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Samuel Desta Guma
Observed names:
Samuel Desta,
Samuel Guma
Institutions:
Shandong University,
Chinese Academy of Sciences,
Shanghai Institute of Materia Medica,
University of Chinese Academy of Sciences,
State Key Laboratory of Drug Research
Observed institutions:
Shandong University,
Chinese Academy of Sciences,
Shanghai Institute of Materia Medica,
University of Chinese Academy of Sciences,
State Key Laboratory of Drug Research
ORCID:
0009-0005-0082-5808
Observed ORCID:
0009-0005-0082-5808
OpenAlex ID:
A5025674068
Optimization of N-Substituted Oseltamivir Derivatives as Potent Inhibitors of Group-1 and -2 Influenza A Neuraminidases, Including a Drug-Resistant Variant
2018
·
Jian Zhang
, Vasanthanathan Poongavanam
, et al.
·
Journal of Medicinal Chemistry
·
63
Exploring the hydrophobic channel of NNIBP leads to the discovery of novel piperidine-substituted thiophene[3,2-d]pyrimidine derivatives as potent HIV-1 NNRTIs
2019
·
Dongwei Kang
, Da Feng
, et al.
·
Acta Pharmaceutica Sinica B
·
59
PDF
Discovery of Novel Diarylpyrimidine Derivatives as Potent HIV-1 NNRTIs Targeting the “NNRTI Adjacent” Binding Site
2018
·
Zhipeng Huo
, Heng Zhang
, et al.
·
ACS Medicinal Chemistry Letters
·
42
Further Exploring Solvent-Exposed Tolerant Regions of Allosteric Binding Pocket for Novel HIV-1 NNRTIs Discovery
2018
·
Dongwei Kang
, Zhao Wang
, et al.
·
ACS Medicinal Chemistry Letters
·
33
Design, synthesis, and evaluation of novel heteroaryldihydropyrimidine derivatives as non‐nucleoside hepatitis B virus inhibitors by exploring the solvent‐exposed region
2019
·
Ji Yu
, Haiyong Jia
, et al.
·
Chemical Biology & Drug Design
·
23
Improved and ligand-free copper-catalyzed cyclization for an efficient synthesis of benzimidazoles from o -bromoarylamine and nitriles
2024
·
Emmanuel Mintah Bonku
, Hongjian Qin
, et al.
·
RSC Advances
·
11
PDF
Efficient Large-Scale Process for Tecovirimat via Reactive Distillation for the Preparation of Cycloheptatriene
2023
·
Emmanuel Mintah Bonku
, Hongjian Qin
, et al.
·
Organic Process Research & Development
·
11
Development of enhanced HIV-1 non-nucleoside reverse transcriptase inhibitors with improved resistance and pharmacokinetic profiles
2025
·
Zhao Wang
, Shawn Rumrill
, et al.
·
Science Advances
·
7
Impurity study of tecovirimat
2024
·
Emmanuel Mintah Bonku
, Hongjian Qin
, et al.
·
Heliyon
·
6
Discovery of peptidomimetic spiropyrrolidine derivatives as novel 3CLpro inhibitors against SARS-CoV -2
2024
·
Samuel Desta Guma
, Zhaoyin Zhou
, et al.
·
European Journal of Medicinal Chemistry
·
4
A review of the synthetic strategies toward the antiviral drug tecovirimat
2024
·
Emmanuel Mintah Bonku
, Hongjian Qin
, et al.
·
Organic & Biomolecular Chemistry
·
3
One-Pot Cyclocondensation Approach to Form 4-Amino-2-Pyridones via Ammonium Acetate as a Nitrogen Source
2025
·
Safomuddin Abduahadi
, Emmanuel Mintah Bonku
, et al.
·
The Journal of Organic Chemistry
·
2
An Efficient Asymmetric Synthesis of Finerenone via Evans’ Chiral Auxiliary
2025
·
Safomuddin Abduahadi
, Emmanuel Mintah Bonku
, et al.
·
European Journal of Organic Chemistry
·
2
Design, synthesis, and biological evaluation of thioamide-linked spiropyrrolidine derivatives as novel 3CLpro inhibitors against SARS-CoV-2
2025
·
Samuel Desta Guma
, Kang Song
, et al.
·
Bioorganic & Medicinal Chemistry
·
2
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Works count:
14
Citation count:
268
H-index:
7
I10-index:
7
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