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Andrew L. Metcalfe
Observed names:
A L Metcalfe,
Andrew L Metcalfe,
Andrew Metcalfe,
Metcalfe, Andrew
Institution:
Pancreas Centre (Canada)
Observed institutions:
BC Cancer Agency,
Beth Israel Deaconess Medical Center,
Agriculture and Agri-Food Canada,
Harvard University,
University of British Columbia,
Pancreas Centre (Canada),
Summerland Research and Development Centre
show all 7
ORCID:
0000-0001-9292-8778
Observed ORCID:
0000-0001-9292-8778
OpenAlex ID:
A5025091949
Altered Gene Expression along the Glycolysis–Cholesterol Synthesis Axis Is Associated with Outcome in Pancreatic Cancer
2019
·
Joanna M. Karasinska
, James T. Topham
, et al.
·
Clinical Cancer Research
·
216
Focused Magnetic Stem Cell Targeting to the Retina Using Superparamagnetic Iron Oxide Nanoparticles
2012
·
Anat Yanai
, Urs O. Häfeli
, et al.
·
Cell Transplantation
·
148
Genome-wide synthetic lethal screen unveils novel CAIX-NFS1/xCT axis as a targetable vulnerability in hypoxic solid tumors
2021
·
Shawn C. Chafe
, Frederick S. Vizeacoumar
, et al.
·
Science Advances
·
145
PDF
Postnatal manipulation of Pax6 dosage reverses congenital tissue malformation defects
2013
·
Cheryl Y. Gregory-Evans
, Xia Wang
, et al.
·
Journal of Clinical Investigation
·
117
NLRP3 inflammasome activation drives bystander cone photoreceptor cell death in a P23H rhodopsin model of retinal degeneration
2016
·
Ishaq A. Viringipurampeer
, Andrew L. Metcalfe
, et al.
·
Human Molecular Genetics
·
92
PDF
Integrative analysis of KRAS wildtype metastatic pancreatic ductal adenocarcinoma reveals mutation and expression-based similarities to cholangiocarcinoma
2022
·
James T. Topham
, Erica S. Tsang
, et al.
·
Nature Communications
·
44
PDF
Characterization of Staphylococcus xylosus isolated from broiler chicken barn bioaerosol
2012
·
Javier Vela
, Kelsie Hildebrandt
, et al.
·
Poultry Science
·
33
PDF
Cell Death Pathways in Mutant Rhodopsin Rat Models Identifies Genotype-Specific Targets Controlling Retinal Degeneration
2018
·
Ishaq A. Viringipurampeer
, Cheryl Y. Gregory-Evans
, et al.
·
Molecular Neurobiology
·
27
Investigation of Nano-Bio Interactions within a Pancreatic Tumor Microenvironment for the Advancement of Nanomedicine in Cancer Treatment
2021
·
Abdulaziz Alhussan
, Kyle Bromma
, et al.
·
Current Oncology
·
17
PDF
An ex vivo gene therapy approach in X-linked retinoschisis.
2016
·
Abu E Bashar
, Andrew L Metcalfe
, et al.
·
PubMed Central
·
17
PDF
Influence of Iron Oxide Nanoparticles on Innate and Genetically Modified Secretion Profiles of Mesenchymal Stem Cells
2012
·
Abu Emran Bashar
, Andrew Metcalfe
, et al.
·
IEEE Transactions on Magnetics
·
10
Bimodal in vivo imaging provides early assessment of stem-cell-based photoreceptor engraftment
2015
·
C R J Laver
, A L Metcalfe
, et al.
·
Eye
·
9
Abstract A24: Gene expression along the glycolysis-cholesterol synthesis axis and outcome in pancreatic cancer
2019
·
Joanna M. Karasinska
, James T. Topham
, et al.
·
Cancer Research
·
2
Abstract 4596: Spatial transcriptomics reveals subtype heterogeneity within the tumor epithelial compartment of pancreatic ductal adenocarcinoma
2025
·
James Topham
, Jenny Chu
, et al.
·
Cancer Research
Abstract C109: Nanostring-based subtyping of pancreatic ductal adenocarcinoma is strongly influenced by the stromal compartment
2024
·
James T. Topham
, Steve E. Kalloger
, et al.
·
Cancer Research
Abstract B053: Targeting SMURF1 with low-dose proteasome inhibitors in pancreatic cancer organoids
2022
·
Andrew Metcalfe
, Joanna M. Karasinska
, et al.
·
Cancer Research
Abstract LB129: Analysis of KRAS wildtype pancreatic ductal adenocarcinoma reveals mutation and expression-based similarities to cholangiocarcinoma
2022
·
James Topham
, Erica Tsang
, et al.
·
Cancer Research
Abstract PO-021: Targeting the mitochondrial pyruvate complex to alter metabolic programming in pancreatic cancer
2021
·
Hassan A. Ali
, Andrew Metcalfe
, et al.
·
Cancer Research
A road map to exploit the tumor microenvironment for the advancement of “smart” nanomedicines in treating pancreatic cancer
2021
·
Abdulaziz Alhussan
, Kyle Bromma
, et al.
Pharmacological nonsense suppression therapy in Rpe65-/- mouse model of Leber congenital amaurosis reverses the retinal functional deficits in vivo
2015
·
Xia Wang
, Olena Sivak
, et al.
·
Investigative Ophthalmology & Visual Science
RIP3-induced NLRP3 inflammasome activation is the major driver for P23H rhodopsin photoreceptor degeneration
2015
·
Cheryl Y. Gregory‐Evans
, Ishaq A. Viringipurampeer
, et al.
·
Investigative Ophthalmology & Visual Science
Postnatal nonsense suppression therapy rescues Pax6-deficient congenital eye defects
2014
·
Xia Wang
, Andrew Metcalfe
, et al.
·
Investigative Ophthalmology & Visual Science
Optimized cell-handling of human embryonic stem cells in the differentiation of photoreceptor precursor cells
2013
·
Christopher Laver
, Anat Yanai
, et al.
·
Investigative Ophthalmology & Visual Science
Topical small molecule translational bypass therapy rescues Pax6 aniridia mutant phenotype
2013
·
Cheryl Y. Gregory‐Evans
, Xia Wang
, et al.
·
Investigative Ophthalmology & Visual Science
Mesenchymal stem cell based ex vivo gene therapy provides enhanced neuroprotection in X-linked retinoschisis mouse model
2013
·
Ama Bashar
, Andrew Metcalfe
, et al.
·
Investigative Ophthalmology & Visual Science
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Works count:
32
Citation count:
877
H-index:
10
I10-index:
11
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