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Xiaozhang Xu
Observed name:
Xiao-Zhang Xu
Institutions:
Huaian First People’s Hospital,
Nanjing Medical University
Observed institutions:
Chinese Academy of Medical Sciences & Peking Union Medical College,
Huaian First People’s Hospital,
Jiangsu Province Hospital,
Nanjing Medical University
ORCID:
0000-0001-6756-8483
Observed ORCID:
0000-0001-6756-8483
OpenAlex ID:
A5025500614
Tumor metabolite lactate promotes tumorigenesis by modulating MOESIN lactylation and enhancing TGF-β signaling in regulatory T cells
2022
·
Jian Gu
, Jinren Zhou
, et al.
·
Cell Reports
·
562
Tumor-resident microbiota contributes to colorectal cancer liver metastasis by lactylation and immune modulation
2024
·
Jian Gu
, Xiaozhang Xu
, et al.
·
Oncogene
·
154
Tumor metabolite lactate promotes tumorigenesis by modulating MOESIN lactylation and enhancing TGF-β signaling in regulatory T cells
2022
·
Jian Gu
, Jinren Zhou
, et al.
·
Cell Reports
·
87
Lactate supports Treg function and immune balance via MGAT1 effects on N-glycosylation in the mitochondria
2024
·
Jinren Zhou
, Jian Gu
, et al.
·
Journal of Clinical Investigation
·
70
PDF
Tumor-produced ammonia is metabolized by regulatory T cells to further impede anti-tumor immunity
2025
·
Jian Gu
, Yu Li
, et al.
·
Cell
·
51
Monocarboxylate transporter upregulation in induced regulatory T cells promotes resistance to anti-PD-1 therapy in hepatocellular carcinoma patients
2022
·
Jinren Zhou
, Qing Shao
, et al.
·
Frontiers in Oncology
·
32
PDF
Orosomucoid 1 promotes colorectal cancer progression and liver metastasis by affecting PI3K/AKT pathway and inducing macrophage M2 polarization
2023
·
Lei Yue
, Xiaozhang Xu
, et al.
·
Scientific Reports
·
23
PDF
miR-455/GREM1 axis promotes colorectal cancer progression and liver metastasis by affecting PI3K/AKT pathway and inducing M2 macrophage polarization
2024
·
Shipeng Dai
, Fan Xu
, et al.
·
Cancer Cell International
·
22
Integrated single-cell and spatial transcriptomic profiling reveals that CD177+ Tregs enhance immunosuppression through apoptosis and resistance to immunotherapy in hepatocellular carcinoma
2025
·
Yuan Liang
, Lei Qiao
, et al.
·
Oncogene
·
13
Correction: Tumor-resident microbiota contributes to colorectal cancer liver metastasis by lactylation and immune modulation
2025
·
Jian Gu
, Xiaozhang Xu
, et al.
·
Oncogene
·
8
PDF
Synchronous parathyroid adenoma, papillary thyroid carcinoma and thyroid adenoma in pregnancy: A case report
2020
·
Qiang Li
, Xiao-Zhang Xu
, et al.
·
World Journal of Clinical Cases
·
7
PSME3 drives Tregs infiltration and anti-PD1 resistance in hepatocellular carcinoma by regulating FBXL7/PTEN-mediated metabolic reprogramming
2025
·
Qiuyang Chen
, Yuan Liang
, et al.
·
Oncogene
·
5
ATG16L1 Depletion‐Mediated Activation of the TRAF1 Signaling in Macrophages Aggravates Liver Fibrosis
2024
·
Yufeng Pan
, Yi Wei
, et al.
·
Mediators of Inflammation
·
1
PDF
The Bacterial Metabolite Lndole-3-Propionic Acid Alleviates Acetaminophen-Induced Acute Liver Injury Partly through the Aryl Hydrocarbon Receptor Pathway
2026
·
Bo Zhou
, Xiushang Ye
, et al.
·
Journal of Microbiology and Biotechnology
PDF
SP1‐Driven SPP1 + Senescent Macrophages Orchestrate an Immunosuppressive Microenvironment in Triple‐Negative Breast Cancer
2026
·
Yuting Liu
, Jingjing Zhang
, et al.
·
Human Mutation
P.03: CD38 promotes regulatory T Cell survival and immunosuppression via calcium/Ras/GGT1 pathway activation to attenuate ROS post-transplantation.
2025
·
Yunjie Lu
, Jinren Zhou
, et al.
·
Transplantation
[68Ga]Ga-HM or [68Ga]Ga-PM: Which Is Superior for PET/CT Imaging of HMGB1-Positive Tumors?
2025
·
Kunyao Wang
, Wenqi Zhao
, et al.
·
Molecular Pharmaceutics
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Works count:
17
Citation count:
1,035
H-index:
9
I10-index:
9
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