Author

Boris Brus

Observed names: B. Brus, Brus, Boris

Observed institution: University of Ljubljana

OpenAlex ID: A5023896672

Discovery, Biological Evaluation, and Crystal Structure of a Novel Nanomolar Selective Butyrylcholinesterase Inhibitor

2014 · Boris Brus, Urban Košak, et al. · Journal of Medicinal Chemistry · 287

Development of an in-vivo active reversible butyrylcholinesterase inhibitor

2016 · Urban Košak, Boris Brus, et al. · Scientific Reports · 178

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The Magic of Crystal Structure-Based Inhibitor Optimization: Development of a Butyrylcholinesterase Inhibitor with Picomolar Affinity and in Vivo Activity

2017 · Urban Košak, Boris Brus, et al. · Journal of Medicinal Chemistry · 168

LiSiCA: A Software for Ligand-Based Virtual Screening and Its Application for the Discovery of Butyrylcholinesterase Inhibitors

2015 · Samo Lešnik, Tanja Štular, et al. · Journal of Chemical Information and Modeling · 91

Development of multifunctional, heterodimeric isoindoline-1,3-dione derivatives as cholinesterase and β-amyloid aggregation inhibitors with neuroprotective properties

2015 · Natalia Guzior, Marek Bajda, et al. · European Journal of Medicinal Chemistry · 69

N-Propargylpiperidines with naphthalene-2-carboxamide or naphthalene-2-sulfonamide moieties: Potential multifunctional anti-Alzheimer’s agents

2016 · Urban Košak, Damijan Knez, et al. · Bioorganic & Medicinal Chemistry · 68

Structure-based development of nitroxoline derivatives as potential multifunctional anti-Alzheimer agents

2015 · Damijan Knez, Boris Brus, et al. · Bioorganic & Medicinal Chemistry · 60

Aggressive conditions during primary drying as a contemporary approach to optimise freeze-drying cycles of biopharmaceuticals

2018 · Maja Bjelošević, Katarina Bolko Seljak, et al. · European Journal of Pharmaceutical Sciences · 55

Isoindoline-1,3-dione derivatives targeting cholinesterases: Design, synthesis and biological evaluation of potential anti-Alzheimer’s agents

2015 · Natalia Guzior, Marek Bajda, et al. · Bioorganic & Medicinal Chemistry · 55

Synthesis of new N-benzylpiperidine derivatives as cholinesterase inhibitors with β-amyloid anti-aggregation properties and beneficial effects on memory in vivo

2015 · Anna Więckowska, Krzysztof Więckowski, et al. · Bioorganic & Medicinal Chemistry · 50

Nonpeptidic Selective Inhibitors of the Chymotrypsin‐Like (β5 i) Subunit of the Immunoproteasome

2016 · Izidor Sosič, Martina Gobec, et al. · Angewandte Chemie International Edition · 47

Novel toll-like receptor 4 (TLR4) antagonists identified by structure- and ligand-based virtual screening

2013 · Urban Švajger, Boris Brus, et al. · European Journal of Medicinal Chemistry · 46

Discovery of new MurA inhibitors using induced-fit simulation and docking

2017 · Kaja Rožman, Samo Lešnik, et al. · Bioorganic & Medicinal Chemistry Letters · 32

The formation and effect of mannitol hemihydrate on the stability of monoclonal antibody in the lyophilized state

2019 · Maja Anko, Maja Bjelošević, et al. · International Journal of Pharmaceutics · 31

Nep1-like proteins as a target for plant pathogen control

2021 · Katja Pirc, Vesna Hodnik, et al. · PLoS Pathogens · 29

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Identification and characterization of the novel reversible and selective cathepsin X inhibitors

2017 · Urša Pečar Fonović, Ana Mitrović, et al. · Scientific Reports · 22

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Straightforward synthesis of orthogonally protected piperidin-3-ylmethanamine and piperidin-4-ylmethanamine derivatives

2014 · Urban Košak, Boris Brus, et al. · Tetrahedron Letters · 17

Expression of human aldo-keto reductase 1C2 in cell lines of peritoneal endometriosis: Potential implications in metabolism of progesterone and dydrogesterone and inhibition by progestins

2012 · Nataša Beranič, Petra Brožič, et al. · The Journal of Steroid Biochemistry and Molecular Biology · 16

Novel Inhibitors of Trihydroxynaphthalene Reductase with Antifungal Activity Identified by Ligand-Based and Structure-Based Virtual Screening

2011 · Mojca Brunskole Švegelj, Samo Turk, et al. · Journal of Chemical Information and Modeling · 14

Multiple Ligands Targeting Cholinesterases and β‐Amyloid: Synthesis, Biological Evaluation of Heterodimeric Compounds with Benzylamine Pharmacophore

2015 · Natalia Szałaj, Marek Bajda, et al. · Archiv der Pharmazie · 12

Discovery of highly potent, nonsteroidal 17β-hydroxysteroid dehydrogenase type 1 inhibitors by virtual high-throughput screening

2011 · Štefan Starčević, Samo Turk, et al. · The Journal of Steroid Biochemistry and Molecular Biology · 12

Synthetic tripeptides as alternate substrates of murein peptide ligase (Mpl)

2012 · Mireille Hervé, Andreja Kovač, et al. · Biochimie · 11

New enzymatic assay for the AKR1C enzymes

2012 · Nataša Beranič, Bogdan Štefane, et al. · Chemico-Biological Interactions · 11

Selective Cytotoxicity of Amidinopiperidine Based Compounds Towards Burkitt’s Lymphoma Cells Involves Proteasome Inhibition

2012 · Martina Gobec, Ales Obreza, et al. · PLoS ONE · 8

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Nonpeptidic Selective Inhibitors of the Chymotrypsin‐Like (β5 i) Subunit of the Immunoproteasome

2016 · Izidor Sosič, Martina Gobec, et al. · Angewandte Chemie · 3

Works count: 35

Citation count: 1,393

H-index: 17

I10-index: 23