARS-CoV-2 papain-like protease reveals requirements for function, structure, and drug escape
2024 · Xinyu Wu, Margareta Go, et al. · Nature Communications · 21
Characterisation of the OTU domain deubiquitinase complement of Toxoplasma gondii
2023 · Mary-Louise Wilde, Ushma Ruparel, et al. · Life Science Alliance · 15
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TBK1 and IKK epsilon Act Redundantly to Mediate STING-Induced NF-kappa B Responses in Myeloid Cells
2020 · Katherine R. Balka, Cynthia Louis, et al. · Cell Reports · 12
Global analysis of cancer cell responses to USP9X inhibition
2026 · Philipp Schenk, Shane M Devine, et al. · The EMBO Journal · 4
A novel PLpro inhibitor scaffold that protects mice from Long-COVID
2024 · David Komander, Marcel Doerflinger, et al. · Research Square · 1
Author Correction: Discovery of an exosite on the SOCS2-SH2 domain that enhances SH2 binding to phosphorylated ligands
2023 · Edmond M. Linossi, Kunlun Li, et al. · Nature Communications
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Inhibiting SARS-CoV-2 PLpro
2023 · Dale Calleja, David Komander · Acta Crystallographica Section A Foundations and Advances
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Works count: 18
Citation count: 2,467
H-index: 13
I10-index: 14
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