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George B. Stroup

Observed names: G B Stroup, G STROUP, G Stroup, G. B. Stroup, G. Stroup, G.B Stroup, G.B. Stroup, George B Stroup, George Stroup, Stroup, G.B.
Observed institution: GlaxoSmithKline (United States)
OpenAlex ID: A5024570437
Antagonizing the parathyroid calcium receptor stimulates parathyroid hormone secretion and bone formation in osteopenic rats
2000 · Maxine Gowen, George B. Stroup, et al. · Journal of Clinical Investigation · 280
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Disease-modifying activity of SB 242235, a selective inhibitor of p38 mitogen-activated protein kinase, in rat adjuvant-induced arthritis
2000 · Alison M. Badger, Don E. Griswold, et al. · Arthritis & Rheumatism · 213
Intermittent treatment with parathyroid hormone (PTH) as well as a non-peptide small molecule agonist of the PTH1 receptor inhibits adipocyte differentiation in human bone marrow stromal cells
2006 · David J. Rickard, Fei-Lan Wang, et al. · Bone · 157
Potent and Selective Inhibition of Human Cathepsin K Leads to Inhibition of Bone Resorption In Vivo in a Nonhuman Primate
2001 · George B. Stroup, Michael W. Lark, et al. · Journal of Bone and Mineral Research · 153
A highly potent inhibitor of cathepsin K (relacatib) reduces biomarkers of bone resorption both in vitro and in an acute model of elevated bone turnover in vivo in monkeys
2006 · S. Kumar, L. Dare, et al. · Bone · 137
Discovery of Orally Active Nonpeptide Vitronectin Receptor Antagonists Based on a 2-Benzazepine Gly-Asp Mimetic
1999 · William H. Miller, Doreen P. Alberts, et al. · Journal of Medicinal Chemistry · 120
Applications of micro-CT and MR microscopy to study pre-clinical models of osteoporosis and osteoarthritis
1998 · Rasesh D. Kapadia, George B. Stroup, et al. · Technology and Health Care · 115
Fatty acid and phospholipid selectivity of different phospholipase A2 enzymes studied by using a mammalian membrane as substrate
1994 · E Diez, F H Chilton, et al. · Biochemical Journal · 106
Idoxifene: A Novel Selective Estrogen Receptor Modulator Prevents Bone Loss and Lowers Cholesterol Levels in Ovariectomized Rats and Decreases Uterine Weight in Intact Rats
1998 · Mark E. Nuttall, Jeremy N. Bradbeer, et al. · Endocrinology · 90
An orally active calcium-sensing receptor antagonist that transiently increases plasma concentrations of PTH and stimulates bone formation
2009 · Sanjay Kumar, Christopher J. Matheny, et al. · Bone · 82
A potent small molecule, nonpeptide inhibitor of cathepsin K (SB 331750) prevents bone matrix resorption in the ovariectomized rat
2002 · M.W Lark, G.B Stroup, et al. · Bone · 78
Disease-modifying activity of SB 273005, an orally active, nonpeptide ?v?3 (vitronectin receptor) antagonist, in rat adjuvant-induced arthritis
2001 · Alison M. Badger, Simon Blake, et al. · Arthritis & Rheumatism · 78
Antagonism of the Osteoclast Vitronectin Receptor with an Orally Active Nonpeptide Inhibitor Prevents Cancellous Bone Loss in the Ovariectomized Rat
2001 · Michael W. Lark, George B. Stroup, et al. · Journal of Bone and Mineral Research · 57
Design and Characterization of Orally Active Arg-Gly-Asp Peptidomimetic Vitronectin Receptor Antagonist SB 265123 for Prevention of Bone Loss in Osteoporosis
1999 · Michael W. Lark, George B. Stroup, et al. · Journal of Pharmacology and Experimental Therapeutics · 50
Plasma levels of parathyroid hormone that induce anabolic effects in bone of ovariectomized rats can be achieved by stimulation of endogenous hormone secretion
1997 · J. Fox, M.A. Miller, et al. · Bone · 48
Treatment with a Potent Cathepsin K Inhibitor Preserves Cortical and Trabecular Bone Mass in Ovariectomized Monkeys
2009 · G. B. Stroup, S. Kumar, et al. · Calcified Tissue International · 47
Anti-arthritic activity of hydroxamic acid-based pseudopeptide inhibitors of matrix metalloproteinases and TNFα processing
1997 · M. DiMartino, C. Wolff, et al. · Inflammation Research · 43
Rapid Inhibition of Thyroxine-Induced Bone Resorption in the Rat by an Orally Active Vitronectin Receptor Antagonist
2002 · Sandra J. Hoffman, Janice Vasko-Moser, et al. · Journal of Pharmacology and Experimental Therapeutics · 42
Idoxifene, a Novel Selective Estrogen Receptor Modulator, Is Effective in a Rat Model of Adjuvant-Induced Arthritis
1999 · Alison M. Badger, Simon M. Blake, et al. · Journal of Pharmacology and Experimental Therapeutics · 38
Leucocyte cathepsin K affects atherosclerotic lesion composition and bone mineral density in low-density lipoprotein receptor deficient mice
2008 · J. Guo, I. Bot, et al. · Cardiovascular Research · 36
Orally bioavailable nonpeptide vitronectin receptor antagonists with efficacy in an osteoporosis model
1999 · William H. Miller, William E. Bondinell, et al. · Bioorganic & Medicinal Chemistry Letters · 36
Response to continuous and pulsatile PTH dosing: A mathematical model for parathyroid hormone receptor kinetics
2005 · Laura K. Potter, Larry D. Greller, et al. · Bone · 35
Antagonists of the Calcium Receptor. 2. Amino Alcohol-Based Parathyroid Hormone Secretagogues
2009 · Robert W. Marquis, Amparo M. Lago, et al. · Journal of Medicinal Chemistry · 25
Increased osteoblastogenesis and decreased bone resorption protect against ovariectomy-induced bone loss in thrombospondin-2-null mice
2005 · K HANKENSON, I JAMES, et al. · Matrix Biology · 25
Disease‐modifying activity of SK&F 106615 in rat adjuvant‐induced arthritis. Multiparameter analysis of disease including magnetic resonance imaging and bone mineral density measurements
1996 · Jeremy N. Bradbeer, Rasesh D. Kapadia, et al. · Arthritis & Rheumatism · 23
Works count: 34
Citation count: 2,180
H-index: 24
I10-index: 28
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