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Author

Nan Jiang

ORCID: 0000-0001-5581-929X
Observed ORCID: 0000-0001-5581-929X
OpenAlex ID: A5024836175
Discovery of Novel Indole-Based Allosteric Highly Potent ATX Inhibitors with Great In Vivo Efficacy in a Mouse Lung Fibrosis Model
2020 · Hongrui Lei, Ming Guo, et al. · Journal of Medicinal Chemistry · 38
Microwave-assisted synthesis and biological evaluation of 3,4-diaryl maleic anhydride/N-substituted maleimide derivatives as combretastatin A-4 analogues
2014 · Qi Guan, Daiying Zuo, et al. · Bioorganic & Medicinal Chemistry Letters · 37
Total Synthesis of Bulbophylol-B
2008 · Jinshun Lin, Weige Zhang, et al. · Journal of Natural Products · 35
Recent advances and challenges of revolutionizing drug-resistant tuberculosis treatment
2024 · Xiujian Wei, Lingfeng Yue, et al. · European Journal of Medicinal Chemistry · 30
Design, synthesis and biological evaluation of novel 4-(2-fluorophenoxy)quinoline derivatives as selective c-Met inhibitors
2016 · Xiaoqiang Wang, Nan Jiang, et al. · Bioorganic & Medicinal Chemistry · 30
Design, Synthesis and Antiproliferative Activity of Novel 2-Substituted-4-amino-6-halogenquinolines
2012 · Nan Jiang, Xin Zhai, et al. · Molecules · 27
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Dual potent ALK and ROS1 inhibitors combating drug-resistant mutants: Synthesis and biological evaluation of aminopyridine-containing diarylaminopyrimidine derivatives
2018 · Ming Guo, Daiying Zuo, et al. · European Journal of Medicinal Chemistry · 26
Synthesis and biological evaluation of novel 2-(2-arylmethylene)hydrazinyl-4-aminoquinazoline derivatives as potent antitumor agents
2012 · Nan Jiang, Xin Zhai, et al. · European Journal of Medicinal Chemistry · 26
Discovery of Hybrid Dual N-Acylhydrazone and Diaryl Urea Derivatives as Potent Antitumor Agents: Design, Synthesis and Cytotoxicity Evaluation
2013 · Xin Zhai, Qiang Huang, et al. · Molecules · 24
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Design, Synthesis and Structure-Activity Relationships of Novel Diaryl Urea Derivatives as Potential EGFR Inhibitors
2016 · Nan Jiang, Yanxin Bu, et al. · Molecules · 23
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Discovery of novel mutant-combating ALK and ROS1 dual inhibitors bearing imidazolidin-2-one moiety with reasonable PK properties
2019 · Hongrui Lei, Nan Jiang, et al. · European Journal of Medicinal Chemistry · 20
Catalyst-Free Cyclization- and Curtius Rearrangement-Induced Functional Group Transformation: An Improved Synthetic Strategy of First-in-Class ATX Inhibitor Ziritaxestat (GLPG-1690)
2020 · Hongrui Lei, Yu Yang, et al. · Organic Process Research & Development · 17
Novel hydrazone moiety-bearing aminopyrimidines as selective inhibitors of epidermal growth factor receptor T790M mutant
2015 · Mingze Qin, Tingting Wang, et al. · European Journal of Medicinal Chemistry · 17
Discovery and Optimization of Novel 5-Indolyl-7-arylimidazo[1,2-a]pyridine-8-carbonitrile Derivatives as Potent Antitubulin Agents Targeting Colchicine-binding Site
2017 · Xin Zhai, Xiaoqiang Wang, et al. · Scientific Reports · 16
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Structure guided design of potent indole-based ATX inhibitors bearing hydrazone moiety with tumor suppression effects
2020 · Hongrui Lei, Changtao Li, et al. · European Journal of Medicinal Chemistry · 15
Design, synthesis and promising anti-tumor efficacy of novel imidazo[1,2-a]pyridine derivatives as potent autotaxin allosteric inhibitors
2022 · Hongrui Lei, Xinyu Wang, et al. · European Journal of Medicinal Chemistry · 13
Design, synthesis and anti-inflammatory evaluation of novel pyrrolo[2,3-d]pyrimidin derivatives as potent JAK inhibitors
2019 · Feng Jiang, Linghe Zang, et al. · Bioorganic & Medicinal Chemistry · 13
Discovery of novel 2-phenylamino-4-prolylpyrimidine derivatives as TRK/ALK dual inhibitors with promising antitumor effects
2021 · Tong Li, Changtao Li, et al. · Bioorganic & Medicinal Chemistry · 12
Discovery of Novel 4,5,6,7-Tetrahydro-7H-pyrazolo[3,4-c]pyridin-7-one Derivatives as Orally Efficacious ATX Allosteric Inhibitors for the Treatment of Pulmonary Fibrosis
2024 · Deyi Ma, Zehui Tan, et al. · Journal of Medicinal Chemistry · 11
Structure-based design of 2,4-diaminopyrimidine derivatives bearing a pyrrolyl group as ALK and ROS1 inhibitors
2020 · Jie Wang, Shangfei Wei, et al. · New Journal of Chemistry · 10
Optimization and evaluation of novel tetrahydropyrido[4,3-d]pyrimidine derivatives as ATX inhibitors for cardiac and hepatic fibrosis
2019 · Nan Jiang, Yuhong Zhou, et al. · European Journal of Medicinal Chemistry · 10
An efficient and practical protocol for the production of pretomanid (PA-824) via a novel synthetic strategy
2020 · Guojun Chen, Minglin Zhu, et al. · Chemical Papers · 8
Identification and anti-tumor evaluation of 3-acyl-indol-based 2,4-diarylaminopyrimidine analogues as potent ALK inhibitors capable of overcoming drug-resistant mutants
2022 · Ming Guo, Hao Wang, et al. · European Journal of Medicinal Chemistry · 7
Design, Synthesis and Cytotoxicity of Novel 2-Arylvinyl-4-aminoquinoline Derivatives
2012 · Nan Jiang, Xin Zhai, et al. · Chemical and Pharmaceutical Bulletin · 6
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Discovery of novel pyrazolo[1,5-a]pyrimidine derivatives as selective ROCK2 inhibitors with anti-breast cancer migration and invasion activities
2024 · Zhi Cao, Xiujian Wei, et al. · Bioorganic Chemistry · 5
Works count: 37
Citation count: 500
H-index: 15
I10-index: 21
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