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Lukáš Opálka

Observed names: L. Opalka, L. Opálka, Lukas Opalka, Lukáš Opálka, OPALKA Lukas, Opálka, Lukáš, Opálka, Lukáš
Institution: Charles University
ORCID: 0000-0003-1379-1406
Observed ORCID: 0000-0003-1379-1406
OpenAlex ID: A5024149482
Phytosphingosine, sphingosine and dihydrosphingosine ceramides in model skin lipid membranes: permeability and biophysics
2017 · Barbora Školová, Andrej Kováčik, et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 76
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Ceramides in the skin barrier
2017 · K. Vávrová, A. Kováčik, et al. · European Pharmaceutical Journal · 60
PNPLA1 defects in patients with autosomal recessive congenital ichthyosis and KO mice sustain PNPLA1 irreplaceable function in epidermal omega-O-acylceramide synthesis and skin permeability barrier
2017 · Mélanie Pichery, Anne Huchenq, et al. · Human Molecular Genetics · 57
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Stimulation of PPARα normalizes the skin lipid ratio and improves the skin barrier of normal and filaggrin deficient reconstructed skin
2015 · Leonie Wallmeyer, Dominika Lehnen, et al. · Journal of Dermatological Science · 54
HILIC/ESI-MS determination of gangliosides and other polar lipid classes in renal cell carcinoma and surrounding normal tissues
2018 · Roman Hájek, Miroslav Lísa, et al. · Analytical and Bioanalytical Chemistry · 47
Effects of omega-O-acylceramide structures and concentrations in healthy and diseased skin barrier lipid membrane models
2019 · Lukáš Opálka, Andrej Kováčik, et al. · Journal of Lipid Research · 43
The Sphingosine and Acyl Chains of Ceramide [NS] Show Very Different Structure and Dynamics That Challenge Our Understanding of the Skin Barrier
2020 · Oskar Engberg, Andrej Kováčik, et al. · Angewandte Chemie International Edition · 40
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Bacterial immunogenic α-galactosylceramide identified in the murine large intestine: dependency on diet and inflammation
2019 · Johanna von Gerichten, Dominic Lamprecht, et al. · Journal of Lipid Research · 39
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Permeability and microstructure of cholesterol-depleted skin lipid membranes and human stratum corneum
2018 · Michaela Sochorová, Pavla Audrlická, et al. · Journal of Colloid and Interface Science · 37
Omega- O -Acylceramides in Skin Lipid Membranes: Effects of Concentration, Sphingoid Base, and Model Complexity on Microstructure and Permeability
2016 · Lukáš Opálka, Andrej Kováčik, et al. · Langmuir · 37
Non-ionic surfactants as innovative skin penetration enhancers: insight in the mechanism of interaction with simple 2D stratum corneum model system
2020 · Fabio Strati, Reinhard H.H. Neubert, et al. · European Journal of Pharmaceutical Sciences · 36
Scalable Synthesis of Human Ultralong Chain Ceramides
2015 · Lukáš Opálka, Andrej Kováčik, et al. · Organic Letters · 31
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Time-Dependent Differences in the Effects of Oleic Acid and Oleyl Alcohol on the Human Skin Barrier
2023 · Andrej Kováčik, Monika Kopečná, et al. · Molecular Pharmaceutics · 29
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Long and very long lamellar phases in model stratum corneum lipid membranes
2019 · Petra Pullmannová, Elena Ermakova, et al. · Journal of Lipid Research · 27
The effect of long-term cigarette smoking on selected skin barrier proteins and lipids
2023 · Kristýna Hergesell, Anna Paraskevopoulou, et al. · Scientific Reports · 26
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Cellular and Metabolic Basis for the Ichthyotic Phenotype in NIPAL4 (Ichthyin)–Deficient Canines
2018 · Elizabeth A. Mauldin, Debra Crumrine, et al. · American Journal Of Pathology · 26
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Cholesterol sulfate fluidizes the sterol fraction of the stratum corneum lipid phase and increases its permeability
2022 · Ferdinand Fandrei, Oskar Engberg, et al. · Journal of Lipid Research · 23
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Effects of (R)- and (S)-α-Hydroxylation of Acyl Chains in Sphingosine, Dihydrosphingosine, and Phytosphingosine Ceramides on Phase Behavior and Permeability of Skin Lipid Models
2021 · Andrej Kováčik, Petra Pullmannová, et al. · International Journal of Molecular Sciences · 23
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Single Cerebral Organoid Mass Spectrometry of Cell-Specific Protein and Glycosphingolipid Traits
2023 · Markéta Nezvedová, Durga Jha, et al. · Analytical Chemistry · 21
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ω-O-Acylceramides but not ω-hydroxy ceramides are required for healthy lamellar phase architecture of skin barrier lipids
2022 · Lukáš Opálka, Jason M. Meyer, et al. · Journal of Lipid Research · 19
Formation of keto-type ceramides in palmoplantar keratoderma based on biallelic KDSR mutations in patients
2021 · Robert Pilz, Lukáš Opálka, et al. · Human Molecular Genetics · 19
Synthesis of 6-hydroxyceramide using ruthenium-catalyzed hydrosilylation–protodesilylation. Unexpected formation of a long periodicity lamellar phase in skin lipid membranes
2016 · Andrej Kováčik, Lukáš Opálka, et al. · RSC Advances · 19
Effects of imidazolium ionic liquids on skin barrier lipids – Perspectives for drug delivery
2023 · Georgios Paraskevopoulos, Ferdinand Fandrei, et al. · Journal of Colloid and Interface Science · 17
The intriguing molecular dynamics of Cer[EOS] in rigid skin barrier lipid layers requires improvement of the model
2023 · Ferdinand Fandrei, Tomáš Havrišák, et al. · Journal of Lipid Research · 15
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Cerosomes as skin repairing agent: Mode of action studies with a model stratum corneum layer at liquid/air and liquid/solid interfaces
2021 · Fabio Strati, Tetiana Mukhina, et al. · BBA Advances · 15
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Works count: 54
Citation count: 882
H-index: 19
I10-index: 25
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