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Jaeseok Han

ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death
2013 · Jaeseok Han, Sung Hoon Back, et al. · Nature Cell Biology · 1,738
The role of ER stress in lipid metabolism and lipotoxicity
2016 · Jaeseok Han, Randal J. Kaufman · Journal of Lipid Research · 664
Translation Attenuation through eIF2α Phosphorylation Prevents Oxidative Stress and Maintains the Differentiated State in β Cells
2009 · Sung Hoon Back, Donalyn Scheuner, et al. · Cell Metabolism · 368
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IRE1α-XBP1s Induces PDI Expression to Increase MTP Activity for Hepatic VLDL Assembly and Lipid Homeostasis
2012 · Shiyu Wang, Zhouji Chen, et al. · Cell Metabolism · 245
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Therapeutic opportunities for pancreatic β-cell ER stress in diabetes mellitus
2021 · Jing Yong, James D. Johnson, et al. · Nature Reviews Endocrinology · 240
The IRE1α/XBP1s Pathway Is Essential for the Glucose Response and Protection of β Cells
2015 · Justin R. Hassler, Donalyn L. Scheuner, et al. · PLoS Biology · 207
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HLA-DR4-IE chimeric class II transgenic, murine class II-deficient mice are susceptible to experimental allergic encephalomyelitis.
1996 · K Ito, H J Bian, et al. · The Journal of Experimental Medicine · 193
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Glucagon-Like Peptide-1 Gene Therapy in Obese Diabetic Mice Results in Long-Term Cure of Diabetes by Improving Insulin Sensitivity and Reducing Hepatic Gluconeogenesis
2007 · Young-Sun Lee, Seungjin Shin, et al. · Diabetes · 161
Translational and posttranslational regulation of XIAP by eIF2α and ATF4 promotes ER stress–induced cell death during the unfolded protein response
2014 · Nobuhiko Hiramatsu, Carissa Messah, et al. · Molecular Biology of the Cell · 135
The unfolded protein response is required to maintain the integrity of the endoplasmic reticulum, prevent oxidative stress and preserve differentiation in β ‐cells
2010 · R. J. Kaufman, S. H. Back, et al. · Diabetes Obesity and Metabolism · 130
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Physiological/pathological ramifications of transcription factors in the unfolded protein response
2017 · Jaeseok Han, Randal J. Kaufman · Genes & Development · 120
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A Self-defeating Anabolic Program Leads to β-Cell Apoptosis in Endoplasmic Reticulum Stress-induced Diabetes via Regulation of Amino Acid Flux
2013 · Dawid Krokowski, Jaeseok Han, et al. · Journal of Biological Chemistry · 117
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ER stress signalling through eIF2α and CHOP, but not IRE1α, attenuates adipogenesis in mice
2013 · J. Han, R. Murthy, et al. · Diabetologia · 116
Mitophagy deficiency increases NLRP3 to induce brown fat dysfunction in mice
2020 · Myoung Seok Ko, Ji Young Yun, et al. · Autophagy · 112
RNA surveillance is required for endoplasmic reticulum homeostasis
2012 · Kenjiro Sakaki, Sawako Yoshina, et al. · Proceedings of the National Academy of Sciences · 96
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ER Stress Induces Cell Cycle Arrest at the G2/M Phase Through eIF2α Phosphorylation and GADD45α
2019 · Duckgue Lee, Daniel Hokinson, et al. · International Journal of Molecular Sciences · 89
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Effect of p38 Mitogen-Activated Protein Kinase on the Replication of Encephalomyocarditis Virus
2003 · Kensuke Hirasawa, Angus Kim, et al. · Journal of Virology · 78
TMBIM6/BI-1 contributes to cancer progression through assembly with mTORC2 and AKT activation
2020 · Hyun-Kyoung Kim, Kashi Raj Bhattarai, et al. · Nature Communications · 73
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Endoplasmic Reticulum Stress in theβ-Cell Pathogenesis of Type 2 Diabetes
2011 · Sung Hoon Back, Sang-Wook Kang, et al. · Experimental Diabetes Research · 67
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Selective Transcriptional Regulations in the Human Liver Cell by Hepatitis B Viral X Protein
2000 · Jaeseok Han, Hae Yong Yoo, et al. · Biochemical and Biophysical Research Communications · 59
C/EBP-Homologous Protein (CHOP) in Vascular Smooth Muscle Cells Regulates Their Proliferation in Aortic Explants and Atherosclerotic Lesions
2015 · Alex-Xianghua Zhou, Xiaobo Wang, et al. · Circulation Research · 58
Antioxidants Complement the Requirement for Protein Chaperone Function to Maintain β-Cell Function and Glucose Homeostasis
2015 · Jaeseok Han, Benbo Song, et al. · Diabetes · 52
Stress Granule Formation Attenuates RACK1-Mediated Apoptotic Cell Death Induced by Morusin
2020 · Ye-Jin Park, Dong Wook Choi, et al. · International Journal of Molecular Sciences · 49
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Remission of Diabetes by Insulin Gene Therapy Using a Hepatocyte-specific and Glucose-responsive Synthetic Promoter
2010 · Jaeseok Han, Brienne McLane, et al. · Molecular Therapy · 48
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Gamma Interferon Paradoxically Inhibits the Development of Diabetes in the NOD Mouse
2002 · Douglas O. Sobel, Jaeseok Han, et al. · Journal of Autoimmunity · 47
Works count: 67
Citation count: 5,918
H-index: 32
I10-index: 48
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