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Sevim Işık

Observed names: Isik, Sevim, S. Isık, Sevim Isik, Sevim Isık
ORCID: 0000-0001-7687-6082
Observed ORCID: 0000-0001-7687-6082
OpenAlex ID: A5026052157
Microglia Mediated Neuroinflammation in Parkinson’s Disease
2023 · Sevim Isik, Bercem Yeman Kiyak, et al. · Cells · 412
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Donor age and long-term culture affect differentiation and proliferation of human bone marrow mesenchymal stem cells
2012 · Merve Zaim, Serap Karaman, et al. · Annals of Hematology · 303
Preparation and characterization of amine functional nano-hydroxyapatite/chitosan bionanocomposite for bone tissue engineering applications
2017 · Besir Hakan Atak, Berna Buyuk, et al. · Carbohydrate Polymers · 123
Preparation and in vitro evaluation of 5-flourouracil loaded magnetite–zeolite nanocomposite (5-FU-MZNC) for cancer drug delivery applications
2015 · Tuğba Sağir, Merve Huysal, et al. · Biomedicine & Pharmacotherapy · 71
Highly sensitive detection of cancer cells with an electrochemical cytosensor based on boronic acid functional polythiophene
2016 · Muamer Dervisevic, Mehmet Senel, et al. · Biosensors and Bioelectronics · 64
Delivery of lipophilic porphyrin by liposome vehicles: Preparation and photodynamic therapy activity against cancer cell lines
2014 · Emine Temizel, Tugba Sagir, et al. · Photodiagnosis and Photodynamic Therapy · 55
Folic acid conjugated PAMAM-modified mesoporous silica-coated superparamagnetic iron oxide nanoparticles for potential cancer therapy
2022 · T. Sagir, M. Huysal, et al. · Journal of Colloid and Interface Science · 52
The SUMO pathway is required for selective degradation of DNA topoisomerase IIβ induced by a catalytic inhibitor ICRF‐1931
2003 · Sevim Isik, Kuniaki Sano, et al. · FEBS Letters · 47
Preparation and characterization of novel chitosan/zeolite scaffolds for bone tissue engineering applications
2017 · Rovshen Akmammedov, Merve Huysal, et al. · International Journal of Polymeric Materials · 36
Advances in Neurodegenerative Disease Therapy: Stem Cell Clinical Trials and Promise of Engineered Exosomes
2025 · Sevim Isik, Sajeda Osman, et al. · CNS Neuroscience & Therapeutics · 34
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Plant-derived exosome-like nanovesicles: mechanisms and molecular understanding in neurological disorders with potential therapeutic applications
2025 · Sevim Isik, Sedra Alhelwani, et al. · Drug Delivery and Translational Research · 32
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Cellular Model of Alzheimer's Disease: Aβ1-42 Peptide Induces Amyloid Deposition and a Decrease in Topo Isomerase IIβ and Nurr1 Expression
2017 · Sule Terzioglu-Usak, Yesim Negis, et al. · Current Alzheimer Research · 31
Boronic Acid vs. Folic Acid: A Comparison of the bio-recognition performances by Impedimetric Cytosensors based on Ferrocene cored dendrimer
2017 · Muamer Dervisevic, Mehmet Şenel, et al. · Biosensors and Bioelectronics · 27
DNA topoisomerase IIβ as a molecular switch in neural differentiation of mesenchymal stem cells
2014 · Sevim Isik, Merve Zaim, et al. · Annals of Hematology · 25
Proliferative and apoptotic effects of olive extracts on cell lines and healthy human cells
2012 · Sevim Işık, Aysel Karagöz, et al. · Food Chemistry · 22
DNA topoisomerase IIβ stimulates neurite outgrowth in neural differentiated human mesenchymal stem cells through regulation of Rho-GTPases (RhoA/Rock2 pathway) and Nurr1 expression
2018 · Merve Zaim, Sevim Isik · Stem Cell Research & Therapy · 19
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Comparison of long-term retinoic acid-based neural induction methods of bone marrow human mesenchymal stem cells
2011 · Busra Mammadov, Nihal Karakas, et al. · In Vitro Cellular & Developmental Biology - Animal · 16
Proposing novel natural compounds against Alzheimer’s disease targeting acetylcholinesterase
2023 · Münteha Girgin, Sevim Isik, et al. · PLoS ONE · 15
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Selective silencing of DNA topoisomerase IIβ in human mesenchymal stem cells by siRNAs (small interfering RNAs)
2011 · Nebiyyeh Kamaci, Tuba Emnacar, et al. · Cell Biology International Reports · 14
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Neuroprotective effects of Cubebin and Hinokinin lignan fractions of Piper cubeba fruit in Alzheimer’s disease in vitro model
2023 · Shirin Tarbiat, Demet Unver, et al. · Turkish Journal of Biochemistry · 13
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Influence of gold nanoparticle architecture on in vitro bioimaging and cellular uptake
2014 · Ozlem Polat, Aysel Karagoz, et al. · Journal of Nanoparticle Research · 11
Ferrocene incorporated PAMAM dendrons: synthesis, characterization, and anti-cancer activity against AGS cell line
2013 · Tuğba Sağır, Sevim Işık, et al. · Medicinal Chemistry Research · 11
Down regulation of DNA topoisomerase IIβ exerts neurodegeneration like effect through Rho GTPases in cellular model of Parkinson’s disease by Down regulating tyrosine hydroxylase
2021 · Kiyak Bercem Yeman, Sevim Isik · Neurological Research · 9
Knockdown of c-MYC Controls the Proliferation of Oral Squamous Cell Carcinoma Cells in vitro via Dynamic Regulation of Key Apoptotic Marker Genes.
2021 · Hussein Sabit, Huseyin Tombuloglu, et al. · PubMed Central · 8
Exploring the Neuroprotective Properties of Celery (Apium graveolens Linn) Extract Against Amyloid-Beta Toxicity and Enzymes Associated with Alzheimer’s Disease
2025 · Layla Mohamud Dirie, Tahire Yurdakul, et al. · Molecules · 7
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Works count: 50
Citation count: 1,496
H-index: 16
I10-index: 22
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