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Ashok Sekhar

Observed name: Sekhar, Ashok
ORCID: 0000-0002-8628-7799
Observed ORCID: 0000-0002-8628-7799
OpenAlex ID: A5025494876
Structural and hydrodynamic properties of an intrinsically disordered region of a germ cell-specific protein on phase separation
2017 · Jacob P. Brady, Patrick J. Farber, et al. · Proceedings of the National Academy of Sciences · 534
NMR paves the way for atomic level descriptions of sparsely populated, transiently formed biomolecular conformers
2013 · Ashok Sekhar, Lewis E. Kay · Proceedings of the National Academy of Sciences · 253
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An NMR View of Protein Dynamics in Health and Disease
2019 · Ashok Sekhar, Lewis E. Kay · Annual Review of Biophysics · 178
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Probing conformational dynamics in biomolecules via chemical exchange saturation transfer: a primer
2017 · Pramodh Vallurupalli, Ashok Sekhar, et al. · Journal of Biomolecular NMR · 163
Thermal fluctuations of immature SOD1 lead to separate folding and misfolding pathways
2015 · Ashok Sekhar, Jessica AO Rumfeldt, et al. · eLife · 115
Hsp70 biases the folding pathways of client proteins
2016 · Ashok Sekhar, Rina Rosenzweig, et al. · Proceedings of the National Academy of Sciences · 109
Mapping the conformation of a client protein through the Hsp70 functional cycle
2015 · Ashok Sekhar, Rina Rosenzweig, et al. · Proceedings of the National Academy of Sciences · 95
Promiscuous binding by Hsp70 results in conformational heterogeneity and fuzzy chaperone-substrate ensembles
2017 · Rina Rosenzweig, Ashok Sekhar, et al. · eLife · 94
Conserved conformational selection mechanism of Hsp70 chaperone-substrate interactions
2018 · Ashok Sekhar, Algirdas Velyvis, et al. · eLife · 80
Effects of maturation on the conformational free-energy landscape of SOD1
2018 · Robert M. Culik, Ashok Sekhar, et al. · Proceedings of the National Academy of Sciences · 67
Probing the free energy landscapes of ALS disease mutants of SOD1 by NMR spectroscopy
2016 · Ashok Sekhar, Jessica A. O. Rumfeldt, et al. · Proceedings of the National Academy of Sciences · 57
Understanding the mechanism of proteasome 20S core particle gating
2014 · Michael P. Latham, Ashok Sekhar, et al. · Proceedings of the National Academy of Sciences · 55
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Heterogeneous binding of the SH3 client protein to the DnaK molecular chaperone
2015 · Jung Ho Lee, Dongyu Zhang, et al. · Proceedings of the National Academy of Sciences · 54
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A Universal Pattern in the Percolation and Dissipation of Protein Structural Perturbations
2017 · Nandakumar Rajasekaran, Ashok Sekhar, et al. · The Journal of Physical Chemistry Letters · 53
1 H-Detected 13 C Photo-CIDNP as a Sensitivity Enhancement Tool in Solution NMR
2011 · Jung Ho Lee, Ashok Sekhar, et al. · Journal of the American Chemical Society · 53
Characterizing Post-Translational Modifications and Their Effects on Protein Conformation Using NMR Spectroscopy
2019 · Ajith Kumar, Vaishali Narayanan, et al. · Biochemistry · 52
Separating Dipolar and Chemical Exchange Magnetization Transfer Processes in 1 H‐CEST
2016 · Tairan Yuwen, Ashok Sekhar, et al. · Angewandte Chemie International Edition · 52
Functional regulation of an intrinsically disordered protein via a conformationally excited state
2023 · Kulkarni Madhurima, Bodhisatwa Nandi, et al. · Science Advances · 40
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Concurrent Increases and Decreases in Local Stability and Conformational Heterogeneity in Cu, Zn Superoxide Dismutase Variants Revealed by Temperature-Dependence of Amide Chemical Shifts
2016 · Colleen M. Doyle, Jessica A. Rumfeldt, et al. · Biochemistry · 38
Triple resonance-based 13Cα and 13Cβ CEST experiments for studies of ms timescale dynamics in proteins
2014 · Dong Long, Ashok Sekhar, et al. · Journal of Biomolecular NMR · 34
Probing the Free Energy Landscape of the Fast-Folding gpW Protein by Relaxation Dispersion NMR
2014 · Celia Sanchez-Medina, Ashok Sekhar, et al. · Journal of the American Chemical Society · 34
Defining a length scale for millisecond-timescale protein conformational exchange
2013 · Ashok Sekhar, Pramodh Vallurupalli, et al. · Proceedings of the National Academy of Sciences · 32
Viscosity-Dependent Kinetics of Protein Conformational Exchange: Microviscosity Effects and the Need for a Small Viscogen
2014 · Ashok Sekhar, Michael P. Latham, et al. · The Journal of Physical Chemistry B · 31
Probing Invisible, Excited Protein States by Non‐Uniformly Sampled Pseudo‐4D CEST Spectroscopy
2015 · Dong Long, Frank Delaglio, et al. · Angewandte Chemie International Edition · 30
Metamorphic proteins: the Janus proteins of structural biology
2021 · Kulkarni Madhurima, Bodhisatwa Nandi, et al. · Open Biology · 29
Works count: 79
Citation count: 2,657
H-index: 26
I10-index: 41
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