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Sven Mathias
Observed names:
Mathias, Sven,
S Mathias
Institution:
Sartorius (Germany)
Observed institutions:
Boehringer Ingelheim (Germany),
Radboud University Nijmegen,
Universität Ulm,
University of Applied Sciences Biberach,
Sartorius (Germany),
Donders Institute for Brain, Cognition and Behaviour,
University of Duisburg-Essen
show all 7
ORCID:
0000-0002-2842-8549
Observed ORCID:
0000-0002-2842-8549
OpenAlex ID:
A5026386052
A functional high‐content miRNA screen identifies miR‐30 family to boost recombinant protein production in CHO cells
2014
·
Simon Fischer
, Theresa Buck
, et al.
·
Biotechnology Journal
·
68
Unraveling what makes a monoclonal antibody difficult‐to‐express: From intracellular accumulation to incomplete folding and degradation via ERAD
2019
·
Sven Mathias
, Anna Wippermann
, et al.
·
Biotechnology and Bioengineering
·
52
PDF
CRISPR/Cas9‐Mediated Knockout of MicroRNA‐744 Improves Antibody Titer of CHO Production Cell Lines
2019
·
Nadja Raab
, Sven Mathias
, et al.
·
Biotechnology Journal
·
47
miR‐2861 as novel HDAC5 inhibitor in CHO cells enhances productivity while maintaining product quality
2015
·
Simon Fischer
, Albert Jesuran Paul
, et al.
·
Biotechnology and Bioengineering
·
45
Enhanced protein production by microRNA-30 family in CHO cells is mediated by the modulation of the ubiquitin pathway
2015
·
Simon Fischer
, Sven Mathias
, et al.
·
Journal of Biotechnology
·
36
Visualisation of intracellular production bottlenecks in suspension-adapted CHO cells producing complex biopharmaceuticals using fluorescence microscopy
2018
·
Sven Mathias
, Simon Fischer
, et al.
·
Journal of Biotechnology
·
32
Human CAP cells represent a novel source for functional, miRNA-loaded exosome production
2019
·
Nikolas Zeh
, Helga Schneider
, et al.
·
PLoS ONE
·
24
PDF
Rational optimization of a monoclonal antibody improves the aggregation propensity and enhances the CMC properties along the entire pharmaceutical process chain
2020
·
Joschka Bauer
, Sven Mathias
, et al.
·
mAbs
·
22
PDF
A blueprint from nature: miRNome comparison of plasma cells and CHO cells to optimize therapeutic antibody production
2021
·
Nadja Raab
, Nikolas Zeh
, et al.
·
New Biotechnology
·
18
PDF
Unveiling the CHO surfaceome: Identification of cell surface proteins reveals cell aggregation‐relevant mechanisms
2021
·
Florian Klingler
, Sven Mathias
, et al.
·
Biotechnology and Bioengineering
·
13
PDF
Loss of a newly discovered microRNA in Chinese hamster ovary cells leads to upregulation of N‐glycolylneuraminic acid sialylation on monoclonal antibodies
2021
·
Simon Fischer
, Sven Mathias
, et al.
·
Biotechnology and Bioengineering
·
10
Advancing Raman Calibration: Automated Data Generation, Monitoring, and Control in Multi‐Parallel Perfusion Mini Bioreactors
2026
·
Rafael Machleid
, Maximilian Goertz
, et al.
·
Biotechnology Journal
·
1
Antibody reproducibility challenges: the solution lies in the sequence
2016
·
Andrew Bradbury
, Glenn Begley
, et al.
·
Nature
·
1
Identification, characterization and removal of intracellular secretion bottlenecks in industrial CHO production cell lines
2020
·
Mathias, Sven
·
OPen Access Repositorium der Universität Ulm (OPARU) (Ulm University)
CRISPR/Cas9 mediated knockout of microRNAs for precise cell engineering
2018
·
Nadja Raab
, Kerstin Alt
, et al.
The N-terminus of human monocarboxylate transporter 8 is a target of ubiquitin depending proteasomal degradation
2015
·
D Zwanziger
, J Fischer
, et al.
·
Experimental and Clinical Endocrinology & Diabetes
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Works count:
16
Citation count:
369
H-index:
10
I10-index:
11
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