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Lauren A. Hirao
Observed names:
L A Hirao,
L Hirao,
Lauren A Hirao,
Lauren Hirao
Institution:
AstraZeneca (United States)
Observed institutions:
Children's Hospital of Philadelphia,
Bristol-Myers Squibb (United States),
AstraZeneca (United States),
University of Pennsylvania,
University of California, Davis
OpenAlex ID:
A5023788733
Intradermal/subcutaneous immunization by electroporation improves plasmid vaccine delivery and potency in pigs and rhesus macaques
2007
·
Lauren A. Hirao
, Ling Wu
, et al.
·
Vaccine
·
167
Combined effects of IL-12 and electroporation enhances the potency of DNA vaccination in macaques
2008
·
Lauren A. Hirao
, Ling Wu
, et al.
·
Vaccine
·
146
Multivalent Smallpox DNA Vaccine Delivered by Intradermal Electroporation Drives Protective Immunity in Nonhuman Primates Against Lethal Monkeypox Challenge
2010
·
Lauren A. Hirao
, Ruxandra Draghia-Akli
, et al.
·
The Journal of Infectious Diseases
·
106
Epitope-Mapping Studies Define Two Major Neutralization Sites on the Vaccinia Virus Extracellular Enveloped Virus Glycoprotein B5R
2005
·
Lydia Aldaz-Carroll
, J. Charles Whitbeck
, et al.
·
Journal of Virology
·
98
PDF
Th17 cells and regulatory T cells in elite control over HIV and SIV
2011
·
Dennis J Hartigan-OʼConnor
, Lauren A Hirao
, et al.
·
Current Opinion in HIV and AIDS
·
92
Human Immunodeficiency Virus Type 1 Nef Induces Programmed Death 1 Expression through a p38 Mitogen-Activated Protein Kinase-Dependent Mechanism
2008
·
Karuppiah Muthumani
, Andrew Y. Choo
, et al.
·
Journal of Virology
·
81
Early Mucosal Sensing of SIV Infection by Paneth Cells Induces IL-1β Production and Initiates Gut Epithelial Disruption
2014
·
Lauren A. Hirao
, Irina Grishina
, et al.
·
PLoS Pathogens
·
80
PDF
PPARα-targeted mitochondrial bioenergetics mediate repair of intestinal barriers at the host–microbe intersection during SIV infection
2019
·
Katti R. Crakes
, Clarissa Santos Rocha
, et al.
·
Proceedings of the National Academy of Sciences
·
75
PDF
Loss of Multicellular Behavior in Epidemic African Nontyphoidal Salmonella enterica Serovar Typhimurium ST313 Strain D23580
2016
·
Larissa A. Singletary
, Joyce E. Karlinsey
, et al.
·
mBio
·
75
Gut immune dysfunction through impaired innate pattern recognition receptor expression and gut microbiota dysbiosis in chronic SIV infection
2015
·
T W Glavan
, C A Gaulke
, et al.
·
Mucosal Immunology
·
66
PDF
Subclinical Cytomegalovirus Infection Is Associated with Altered Host Immunity, Gut Microbiota, and Vaccine Responses
2018
·
Clarissa Santos Rocha
, Lauren A. Hirao
, et al.
·
Journal of Virology
·
51
PDF
Comparative Analysis of Immune Responses Induced by Vaccination With SIV Antigens by Recombinant Ad5 Vector or Plasmid DNA in Rhesus Macaques
2010
·
Lauren A Hirao
, Ling Wu
, et al.
·
Molecular Therapy
·
47
Muscle as a Target for Supplementary Factor IX Gene Transfer
2007
·
Brad E. Hoffman
, Eric Dobrzynski
, et al.
·
Human Gene Therapy
·
44
Activation drives PD‐1 expression during vaccine‐specific proliferation and following lentiviral infection in macaques
2008
·
David A. Hokey
, F. Brad Johnson
, et al.
·
European Journal of Immunology
·
43
HIV Exploits Antiviral Host Innate GCN2-ATF4 Signaling for Establishing Viral Replication Early in Infection
2017
·
Guochun Jiang
, Clarissa Santos Rocha
, et al.
·
mBio
·
33
PDF
Parameters for DNA vaccination using adaptive constant-current electroporation in mouse and pig models
2008
·
Ruxandra Draghia-Akli
, Amir S. Khan
, et al.
·
Vaccine
·
30
Long-Term Programming of Antigen-Specific Immunity from Gene Expression Signatures in the PBMC of Rhesus Macaques Immunized with an SIV DNA Vaccine
2011
·
Sarah E. Belisle
, Jiangmei Yin
, et al.
·
PLoS ONE
·
25
PDF
Chronic HIV Infection Enhances the Responsiveness of Antigen Presenting Cells to Commensal Lactobacillus
2013
·
Lauren H. Nagy
, Irina Grishina
, et al.
·
PLoS ONE
·
21
PDF
Immune Modulation through 4-1BB Enhances SIV Vaccine Protection in Non-Human Primates against SIVmac251 Challenge
2011
·
Lauren A. Hirao
, David A. Hokey
, et al.
·
PLoS ONE
·
21
PDF
Microbial remodeling of gut tryptophan metabolism and indole-3-lactate production regulate epithelial barrier repair and viral suppression in human and simian immunodeficiency virus infections
2025
·
Clarissa Santos Rocha
, Katie L. Alexander
, et al.
·
Mucosal Immunology
·
19
An optimized SIV DNA vaccine can serve as a boost for Ad5 and provide partial protection from a high-dose SIVmac251 challenge
2012
·
Natalie A. Hutnick
, Devin J.F. Myles
, et al.
·
Vaccine
·
19
Gut germinal center regeneration and enhanced antiviral immunity by mesenchymal stem/stromal cells in SIV infection
2021
·
Mariana G. Weber
, Chara J. Walters-Laird
, et al.
·
JCI Insight
·
17
PDF
Gene expression of Lactobacillus plantarum and the commensal microbiota in the ileum of healthy and early SIV-infected rhesus macaques
2016
·
Benjamin L. Golomb
, Lauren A. Hirao
, et al.
·
Scientific Reports
·
15
PDF
SIV‐infection‐driven changes of pattern recognition receptor expression in mesenteric lymph nodes and gut microbiota dysbiosis
2015
·
Tiffany W. Glavan
, Christopher A. Gaulke
, et al.
·
Journal of Medical Primatology
·
11
CLTA‐4 blockade in vivo promotes the generation of short‐lived effector CD8+ T cells and a more persistent central memory CD4+ T cell response
2008
·
David A. Hokey
, Jian Yan
, et al.
·
Journal of Medical Primatology
·
6
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Works count:
39
Citation count:
1,395
H-index:
19
I10-index:
24
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