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Holger Hess‐Stumpp

Observed names: H Hess-Stumpp, H. Hess-Stumpp, H. Hess‐Stumpp, Hess-Stumpp, H., Hess-Stumpp, Holger, Holger Hess-Stump, Holger Hess-Stumpp
ORCID: 0000-0001-9955-6583
Observed ORCID: 0000-0001-9955-6583
OpenAlex ID: A5025093282
Suppression of antitumor T cell immunity by the oncometabolite (R)-2-hydroxyglutarate
2018 · Lukas Bunse, Stefan Pusch, et al. · Nature Medicine · 561
Acetyl-CoA Carboxylase 1-Dependent Protein Acetylation Controls Breast Cancer Metastasis and Recurrence
2017 · Marcos Rios Garcia, Brigitte Steinbauer, et al. · Cell Metabolism · 281
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BAY 87‐2243, a highly potent and selective inhibitor of hypoxia‐induced gene activation has antitumor activities by inhibition of mitochondrial complex I
2013 · Peter Ellinghaus, Iring Heisler, et al. · Cancer Medicine · 233
In vivo properties of an anti-GnRH Spiegelmer: An example of an oligonucleotide-based therapeutic substance class
2002 · Britta Wlotzka, Susanne Leva, et al. · Proceedings of the National Academy of Sciences · 187
Pan-mutant IDH1 inhibitor BAY 1436032 for effective treatment of IDH1 mutant astrocytoma in vivo
2017 · Stefan Pusch, Sonja Krausert, et al. · Acta Neuropathologica · 179
MS-275, a potent orally available inhibitor of histone deacetylases—The development of an anticancer agent
2007 · Holger Hess-Stumpp, Tomke Ute Bracker, et al. · The International Journal of Biochemistry & Cell Biology · 156
Pan-mutant-IDH1 inhibitor BAY1436032 is highly effective against human IDH1 mutant acute myeloid leukemia in vivo
2017 · A Chaturvedi, L Herbst, et al. · Leukemia · 125
Histone deacetylase inhibitors and cancer: from cell biology to the clinic
2005 · Holger Hess-Stumpp · European Journal of Cell Biology · 117
Asoprisnil (J867): a selective progesterone receptor modulator for gynecological therapy
2003 · Deborah DeManno, Walter Elger, et al. · Steroids · 111
Mass cytometry analysis reveals a distinct immune environment in peritoneal fluid in endometriosis: a characterisation study
2020 · Manman Guo, Cemsel Bafligil, et al. · BMC Medicine · 98
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Rogaratinib: A potent and selective pan‐FGFR inhibitor with broad antitumor activity in FGFR‐overexpressing preclinical cancer models
2019 · Sylvia Grünewald, Oliver Politz, et al. · International Journal of Cancer · 98
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Synthesis and Biological Activity of a Novel, Highly Potent Progesterone Receptor Antagonist
2000 · Ulrike Fuhrmann, Holger Hess-Stumpp, et al. · Journal of Medicinal Chemistry · 98
The branched-chain amino acid transaminase 1 sustains growth of antiestrogen-resistant and ERα-negative breast cancer
2017 · V Thewes, R Simon, et al. · Oncogene · 90
Sagopilone crosses the blood–brain barrier in vivo to inhibit brain tumor growth and metastases
2008 · Jens Hoffmann, Iduna Fichtner, et al. · Neuro-Oncology · 78
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BAY 87–2243, a novel inhibitor of hypoxia-induced gene activation, improves local tumor control after fractionated irradiation in a schedule-dependent manner in head and neck human xenografts
2014 · Linda Helbig, Lydia Koi, et al. · Radiation Oncology · 66
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Discovery of Rogaratinib (BAY 1163877): a pan‐FGFR Inhibitor
2018 · Marie‐Pierre Collin, Mario Lobell, et al. · ChemMedChem · 63
PTK 787/ZK 222584, a Tyrosine Kinase Inhibitor of all Known VEGF Receptors, Represses Tumor Growth with High Efficacy
2005 · Holger Hess‐Stumpp, Martin Haberey, et al. · ChemBioChem · 62
Neuropeptide S receptor 1 is a nonhormonal treatment target in endometriosis
2021 · Thomas T. Tapmeier, Nilufer Rahmioglu, et al. · Science Translational Medicine · 56
TGF-β1 Potentiates Adoptive Immunotherapy of Hematological and Solid Tumors Using ex vivo Expanded γδ T-Cells
2021 · Richard E. Beatson, Ana C. Parente-Pereira, et al. · Cell Reports Medicine · 44
Lethal Poisoning of Cancer Cells by Respiratory Chain Inhibition plus Dimethyl α-Ketoglutarate
2019 · Valentina Sica, Jose Manuel Bravo-San Pedro, et al. · Cell Reports · 44
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Inhibition of Multiple Vascular Endothelial Growth Factor Receptors (VEGFR) Blocks Lymph Node Metastases but Inhibition of VEGFR-2 Is Sufficient to Sensitize Tumor Cells to Platinum-Based Chemotherapeutics
2008 · Patrizia Sini, Ivana Samarzija, et al. · Cancer Research · 37
LDH-A influences hypoxia-inducible factor 1α (HIF1 α) and is critical for growth of HT29 colon carcinoma cells in vivo
2011 · Stefan Langhammer, Maher Najjar, et al. · Targeted Oncology · 36
Hypoxia-Inducible Factor Pathway Inhibition Resolves Tumor Hypoxia and Improves Local Tumor Control After Single-Dose Irradiation
2013 · Linda Helbig, Lydia Koi, et al. · International Journal of Radiation Oncology*Biology*Physics · 35
SIAH ubiquitin ligases regulate breast cancer cell migration and invasion independent of the oxygen status
2015 · M Gordian Adam, Sonja Matt, et al. · Cell Cycle · 34
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Amine oxidase 3 is a novel pro-inflammatory marker of oxidative stress in peritoneal endometriosis lesions
2020 · Marie-Laëtitia Thézénas, Bianca De Leo, et al. · Scientific Reports · 33
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Works count: 73
Citation count: 3,040
H-index: 25
I10-index: 30
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