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Khurrum Shahzad

Nlrp3-inflammasome activation in non-myeloid-derived cells aggravates diabetic nephropathy
2014 · Khurrum Shahzad, Fabian Bock, et al. · Kidney International · 411
Maternal extracellular vesicles and platelets promote preeclampsia via inflammasome activation in trophoblasts
2016 · Shrey Kohli, Satish Ranjan, et al. · Blood · 188
Defective podocyte insulin signalling through p85-XBP1 promotes ATF6-dependent maladaptive ER-stress response in diabetic nephropathy
2015 · Thati Madhusudhan, Hongjie Wang, et al. · Nature Communications · 182
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Podocyte-specific Nlrp3 inflammasome activation promotes diabetic kidney disease
2022 · Khurrum Shahzad, Sameen Fatima, et al. · Kidney International · 172
Cytoprotective activated protein C averts Nlrp3 inflammasome–induced ischemia-reperfusion injury via mTORC1 inhibition
2017 · Sumra Nazir, Ihsan Gadi, et al. · Blood · 158
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Activated protein C ameliorates diabetic nephropathy by epigenetically inhibiting the redox enzyme p66 Shc
2012 · Fabian Bock, Khurrum Shahzad, et al. · Proceedings of the National Academy of Sciences · 141
Cytoprotective signaling by activated protein C requires protease-activated receptor-3 in podocytes
2011 · Thati Madhusudhan, Hongjie Wang, et al. · Blood · 127
Caspase-1, but Not Caspase-3, Promotes Diabetic Nephropathy
2016 · Khurrum Shahzad, Fabian Bock, et al. · Journal of the American Society of Nephrology · 125
Evaluation of Plaque Stability of Advanced Atherosclerotic Lesions in Apo E-Deficient Mice after Treatment with the Oral Factor Xa Inhibitor Rivaroxaban
2011 · Qianxing Zhou, Florian Bea, et al. · Mediators of Inflammation · 124
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Neutrophil Extracellular Traps Promote NLRP3 Inflammasome Activation and Glomerular Endothelial Dysfunction in Diabetic Kidney Disease
2022 · Anubhuti Gupta, Kunal Singh, et al. · Nutrients · 119
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Stabilization of endogenous Nrf2 by minocycline protects against Nlrp3-inflammasome induced diabetic nephropathy
2016 · Khurrum Shahzad, Fabian Bock, et al. · Scientific Reports · 91
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Reversal of the renal hyperglycemic memory in diabetic kidney disease by targeting sustained tubular p21 expression
2022 · Moh’d Mohanad Al-Dabet, Khurrum Shahzad, et al. · Nature Communications · 86
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Activated Protein C Ameliorates Renal Ischemia-Reperfusion Injury by Restricting Y-Box Binding Protein-1 Ubiquitination
2015 · Wei Dong, Hongjie Wang, et al. · Journal of the American Society of Nephrology · 82
Farnesoid X Receptor Agonism Protects against Diabetic Tubulopathy: Potential Add-On Therapy for Diabetic Nephropathy
2017 · Andi Marquardt, Moh’d Mohanad Al-Dabet, et al. · Journal of the American Society of Nephrology · 72
Hypercoagulability Inhibits Monocyte Transendothelial Migration Through Protease-Activated Receptor-1-, Phospholipase-Cβ-, Phosphoinositide 3-Kinase-, and Nitric Oxide-Dependent Signaling in Monocytes and Promotes Plaque Stability
2009 · Stefanie Seehaus, Khurrum Shahzad, et al. · Circulation · 68
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The lectin-like domain of thrombomodulin ameliorates diabetic glomerulopathy via complement inhibition
2012 · Ilya Vinnikov, Khurrum Shahzad, et al. · Thrombosis and Haemostasis · 61
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Thrombosis and Inflammation—A Dynamic Interplay and the Role of Glycosaminoglycans and Activated Protein C
2022 · Shrey Kohli, Khurrum Shahzad, et al. · Frontiers in Cardiovascular Medicine · 50
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Low but sustained coagulation activation ameliorates glucose-induced podocyte apoptosis: protective effect of factor V Leiden in diabetic nephropathy
2011 · Hongjie Wang, Thati Madhusudhan, et al. · Blood · 48
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Thrombin-Induced Podocyte Injury Is Protease-Activated Receptor Dependent
2017 · Ruchika Sharma, Amanda P. Waller, et al. · Journal of the American Society of Nephrology · 46
Activated protein C protects from GvHD via PAR2/PAR3 signalling in regulatory T-cells
2017 · Satish Ranjan, Alexander Goihl, et al. · Nature Communications · 44
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Different DOACs Control Inflammation in Cardiac Ischemia-Reperfusion Differently
2020 · Ihsan Gadi, Sameen Fatima, et al. · Circulation Research · 42
Chronic kidney disease leads to microglial potassium efflux and inflammasome activation in the brain
2024 · Silke Zimmermann, Akash Mathew, et al. · Kidney International · 41
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Activated protein C reverses epigenetically sustained p66Shc expression in plaque-associated macrophages in diabetes
2018 · Khurrum Shahzad, Ihsan Gadi, et al. · Communications Biology · 40
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Cell biology of activated protein C
2018 · Khurrum Shahzad, Shrey Kohli, et al. · Current Opinion in Hematology · 36
p45NF-E2 represses Gcm1 in trophoblast cells to regulate syncytium formation, placental vascularization and embryonic growth
2011 · Muhammed Kashif, Andrea Hellwig, et al. · Development · 32
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Works count: 79
Citation count: 3,015
H-index: 28
I10-index: 43
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