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Takehisa Kawata

Observed names: Kawata, Takehisa, T Kawata, T. Kawata
Institution: Kyowa Kirin (Japan)
ORCID: 0000-0002-1167-6925
Observed ORCID: 0000-0002-1167-6925
OpenAlex ID: A5027470042
Therapeutic Effects of Anti-FGF23 Antibodies in Hypophosphatemic Rickets/Osteomalacia
2009 · Yukiko Aono, Yuji Yamazaki, et al. · Journal of Bone and Mineral Research · 273
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Parathyroid Hormone Regulates Fibroblast Growth Factor-23 in a Mouse Model of Primary Hyperparathyroidism
2007 · Takehisa Kawata, Yasuo Imanishi, et al. · Journal of the American Society of Nephrology · 211
Cinacalcet suppresses calcification of the aorta and heart in uremic rats
2008 · Takehisa Kawata, Nobuo Nagano, et al. · Kidney International · 116
Regulation of plasma fibroblast growth factor 23 by calcium in primary hyperparathyroidism
2005 · Keisuke Kobayashi, Yasuo Imanishi, et al. · European Journal of Endocrinology · 103
Expression of FGF23 is correlated with serum phosphate level in isolated fibrous dysplasia
2005 · Keisuke Kobayashi, Yasuo Imanishi, et al. · Life Sciences · 85
Design and synthesis of Rho kinase inhibitors (II)
2006 · Masayuki Iwakubo, Atsuya Takami, et al. · Bioorganic & Medicinal Chemistry · 84
Design and synthesis of Rho kinase inhibitors (I)
2004 · Atsuya Takami, Masayuki Iwakubo, et al. · Bioorganic & Medicinal Chemistry · 74
A novel calcimimetic agent, evocalcet (MT-4580/KHK7580), suppresses the parathyroid cell function with little effect on the gastrointestinal tract or CYP isozymes in vivo and in vitro
2018 · Takehisa Kawata, Shin Tokunaga, et al. · PLoS ONE · 72
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Direct in vitro evidence of the suppressive effect of cinacalcet HCl on parathyroid hormone secretion in human parathyroid cells with pathologically reduced calcium-sensing receptor levels
2006 · Takehisa Kawata, Yasuo Imanishi, et al. · Journal of Bone and Mineral Metabolism · 46
Discovery of evocalcet, a next-generation calcium-sensing receptor agonist for the treatment of hyperparathyroidism
2018 · Hiroshi Miyazaki, Yousuke Ikeda, et al. · Bioorganic & Medicinal Chemistry Letters · 41
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Design and synthesis of rho kinase inhibitors (III)
2006 · Masayuki Iwakubo, Atsuya Takami, et al. · Bioorganic & Medicinal Chemistry · 41
Relationship between parathyroid calcium-sensing receptor expression and potency of the calcimimetic, cinacalcet, in suppressing parathyroid hormone secretion in an in vivo murine model of primary hyperparathyroidism
2005 · Takehisa Kawata, Yasuo Imanishi, et al. · European Journal of Endocrinology · 41
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Evocalcet Rescues Secondary Hyperparathyroidism-driven Cortical Porosity in CKD Male Rats
2023 · Tomoka Hasegawa, Shin Tokunaga, et al. · Endocrinology · 31
Cinacalcet HCl Suppresses Cyclin D1 Oncogene-Derived Parathyroid Cell Proliferation in a Murine Model for Primary Hyperparathyroidism
2011 · Yasuo Imanishi, Takehisa Kawata, et al. · Calcified Tissue International · 23
Directin VitroEvidence of Extracellular Ca2+-Induced Amino-Terminal Truncation of Human Parathyroid Hormone (1–84) by Human Parathyroid Cells
2005 · Takehisa Kawata, Yasuo Imanishi, et al. · The Journal of Clinical Endocrinology & Metabolism · 22
Evocalcet prevents ectopic calcification and parathyroid hyperplasia in rats with secondary hyperparathyroidism
2020 · Mariko Sakai, Shin Tokunaga, et al. · PLoS ONE · 21
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Micronucleus test with cyclophosphamide using mouse peripheral blood reticulocytes
1992 · Y Hatanaka, Y Kitagawa, et al. · Mutation Research/Genetic Toxicology · 19
Animal models of hyperfunctioning parathyroid diseases for drug development
2009 · Yasuo Imanishi, Masaaki Inaba, et al. · Expert Opinion on Drug Discovery · 17
Regulatory Mechanisms of Circulating Fibroblast Growth Factor 23 in Parathyroid Diseases
2007 · Yasuo Imanishi, Keisuke Kobayashi, et al. · Therapeutic Apheresis and Dialysis · 12
Development of evocalcet for unmet needs among calcimimetic agents
2020 · Naoto Hamano, Yuichi Endo, et al. · Expert Review of Endocrinology & Metabolism · 9
Evocalcet with vitamin D receptor activator treatment for secondary hyperparathyroidism
2022 · Takashi Shigematsu, Shinji Asada, et al. · PLoS ONE · 8
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Pharmacological and clinical profiles of a novel calcimimetic, evocalcet (ORKEDIA®)
2019 · Shin Tokunaga, Yuichi Endo, et al. · Folia Pharmacologica Japonica · 8
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Cinacalcet in Hyperfunctioning Parathyroid Diseases
2009 · Yasuo Imanishi, Masaaki Inaba, et al. · Therapeutic Apheresis and Dialysis · 8
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The effect of evocalcet on vagus nerve activity of the gastrointestinal tract in miniature pigs
2021 · Shin Tokunaga, Takehisa Kawata · PLoS ONE · 6
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[The calcium receptor and magnesium metabolism].
2005 · Takehisa Kawata, Nobuo Nagano · PubMed · 5
Works count: 40
Citation count: 1,396
H-index: 17
I10-index: 19
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