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Alexander Greenhough

Observed names: A Greenhough, A. Greenhough, Alex Greenhough, Alexander Greenhough (6590423), Greenhough A., Greenhough, Alexander
Observed institutions: University of Sussex, University of the West of England, University of Cambridge, Cancer Research UK, The Gurdon Institute, University of Bristol
ORCID: 0000-0002-8306-811X
Observed ORCID: 0000-0002-8306-811X
OpenAlex ID: A5026435394
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
2016 · Daniel J Klionsky, Kotb Abdelmohsen, et al. · Autophagy · 5,890
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1
2021 · Daniel J. Klionsky, Amal Kamal Abdel-Aziz, et al. · Autophagy · 2,608
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The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment
2009 · A. Greenhough, H. J.M. Smartt, et al. · Carcinogenesis · 1,217
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Autolysosomal β‐catenin degradation regulates Wnt‐autophagy‐p62 crosstalk
2013 · Katy J Petherick, Ann C Williams, et al. · The EMBO Journal · 319
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Live imaging of wound angiogenesis reveals macrophage orchestrated vessel sprouting and regression
2018 · David B Gurevich, Charlotte E Severn, et al. · The EMBO Journal · 275
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The cannabinoid δ9‐tetrahydrocannabinol inhibits RAS‐MAPK and PI3K‐AKT survival signalling and induces BAD‐mediated apoptosis in colorectal cancer cells
2007 · Alexander Greenhough, Helena A. Patsos, et al. · International Journal of Cancer · 155
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
2021 · Klionsky, Daniel J, Abdel-Aziz, Amal Kamal, et al. · Research at the University of Copenhagen (University of Copenhagen) · 104
Cancer cell adaptation to hypoxia involves a HIF‐GPRC5A‐YAP axis
2018 · Alexander Greenhough, Clare Bagley, et al. · EMBO Molecular Medicine · 87
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Long-range epigenetic silencing of chromosome 5q31 protocadherins is involved in early and late stages of colorectal tumorigenesis through modulation of oncogenic pathways
2012 · A R Dallosso, B Øster, et al. · Oncogene · 87
LGR5 regulates pro-survival MEK/ERK and proliferative Wnt/β-catenin signalling in neuroblastoma
2015 · Gabriella Cunha Vieira, S. Chockalingam, et al. · Oncotarget · 75
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LGR5 promotes survival in human colorectal adenoma cells and is upregulated by PGE 2 : implications for targeting adenoma stem cells with NSAIDs
2013 · Manal R.A. Al-Kharusi, Helena J.M. Smartt, et al. · Carcinogenesis · 69
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Erratum
2016 · Klionsky D. J., Abdelmohsen K., et al. · Autophagy · 65
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LEF-1 drives aberrant β-catenin nuclear localization in myeloid leukemia cells
2019 · Rhys G. Morgan, Jenna Ridsdale, et al. · Haematologica · 56
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BCL-3 expression promotes colorectal tumorigenesis through activation of AKT signalling
2015 · Bettina C Urban, Tracey J Collard, et al. · Gut · 53
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Protein arginine methyltransferase 5 is a key regulator of the MYCN oncoprotein in neuroblastoma cells
2014 · Ji Hyun Park, Marianna Szemes, et al. · Molecular Oncology · 53
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HGF/Met signalling promotes PGE2 biogenesis via regulation of COX-2 and 15-PGDH expression in colorectal cancer cells
2009 · A. E. Moore, A. Greenhough, et al. · Carcinogenesis · 53
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β-catenin represses expression of the tumour suppressor 15-prostaglandin dehydrogenase in the normal intestinal epithelium and colorectal tumour cells
2011 · Helena J M Smartt, Alexander Greenhough, et al. · Gut · 51
Colon tumour cells increase PGE2 by regulating COX-2 and 15-PGDH to promote survival during the microenvironmental stress of glucose deprivation
2011 · H. R. Roberts, H. J. M. Smartt, et al. · Carcinogenesis · 48
Optimized delivery of siRNA into 3D tumor spheroid cultures in situ
2018 · R. G. Morgan, A. C. Chambers, et al. · Scientific Reports · 46
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Hypomethylation and Aberrant Expression of the Glioma Pathogenesis-Related 1 Gene in Wilms Tumors
2007 · Laxmi Chilukamarri, Anne L. Hancock, et al. · Neoplasia · 45
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The proapoptotic BH3-only protein Bim is downregulated in a subset of colorectal cancers and is repressed by antiapoptotic COX-2/PGE2 signalling in colorectal adenoma cells
2010 · A Greenhough, C A Wallam, et al. · Oncogene · 43
Wnt Signalling Drives Context-Dependent Differentiation or Proliferation in Neuroblastoma
2018 · Marianna Szemes, Alexander Greenhough, et al. · Neoplasia · 37
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Cannabinoids and cancer: potential for colorectal cancer therapy
2005 · H.A. Patsos, D.J. Hicks, et al. · Biochemical Society Transactions · 36
BCL-3 promotes a cancer stem cell phenotype by enhancing β-catenin signalling in colorectal tumour cells
2019 · Danny N. Legge, Alex P. Shephard, et al. · Disease Models & Mechanisms · 33
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Wnt Signaling Is a Major Determinant of Neuroblastoma Cell Lineages
2019 · Marianna Szemes, Alexander Greenhough, et al. · Frontiers in Molecular Neuroscience · 27
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Works count: 54
Citation count: 11,720
H-index: 25
I10-index: 33
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