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Xukun Deng

Observed names: Xu-Kun DENG, Xu-Kun Deng
ORCID: 0000-0001-6121-3374
Observed ORCIDs: 0000-0001-6121-3374, 0009-0009-3600-2669
OpenAlex ID: A5025876382
The anti-tumor effects of alkaloids from the seeds of Strychnos nux-vomica on HepG2 cells and its possible mechanism
2006 · Xu-Kun Deng, Wu Yin, et al. · Journal of Ethnopharmacology · 151
Polydatin ameliorates renal injury by attenuating oxidative stress-related inflammatory responses in fructose-induced urate nephropathic mice
2012 · Lvyi Chen, Zhou Lan, et al. · Food and Chemical Toxicology · 106
Astragalin Reduces Hexokinase 2 through Increasing miR-125b to Inhibit the Proliferation of Hepatocellular Carcinoma Cells in Vitro and in Vivo
2017 · Wei Li, Ji Hao, et al. · Journal of Agricultural and Food Chemistry · 84
The Apoptotic Effect of Brucine from the Seed of Strychnos nux-vomica on Human Hepatoma Cells is Mediated via Bcl-2 and Ca2+ Involved Mitochondrial Pathway
2006 · Xukun Deng, Fangzhou Yin, et al. · Toxicological Sciences · 77
Antitumor immunostimulatory activity of polysaccharides from Panax japonicus C. A. Mey: Roles of their effects on CD4 + T cells and tumor associated macrophages
2018 · Guangwen Shu, Shanqing Jiang, et al. · International Journal of Biological Macromolecules · 65
Brucine, an alkaloid from seeds of Strychnos nux-vomica Linn., represses hepatocellular carcinoma cell migration and metastasis: The role of hypoxia inducible factor 1 pathway
2013 · Guangwen Shu, Xue Mi, et al. · Toxicology Letters · 64
A novel electrochemiluminescence biosensor based on Ru(bpy)32+-functionalized MOF composites and cycle amplification technology of DNAzyme walker for ultrasensitive detection of kanamycin
2024 · Lu Zheng, Qing Li, et al. · Journal of Colloid and Interface Science · 58
Piperine inhibits AML-12 hepatocyte EMT and LX-2 HSC activation and alleviates mouse liver fibrosis provoked by CCl 4 : roles in the activation of the Nrf2 cascade and subsequent suppression of the TGF-β1/Smad axis
2021 · Guangwen Shu, Arslan Yusuf, et al. · Food & Function · 53
Dauricine upregulates the chemosensitivity of hepatocellular carcinoma cells: Role of repressing glycolysis via miR-199a:HK2/PKM2 modulation
2018 · Wei Li, Yunhan Qiu, et al. · Food and Chemical Toxicology · 51
Facile synthesis of novel poly(1H-benzoindole)/WO3 nanocomposites with enhanced energy storage capability and its application in high-performance supercapacitor
2022 · Huixue Zou, Xukun Deng, et al. · Journal of Electroanalytical Chemistry · 48
The cytotoxicity induced by brucine from the seed of Strychnos nux-vomica proceeds via apoptosis and is mediated by cyclooxygenase 2 and caspase 3 in SMMC 7221 cells
2007 · Wu Yin, Xu-Kun Deng, et al. · Food and Chemical Toxicology · 48
γ-Oryzanol alleviates acetaminophen-induced liver injury: roles of modulating AMPK/GSK3β/Nrf2 and NF-κB signaling pathways
2019 · Guangwen Shu, Yunhan Qiu, et al. · Food & Function · 47
High performance polythiophene derivative with good electrochromic and energy storage properties electrochemical synthesized in boron trifluoride diethyl etherate
2023 · Qingfu Guo, Chunhui Du, et al. · Dyes and Pigments · 43
A flavonoid component from Docynia delavayi (Franch.) Schneid represses transplanted H22 hepatoma growth and exhibits low toxic effect on tumor-bearing mice
2012 · Xiangpei Zhao, Guangwen Shu, et al. · Food and Chemical Toxicology · 37
Dandelion polyphenols protect against acetaminophen-induced hepatotoxicity in mice via activation of the Nrf-2/HO-1 pathway and inhibition of the JNK signaling pathway
2020 · Yong-Shen REN, Yao ZHENG, et al. · Chinese Journal of Natural Medicines · 36
Limonin relieves TGF-β-induced hepatocyte EMT and hepatic stellate cell activation in vitro and CCl4-induced liver fibrosis in mice via upregulating Smad7 and subsequent suppression of TGF-β/Smad cascade
2022 · Guangwen Shu, Chenxi Dai, et al. · The Journal of Nutritional Biochemistry · 34
Nuciferine alleviates acute alcohol-induced liver injury in mice: Roles of suppressing hepatic oxidative stress and inflammation via modulating miR-144/Nrf2/HO-1 cascade
2019 · Guangwen Shu, Yunhan Qiu, et al. · Journal of Functional Foods · 32
A characterized saponin extract of Panax japonicus suppresses hepatocyte EMT and HSC activation in vitro and CCl4-provoked liver fibrosis in mice: Roles of its modulatory effects on the Akt/GSK3β/Nrf2 cascade
2021 · Chenxi Dai, Arslan Yusuf, et al. · Phytomedicine · 31
Dolichos falcata Klein attenuated the inflammation induced by monosodium urate crystals in vivo and in vitro
2013 · Lvyi Chen, Mahmutjian Mola, et al. · Journal of Ethnopharmacology · 29
Anticoagulant active ingredients identification of total saponin extraction of different Panax medicinal plants based on grey relational analysis combined with UPLC-MS and molecular docking
2020 · Yongshen Ren, Jiao Ai, et al. · Journal of Ethnopharmacology · 28
Celecoxib alleviates AKT/c‐Met‐triggered rapid hepatocarcinogenesis by suppressing a novel COX‐2/AKT/FASN cascade
2018 · Zhenpeng Qiu, Cong Zhang, et al. · Molecular Carcinogenesis · 28
Anti-Tumor Effects of Flavonoids from the Ethnic Medicine Docynia delavayi (Franch.) Schneid. and Its Possible Mechanism
2014 · Xukun Deng, Xiangpei Zhao, et al. · Journal of Medicinal Food · 26
An electrochemiluminescence sensor for ultrasensitive detection of Hg2+ based on self-enhanced Ru-QDs@SiO2 luminophore and P6ICA/MoS2 as co-reaction accelerator
2023 · Dandan Liu, Jiuying Cui, et al. · Sensors and Actuators B Chemical · 25
Theaflavine inhibits hepatic stellate cell activation by modulating the PKA/LKB1/AMPK/GSK3β cascade and subsequently enhancing Nrf2 signaling
2023 · Guangwen Shu, Hui Sun, et al. · European Journal of Pharmacology · 22
Water extract of earthworms mitigates kidney injury triggered by oxidative stress via activating intrarenal Sirt1/Nrf2 cascade and ameliorating mitochondrial damage
2024 · Guangwen Shu, Chuo Wang, et al. · Journal of Ethnopharmacology · 21
Works count: 51
Citation count: 1,399
H-index: 24
I10-index: 32
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