Author

Truc Do

Institution: Merck & Co., Inc., Rahway, NJ, USA (United States)

Observed institutions: Merck & Co., Inc., Rahway, NJ, USA (United States), Harvard University, Princeton University

ORCID: 0000-0001-7212-0296

Observed ORCID: 0000-0001-7212-0296

OpenAlex ID: A5025930575

Uncovering the activities, biological roles, and regulation of bacterial cell wall hydrolases and tailoring enzymes

2020 · Truc Do, Julia E. Page, et al. · Journal of Biological Chemistry · 110

Mechanisms of action of ribosomally synthesized and posttranslationally modified peptides (RiPPs)

2021 · Li Cao, Truc Do, et al. · Journal of Industrial Microbiology & Biotechnology · 93

Genome-wide mutant profiling predicts the mechanism of a Lipid II binding antibiotic

2018 · Marina Santiago, Wonsik Lee, et al. · Nature Chemical Biology · 70

Staphylococcus aureus cell growth and division are regulated by an amidase that trims peptides from uncrosslinked peptidoglycan

2020 · Truc Do, Kaitlin Schaefer, et al. · Nature Microbiology · 63

The Length of Lipoteichoic Acid Polymers Controls Staphylococcus aureus Cell Size and Envelope Integrity

2020 · Anthony R. Hesser, Leigh M. Matano, et al. · Journal of Bacteriology · 60

Protein Engineering in Ribosomally Synthesized and Post-translationally Modified Peptides (RiPPs)

2022 · Truc Do, A. James Link · Biochemistry · 35

High-Throughput Screen Reveals the Structure–Activity Relationship of the Antimicrobial Lasso Peptide Ubonodin

2023 · Alina Thokkadam, Truc Do, et al. · ACS Central Science · 31

Phenotype-Guided Comparative Genomics Identifies the Complete Transport Pathway of the Antimicrobial Lasso Peptide Ubonodin in Burkholderia

2022 · Truc Do, Alina Thokkadam, et al. · ACS Chemical Biology · 20

Biocatalytic cascades enable manufacture of the macrocyclic peptide enlicitide

2026 · Artis Klapars, Anna Fryszkowska, et al. · Science · 17

Genome Mining and Discovery of Imiditides, a Family of RiPPs with a Class-Defining Aspartimide Modification

2023 · Li Cao, Truc Do, et al. · Journal of the American Chemical Society · 14

Antibiotic Combinations That Enable One-Step, Targeted Mutagenesis of Chromosomal Genes

2018 · Wonsik Lee, Truc Do, et al. · ACS Infectious Diseases · 13

Metal cofactor stabilization by a partner protein is a widespread strategy employed for amidase activation

2022 · Julia E. Page, Meredith A. Skiba, et al. · Proceedings of the National Academy of Sciences · 12

Antimicrobial Lasso Peptide Cloacaenodin Utilizes a Unique TonB-Dependent Transporter to Access Susceptible Bacteria

2024 · Drew V. Carson, Reecan J. Juarez, et al. · ACS Chemical Biology · 8

Cysimiditides: RiPPs with a Zn-Tetracysteine Motif and Aspartimidylation

2025 · Angela Zhu, Li Cao, et al. · Biochemistry · 4

The Anti- Burkholderia Lasso Peptide Ubonodin Co-Opts the Siderophore Receptor PupB for Cellular Entry

2022 · Truc Do, Alina Thokkadam, et al. · bioRxiv (Cold Spring Harbor Laboratory)

Works count: 15

Citation count: 550

H-index: 12

I10-index: 12